Clinical trials
Hysterectomy clinical trials
Below are recruiting hysterectomy clinical trials, each written for real people, not researchers. We’re tracking 73 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06658145Recruiting
New tool for vaginal hysterectomy for fibroids
This trial tests a new tool that helps doctors see better during vaginal hysterectomy (removing the uterus through the vagina). It is for women with uterine fibroids who need this surgery, and aims to see if it is safe and works well.
Beijing, Beijing MunicipalityAges Up to 60 years - NCT07379411Recruiting
Energy devices vs. cold scalpel for tube and ovary removal during vaginal hysterectomy
This trial is comparing two ways to remove the fallopian tubes and ovaries during a vaginal hysterectomy for pelvic organ prolapse: one using energy-based devices (like a cauterizing tool) and the other using a standard cold scalpel method. It will help determine if the energy-based approach offers any benefits, such as less blood loss or faster recovery.
HolonAges 18 years+ - NCT07335432Enrolling by invitation
Vitamin C to reduce blood loss during hysterectomy
This trial tests whether giving vitamin C through a vein before surgery can reduce blood loss during a total abdominal hysterectomy. If you are having this surgery and do not have bleeding problems or other exclusions, this study may help determine a way to make the procedure safer.
Si Racha, Changwat Chon BuriAges 20 years+ - NCT07324967Recruiting
Counseling for transmasculine patients before gender-affirming surgery
This study tests a counseling approach to help transmasculine and non-binary people prepare for a hysterectomy (removal of the uterus) as part of gender-affirming care. The goal is to see if this counseling improves knowledge and decision-making.
Minneapolis, MinnesotaAges 18–65 - NCT07313839Recruiting
Comparing two suture types for vaginal vault closure after hysterectomy
This trial tests if a self-locking suture works better than a traditional one when closing the vaginal vault during laparoscopic or robotic hysterectomy for gynecologic cancer. It aims to find a safer and more effective method for this part of the surgery.
Parma, ItalyAges 18 years+ - NCT06502548Recruiting
Endometriosis gene mapping study
This study collects tissue samples during surgery to create a detailed map of genes in endometriosis. It may help researchers understand why some people have more severe symptoms.
ToulouseAges 18–45 - NCT07195305Recruiting
Treating adenomyosis bleeding with heat or artery blocking
This study compares two treatments for heavy bleeding caused by adenomyosis: a procedure that uses heat to remove the inner lining of the uterus (endometrial ablation) and a procedure that blocks blood flow to the uterus (uterine artery embolization). If you have been diagnosed with adenomyosis and have tried medication without success, this trial may help decide which treatment is best for you.
BordeauxAges 30–50 - NCT07174921Recruiting
Vaginal cuff prolapse repair after hysterectomy
This trial tests a surgery to fix vaginal cuff prolapse (when the top of the vagina drops down) in women who have had a hysterectomy. It may help relieve symptoms and improve quality of life.
Istanbul, IstanbulAges 18 years+ - NCT07130240RecruitingPhase 2
Ivonescimab with chemo before surgery for cervical cancer
This trial tests adding a new drug called Ivonescimab to standard chemotherapy (paclitaxel and cisplatin) given before a hysterectomy in women with cervical cancer stage IB2 or IIA1 (tumor size 2-4 cm). The goal is to see if this combination improves outcomes compared to chemo alone.
ShanghaiAges 18–75 - NCT07101250RecruitingPhase 4
Study of acetazolamide before laparoscopic hysterectomy
This trial tests a medication called acetazolamide given before surgery to see if it can help prevent shoulder pain after a laparoscopic hysterectomy. If you are a woman scheduled for this type of hysterectomy, you may be able to join.
Greenville, South CarolinaAges 21–65 - NCT07075731Recruiting
Cervical and endometrial cancer screening before gender-affirming hysterectomy
This study looks at how to best screen for cervical and endometrial (uterine lining) cancer in transgender and gender-diverse people who have had or plan to have a hysterectomy (surgery to remove the uterus and cervix). It aims to make screening more comfortable and effective for this community.
Minneota, MinnesotaAges 18 years+ - NCT07067645Recruiting
Vaginal length after hysterectomy: comparing two closure methods
This trial compares two ways of closing the vagina after a hysterectomy for severe uterine prolapse to see which method keeps more vaginal length. It may help women who want to preserve vaginal depth after surgery.
IstanbulAges 35–65 - NCT06766994Recruiting
Pain relief methods after hysterectomy: a recovery comparison
This study compares two different ways to manage pain after abdominal hysterectomy surgery. The goal is to see which method helps you recover better and feel more comfortable.
Erzurum, YakutiyeAges 18–65 - NCT06996561RecruitingPhase 2/Phase 3
How your genes affect pain relief after surgery
This study looks at how your genes might affect pain relief from a medication called nalbuphine after abdominal or pelvic surgery. It aims to personalize pain management based on your genetic makeup.
Karachi, SindhAges 18–70 - NCT06806280Recruiting
Breathing after robotic hysterectomy for endometrial cancer
This study looks at how your breathing changes after a robotic-assisted hysterectomy for endometrial cancer. It aims to help doctors understand recovery and improve care.
GothenburgAges 18 years+ - NCT06671639Recruiting
Stanford program to speed up robotic surgery for children
This trial tests a faster, robotic-assisted surgery for children ages 6 to 21. It aims to see if completing part of the operation using a robot can be as safe and effective as traditional open surgery, possibly leading to quicker recovery and less pain.
Stanford, CaliforniaAges 6–21 - NCT06536517RecruitingPhase 2
Methadone during hysterectomy to reduce pain pills
This study tests whether a single dose of methadone given during minimally invasive hysterectomy (for non-cancer reasons) can reduce the need for opioid pain pills after surgery. It aims to see if this approach helps with pain control and lessens opioid use.
Baltimore, MarylandAges 18 years+ - NCT06483659RecruitingPhase 2
Oxytocin for pain after minimally invasive hysterectomy
This study tests if giving oxytocin (a natural hormone) through an IV can help reduce pain after a minimally invasive hysterectomy. If you are having this surgery, you may be able to join.
Boston, MassachusettsAges 18–65 - NCT06445179Recruiting
Robotic surgery for adenomyosis and endometriosis
This trial tests robotic-assisted surgery to remove the uterus (hysterectomy) and all endometriosis lesions in people with both adenomyosis and deep endometriosis. It's for those who haven't found relief from medical treatments and are ready for surgery.
Aix-en-ProvenceAges 18 years+ - NCT06191133RecruitingPhase 1
Fenofibrate for cervical pre-cancer and cancer
This study tests whether a cholesterol-lowering drug called fenofibrate can help people with cervical pre-cancer or cancer. You take the drug before your scheduled surgery or chemoradiation, and doctors check if it reduces abnormal tissue or enhances treatment.
Cleveland, OhioAges 18 years+ - NCT05953766RecruitingPhase 2
Nerve block versus sham block after hysterectomy
This trial compares a targeted pain-relief injection near the lower back (a “nerve block”) to a sham (placebo-like) procedure during recovery from a total laparoscopic hysterectomy. It aims to see whether the real block reduces post-operative pain.
Toronto, OntarioAges 18 years+ - NCT05969457RecruitingPhase 3
Local pain-numbing injection before surgery for hysterectomy
This Phase 3 study tests whether a preventive numbing medicine injection before a vaginal hysterectomy (using the vNOTES approach) can reduce pain afterward. It may help with comfort and recovery after surgery for non-cancer reasons.
Le HavreAges 18–70 - NCT05337566Recruiting
Extra antibiotic before hysterectomy to prevent infections
This trial tests whether giving extra antibiotic (azithromycin) before hysterectomy can lower the chance of infections after surgery. You might benefit by helping prevent post-surgery infection, but it also depends on your allergy history and heart rhythm risks.
HelsinkiAges 18 years+ - NCT04831580Recruiting
Robotic vs open hysterectomy for early cervix cancer
This trial compares robotic surgery to open (traditional) surgery for women with early-stage cervix cancer. The goal is to see which approach is safer and works better for cancer control and recovery.
Goodyear, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for hysterectomy?
- Yes. Clin2 currently lists 73 recruiting hysterectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a hysterectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a hysterectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.