Clinical trials
Infections clinical trials
Below are recruiting infections clinical trials, each written for real people, not researchers. We’re tracking 1,666 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05590455RecruitingPhase 2
Testing a TNF-blocking drug to reduce death in HIV and TB meningitis
This Phase 2 trial studies whether a TNF-blocking medicine can lower the risk of death in people with HIV who also have TB meningitis. You would receive standard TB meningitis treatment plus the study drug, if you meet the criteria.
Rio de JaneiroAges 18 years+ - NCT05586776RecruitingPhase 4
Using skin cleaning to prevent post-surgery wound infections
This trial tests a “skin decolonization” routine using medicated skin cleaning to help lower the risk of surgical site infections after abdominal surgery. You may be eligible if you recently had an open abdominal incision and your wound is healing as expected at discharge.
Newport Beach, CaliforniaAges 18 years+ - NCT05474430Recruiting
Study testing how common lung infections relate to CF gene status
This study looks at whether carrying one CF gene (being a “CF carrier”) changes the risk of getting respiratory infections. It may help researchers understand how genetics can affect lung health, even for people who do not have cystic fibrosis.
Iowa City, IowaAges 18–100 - NCT05471973Recruiting
Study for suspected heart device infection care improvement
This study is testing an approach to improve how clinicians care for people with suspected infections around an implanted heart device (like a pacemaker or defibrillator). It may help ensure the infection is recognized and treated appropriately, especially when device removal (extraction) might be needed.
Chicago, IllinoisAges 18 years+ - NCT05458700Recruiting
Study of complicated urinary tract infections
This study looks at complicated urinary tract infections (UTIs), which are infections in the urinary system that happen when there is an underlying issue like a urinary catheter, blockage, or other urinary tract problem. The trial aims to gather information to better understand and treat these infections.
Seville, SevillaAges 18 years+ - NCT05446571RecruitingPhase 3
Letermovir in pregnancy versus valaciclovir for fetal CMV
This trial tests whether letermovir can treat a baby’s early (first-trimester) congenital CMV infection in pregnancy, compared with the standard drug valaciclovir. The goal is to reduce serious effects from CMV while monitoring safety and pregnancy outcomes.
ParisAges 18 years+ - NCT05369052RecruitingPhase 3
New antibiotic for moderate or severe diabetic foot infections
This Phase 3 trial tests a new medicine (contezolid acefosamil, and contezolid) to treat moderate or severe diabetic foot infections. It compares the new treatment to linezolid to see which works better and is safer for adults.
Corona, CaliforniaAges 18 years+ - NCT05398679RecruitingPhase 4
Oral antibiotics versus IV antibiotics after heart infection
This trial compares taking antibiotics by mouth versus receiving antibiotics through a vein (outpatient IV) for an infection of the heart valve. It’s designed to see whether the oral option can work as well and safely, especially after initial treatment and surgery if needed.
Alicante, AlicanteAges 18 years+ - NCT05361941Recruiting
Antibiotic graft to help bone regrow in infected knee surgery areas
This trial tests an antibiotic “graft” placed into or near infected bone cavities around a knee replacement (TKA) to help new bone grow. You may be considered if you have an infected knee implant area and can safely take part in follow-up visits and treatment.
Los Angeles, CaliforniaAges 22 years+ - NCT05337566Recruiting
Extra antibiotic before hysterectomy to prevent infections
This trial tests whether giving extra antibiotic (azithromycin) before hysterectomy can lower the chance of infections after surgery. You might benefit by helping prevent post-surgery infection, but it also depends on your allergy history and heart rhythm risks.
HelsinkiAges 18 years+ - NCT05334706RecruitingPhase 4
Vaccine study to lower HPV spread in HPV-positive women
This Phase 4 study tests whether a 9-type HPV vaccine (9vHPV) can reduce how infectious HPV is and lower the chance of HPV spreading in women who already have HPV16 and/or HPV18. It focuses on specific HPV-positive women recently diagnosed and compares what happens after vaccination.
L'Hospitalet de Llobregat, CataloniaAges 18 years+ - NCT05325008RecruitingPhase 3
IVIG treatment for BK virus after kidney transplant
This Phase 3 trial tests IVIG (an antibody medicine given through a vein) to treat BK virus infection after kidney or pancreas-kidney transplant. It may help lower the BK virus in the blood and protect the transplanted kidney.
Canberra, Australian Capital TerritoryAges 2 years+ - NCT05332444RecruitingPhase 4
Check if stomach-bacteria testing improves rescue treatment for H. pylori
This study compares two ways to treat Helicobacter pylori (H. pylori) infection that didn’t go away with prior therapy. One approach uses test results to guide which medicines to use, and the other uses standard (“empiric”) treatment. The goal is to see which works better and more safely as a rescue plan.
TaipeiAges 20 years+ - NCT05266807RecruitingPhase 3
Capsule fecal transplant to prevent C. difficile coming back
This study tests whether taking a capsule form of fecal microbiota transplant (FMT) can help adults with their first C. difficile infection—or a first relapse—get better and reduce repeat episodes. Participants also take specific antibiotics for C. difficile as part of the study process.
Basel, BaselAges 18 years+ - NCT05219110Recruiting
More fluids for children sick with toxin E. coli
This study looks at whether giving extra (hyper) fluids early helps children with a high-risk E. coli stomach infection. The goal is to improve outcomes by supporting the kidneys during the illness.
Birmingham, AlabamaAges 9 months–21 years - NCT05234723Recruiting
CMV Infection Treatment Outcomes in Transplant Patients
This study tracks how well ganciclovir (an antiviral medicine) works in transplant recipients who develop a resistant CMV infection. Researchers will review medical records to understand treatment success and patient outcomes.
Houston, TexasAges 18 years+ - NCT05244967Recruiting
Study of sexually transmitted infections and female fertility impact
This study looks at how sexually transmitted infections affect female fertility. It mainly enrolls young adults to better understand patterns and outcomes over time.
LübeckAges 18–22 - NCT05143307Enrolling by invitationPhase 1
Follow-up study for adults who received EBT-101 for HIV
This study checks how adults are doing long-term after receiving an HIV treatment called EBT-101 in an earlier study. It helps researchers understand safety and longer-term effects over time.
San Francisco, CaliforniaAges 18 years+ - NCT05147519Recruiting
Observes HIV and other infections to learn who gets them
This is an observational study that follows people to better understand how HIV and other infections (like sexually transmitted infections) happen and change over time. It may help researchers improve prevention and care, but it is mainly for monitoring rather than testing a new treatment.
Kericho, Kericho CountyAges 14–55 - NCT05141058RecruitingPhase 1
T cell therapy to help prevent COVID-19 after transplant
This Phase 1 trial tests a donated immune-cell treatment (T cells) to help immunocompromised people fight or resist COVID-19 after they recently received a bone marrow or stem cell transplant. It aims to see if the treatment is safe and if it helps the body respond better to the virus.
Washington D.C., District of ColumbiaAges 2–80 - NCT05164744Recruiting
MRI study of heart tissue changes after COVID-19
This study uses a heart MRI to look for leftover (healing) changes in heart tissue after COVID-19. It may help researchers better understand what ongoing heart effects can happen after infection.
Brooklyn, New YorkAges 18 years+ - NCT05159739Enrolling by invitation
Study of family genetic risk for joint implant infections
This study looks at whether certain families have a higher genetic risk for infections around joint implants. It may help researchers understand who is more at risk and how to prevent these infections.
Salt Lake City, UtahAges 18–100 - NCT05069688RecruitingPhase 1
Testing dolutegravir dosing in HIV and TB children
This study looks at the right way to dose dolutegravir (an HIV medicine) in young children who also have active tuberculosis (TB). Doctors will measure how the medicine moves through the body, especially when standard vs higher-dose rifampicin is used.
Ibadan, Oyo StateAges 4 weeks–5 years - NCT05051098Recruiting
Registry for people with hepatitis B infection
This study is a registry, meaning it collects health information from people living with hepatitis B rather than giving a new treatment. It may help researchers better understand different hepatitis B groups and outcomes over time.
HanoverAges 18 years+
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Common questions
- Are there clinical trials for infections?
- Yes. Clin2 currently lists 1,666 recruiting infections studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a infections trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a infections trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.