Clinical trials · Chicago, IL
Infectious Disease clinical trials in Chicago
We’re tracking 27 recruiting infectious disease studies with a site in or near Chicago — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Chicago
- NCT07069400Recruiting
Observational study of adults with acute infection
This study observes adults hospitalized with a new or recent infection (symptoms started within 30 days). The goal is to learn more about how infections affect people in the hospital, without testing any new drugs or treatments.
Chicago, IllinoisAges 18 years+ - NCT05719441RecruitingPhase 2
Testing HIV antibodies plus early HIV treatment for possible remission
This trial tests whether giving two powerful HIV-fighting antibodies (called broadly neutralizing monoclonal antibodies) along with starting standard HIV medications soon after infection can help control the virus without needing daily pills. If successful, it might allow people to take a 'treatment pause' while keeping their immune system healthy.
Chicago, IllinoisAges 18–70 - NCT06517693RecruitingPhase 1
HIV antibody safety study for newborns at risk
This study tests whether giving a combination of two lab-made antibodies (PGT121.414.LS and VRC07-523LS) to newborns exposed to HIV during pregnancy is safe and how the body processes them. It may help protect infants from getting HIV after birth.
Chicago, IllinoisAges Up to 3 days - NCT05201469RecruitingPhase 2
VIB4920 for lupus kidney inflammation not responding well enough
This Phase 2 study tests VIB4920 to treat active lupus nephritis, a type of kidney disease caused by lupus. It may help reduce kidney inflammation and improve kidney outcomes in people with active disease despite standard care.
Chicago, IllinoisAges 18 years+ - NCT00004317RecruitingPhase 4
Treating Congenital Toxoplasmosis With Three Medications
This study tests a combination of three medications (pyrimethamine, sulfadiazine, and leucovorin) to treat toxoplasmosis—a parasitic infection passed from mother to baby during pregnancy. The goal is to see if early treatment prevents serious complications in infected infants.
Chicago, IllinoisAges Any age - NCT06075745RecruitingPhase 2
CMV Vaccine Study for Liver Transplant Candidates
This trial tests a vaccine to prevent cytomegalovirus (CMV) infection in people awaiting a first liver transplant. You may be eligible if you have never been infected with CMV and are scheduled to receive a liver transplant within the next 1 to 12 months.
Chicago, IllinoisAges 18 years+ - NCT06004739Recruiting
Antibiotics for older adults with delirium and abnormal urine tests
This trial tests whether giving antibiotics helps older adults in the hospital who have delirium (sudden confusion) and signs of bacteria in their urine but no clear urinary infection. It aims to see if treatment can improve confusion and avoid unnecessary antibiotics.
Chicago, IllinoisAges 60 years+ - NCT07040319RecruitingPhase 1/Phase 2
Hepatitis C treatment study for pregnant women
This study tests a medicine called glecaprevir/pibrentasvir for pregnant women with hepatitis C, with or without HIV. It aims to see how the medicine works in the body and if it is safe during pregnancy.
Chicago, IllinoisAges 16–45 - NCT07108387RecruitingPhase 2
Stopping or reducing tocilizumab for well-controlled giant cell arteritis
This study compares stopping tocilizumab (Actemra) completely versus reducing the dose in people whose giant cell arteritis has been well controlled for at least a year. The goal is to find out which approach keeps the disease in remission while reducing medication side effects.
Chicago, IllinoisAges 50 years+ - NCT06034080Recruiting
Cutting down unneeded antibiotics for children's ear infections
This study tests ways to help doctors avoid prescribing antibiotics when they are not needed for children with ear infections. If you are a parent of a child diagnosed with an ear infection or a healthcare provider, you may be able to join different parts of the study.
Chicago, IllinoisAges 6 months–17 years - NCT01186913Enrolling by invitation
Natural history study for severe combined immune deficiency (SCID)
This study follows children and adults with SCID and related immune disorders to understand how the illness behaves over time. It also helps researchers learn which testing results and genetic types of SCID match different treatment plans.
Chicago, IllinoisAges Any age - NCT07279467Recruiting
Peanut allergy food challenge biomarker study
This study aims to identify markers in the blood that could help predict how severe a peanut allergy reaction might be. If you qualify, your child will undergo a supervised peanut challenge to see how their body responds.
Chicago, IllinoisAges 1–17 - NCT06136091Recruiting
Asthma study in select communities using a smartphone app
This study looks at how asthma affects people in certain communities and tests a new way to manage it using a smartphone app. It is for people with long-standing asthma and those without asthma, to compare their health over time.
Chicago, IllinoisAges 6–17 - NCT07549503RecruitingPhase 2
Liver Transplant Immune Changes Study
This research study tracks early signs of immune system changes in children who received a liver transplant 3–7 years ago and are doing well. By studying blood and liver samples, researchers hope to better understand how to prevent rejection and improve long-term transplant survival.
Chicago, IllinoisAges 3–13 - NCT07342491RecruitingPhase 1
Testing dasatinib to shrink HIV reservoir
This trial tests whether the drug dasatinib can reduce the hidden HIV reservoir in people who have had their virus well-controlled on HIV medications for a long time. It may help move toward a cure by targeting the cells where HIV hides.
Chicago, IllinoisAges 18 years+ - NCT05947071RecruitingPhase 2
Higher-dose flu vaccine versus standard dose in child transplant patients
This trial compares a higher-dose flu vaccine to the standard dose in children who recently received a kidney, heart, and/or liver transplant. It aims to see which dose better protects children against influenza while checking for safety.
Chicago, IllinoisAges 3–17 - NCT06504160RecruitingPhase 1
Testing a bacteria cream for eczema (TIME-2)
This study tests whether a cream made from a friendly skin bacteria (Staphylococcus hominis) can help treat eczema. Eligible participants will apply the cream to eczema patches on their arms, legs, or trunk for several weeks.
Chicago, IllinoisAges 6 years+ - NCT06919003RecruitingPhase 2
Improving kidney transplant with a single injection of a protective protein
This trial tests whether a single injection of C1 esterase inhibitor into a donated kidney during preservation can improve transplant outcomes. It is for adults on dialysis waiting for a deceased-donor kidney who meet specific blood and tissue matching requirements.
Chicago, IllinoisAges 18–75 - NCT06918990RecruitingPhase 1
CarBel for antibody-mediated rejection after kidney transplant
This study tests a new drug called CarBel to treat antibody-mediated rejection in kidney transplant patients. The goal is to see if it can help stop the rejection and protect your new kidney.
Chicago, IllinoisAges 18–75 - NCT06280950RecruitingPhase 2
Lowering immunosuppression after liver transplant with everolimus
This study tests whether adding the drug everolimus can safely reduce the amount of tacrolimus (an anti-rejection medicine) needed after a first liver transplant. This may help protect your kidneys while still preventing organ rejection.
Chicago, IllinoisAges 18 years+ - NCT02140255RecruitingPhase 1/Phase 2
Intensive early HIV treatment in newborns to aim for remission
This study gives very early, intensive HIV medicine to infants diagnosed with HIV and follows them closely to see if HIV can go into remission (stop being detectable without ongoing treatment). It may help families understand whether treating right after birth can change a child’s long-term HIV outlook.
Chicago, IllinoisAges Up to 2 days - NCT06055608RecruitingPhase 2
Improving kidney transplant outcomes in teens and young adults
This trial tests a new approach to help teenagers and young adults keep their first kidney transplant working well. It looks at how to improve long-term success by carefully managing the immune system around the time of transplant.
Chicago, IllinoisAges 13–20 - NCT05272241Recruiting
Asthma registry that helps researchers learn about asthma
This study enrolls people in specific cities to collect health information that helps researchers better understand asthma and how to recruit future studies. It may help by improving knowledge about asthma types and care in real-world settings.
Chicago, IllinoisAges Any age - NCT07103746RecruitingPhase 2
Ublituximab for antibody-positive IMNM
This study tests an investigational medication called ublituximab (an infusion) for people with a rare autoimmune muscle disease called IMNM. It aims to reduce muscle weakness and damage by targeting specific immune cells (B cells). To join, you need a recent diagnosis (within 1 year), specific antibodies, and be on limited other medications.
Chicago, IllinoisAges 18 years+
Hear when a new Infectious Disease trial opens near Chicago, IL
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Where these studies are running near Chicago
Institutions with a site for the recruiting infectious disease studies listed above.
- Ann & Robert H. Lurie Children's Hospital of Chicago · 4 studies
- Northwestern University · 3 studies
- Ann & Robert H. Lurie Children's Hospital of Chicago: Division of Allergy and Immunology · 2 studies
- University of Chicago, Department of Medicine: Rheumatology · 2 studies
- 32515, Rush Univ./Cook County Hosp. Chicago CRS
- 4001, Lurie Children's Hospital of Chicago Clinical Research Site
- 5083, Rush University Cook County Hospital Clinical Research Site
- AllianceChicago
What taking part in a infectious disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting infectious disease studies in Illinois.
Common questions
- Are there infectious disease clinical trials near Chicago?
- Yes. We're currently tracking 27 recruiting infectious disease studies with a site near Chicago, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a infectious disease study near Chicago?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Chicago to take part?
- Not necessarily. These studies have a site near Chicago, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a infectious disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New infectious disease studies open near Chicago regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.