Clinical trials
Injection Drug Use clinical trials
Below are recruiting injection drug use clinical trials, each written for real people, not researchers. We’re tracking 81 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06829238RecruitingPhase 4
Metformin to boost immune function in people with a history of drug use
This study tests whether metformin, a common diabetes drug, can help restore immune system balance in people who have used injection drugs in the past. It includes both people living with HIV and those who are HIV-negative.
Birmingham, AlabamaAges 18–64 - NCT06103370Recruiting
HIV prevention via telemedicine and peer networks
This study tests how well a program combining telemedicine (virtual doctor visits) and peer support can help prevent HIV among people who inject drugs. You'd get trained, attend weekly group sessions, and invite a friend or partner to also take part.
Baltimore, MarylandAges 18 years+ - NCT06513156Recruiting
Care support for hospitalized patients with drug-related infections
This study is for people who are in the hospital with a serious infection caused by injection drug use. It aims to provide better care and support while you are in the hospital and after you leave.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07199335RecruitingPhase 4
Injectable HIV prevention drug for people who inject drugs
This study tests a long-acting injectable medication called cabotegravir to prevent HIV in people who inject drugs. If you have injected street drugs recently, you may be able to get this shot every few months instead of taking daily pills.
Boston, MassachusettsAges 18 years+ - NCT07518238Enrolling by invitationPhase 2
Pain Relief Methods for Abdominal Wall Surgery
This study compares two different pain-relief injection techniques (BDE and Exparel) given during abdominal wall reconstruction surgery to see which works better at reducing pain and opioid use after surgery. You would receive one of these injections as part of your anesthesia care.
Dallas, TexasAges 18 years+ - NCT06541028Recruiting
Quick-start HIV treatment study for people who inject drugs
This study tests a rapid-start antiretroviral therapy (ART) approach for people who inject drugs and have HIV. The goal is to see if starting HIV medicine quickly helps reduce stigma and improve health outcomes.
KajangAges 18 years+ - NCT07625917Recruiting
Testing an online HIV prevention program for people who inject drugs
This study tests whether an internet-based HIV prevention program works for people who use injection drugs. Researchers want to see if online tools can help reduce HIV risk and improve health outcomes.
The Bronx, New YorkAges 18 years+ - NCT06953479RecruitingPhase 4
Hepatitis C treatment for people awaiting trial in jail
This study offers a once-daily pill (Epclusa) to treat hepatitis C for people in jail who have never taken HCV medicine before. The goal is to see if starting treatment while incarcerated and continuing after release can cure the infection.
Cranston, Rhode IslandAges 18 years+ - NCT05454787Recruiting
Testing Ondexxya for emergency reversal of blood thinners
This study looks at Ondexxya, a medicine used to reverse the effect of certain blood thinners during a dangerous bleeding emergency. It may help doctors better understand how to manage life-threatening bleeding caused by apixaban, rivaroxaban, or edoxaban.
AichiAges Any age - NCT06545877Recruiting
Survey of REKOVELLE for fertility treatment
This survey collects information from people who have already used REKOVELLE (a medication that helps the ovaries produce eggs) as part of their fertility treatment. Taking part will help researchers learn how the medication works in real-world daily practice.
Omitama, IbarakiAges Any age - NCT06395129Recruiting
Better syringes for people who inject drugs
This study provides safer, low-dead-space syringes to people who inject drugs to help reduce the spread of infections like HIV and hepatitis C. It is designed for people in low- and middle-income countries who use needle exchange programs.
YerevanAges 18 years+ - NCT05342493Recruiting
Survey study of long-term Ajovy injections
This is a study that collects information about how people use Ajovy (a medication for migraine) over time by injection. It mainly looks at safety and real-world use, and it may help researchers understand long-term treatment needs.
OsakaAges 18 years+ - NCT05679284Recruiting
Study for retained needle fragments in people who inject drugs
This observational study looks at whether small pieces of drug-injection needles remain in injection sites. You may help by answering a questionnaire and getting X-ray images, which could improve how care and safety are handled for people who inject drugs.
TampereAges 18 years+ - NCT07386587Enrolling by invitationPhase 3
Methotrexate plus etanercept for juvenile arthritis
This study compares methotrexate alone versus methotrexate combined with etanercept to see which works better for children with polyarticular juvenile idiopathic arthritis. The goal is to help children achieve low disease activity quickly.
Lahore, Punjab ProvinceAges 2–16 - NCT05669534RecruitingPhase 4
HIV prevention support for people starting PrEP
This study tests how to better support HIV prevention for people who inject drugs and are newly starting PrEP (medicine to prevent HIV). It focuses on people taking medication for opioid use disorder and who have mild thinking and memory problems, to help them stay safe and adhere to prevention.
New Haven, ConnecticutAges 18 years+ - NCT05769218Recruiting
Rapid HIV prevention and opioid treatment access for people who inject
This study helps people who inject drugs start HIV prevention (PrEP) and medication for opioid use disorder (MOUD) faster. It may reduce HIV risk and improve access to treatment, while the study checks whether the “rapid access” approach works.
Boston, MassachusettsAges 18 years+ - NCT05367635RecruitingPhase 1
Testing a new drug for advanced stomach cancers with CLDN18.2
This Phase 1 study tests SKB315 to treat advanced solid tumors, with special focus on stomach/gastroesophageal junction cancer that has high CLDN18.2 in tumor tissue. It may help you if standard treatments have not worked or are not available, though early-phase studies mainly look at safety and the best way to dose.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT07785934RecruitingPhase 1
Testing a new weight management injection for drug interactions
This study tests a new injectable medication for weight management in people with overweight or obesity. It investigates how the drug interacts with other medications and checks its safety. Participation requires a 6-month commitment with regular study visits.
Hefei, AnhuiAges 18–45 - NCT07128888RecruitingPhase 1
GZR18 injection effects on stomach emptying and drug interactions
This trial tests how a new injectable drug, GZR18, affects how fast your stomach empties and how it interacts with other medicines. It is for obese Chinese adults who want to join a research study.
BeijingAges 18–50 - NCT06139666Enrolling by invitationPhase 4
Liposomal bupivacaine nerve block for rotator cuff surgery
This study tests whether a long-lasting numbing medicine called liposomal bupivacaine (Exparel) works better than standard pain relief for people having rotator cuff surgery. It aims to lessen pain after surgery so you may need fewer pain pills.
Camden, New JerseyAges 18 years+ - NCT06474442RecruitingPhase 2
BD111 gene therapy for herpes simplex virus eye infection
This trial tests a new gene therapy called BD111 for people with a herpes simplex virus infection in the cornea (the clear front part of the eye). It aims to see if the treatment is safe and can help clear the virus, possibly improving vision.
Wenzhou, ZhejiangAges 18–70 - NCT07541131Enrolling by invitation
Reducing HIV stigma to improve treatment access for drug users
This study tests whether reducing stigma and discrimination against people who use drugs can help more people access HIV treatment and prevention. You would participate in peer-led group sessions and surveys over 18 months to help researchers understand how stigma affects treatment access in Bishkek.
BishkekAges 18 years+ - NCT05769023Enrolling by invitation
Pilot test targeting HIV prevention for people who inject drugs
This pilot program studies where HIV risk is highest and uses that information to decide how prevention efforts should be delivered. If you’ve used opioids recently and you inject drugs, you may be invited to participate to help reduce HIV risk.
Baltimore, MarylandAges 18 years+ - NCT07225816RecruitingPhase 1
How fasting affects stomach food with GLP-1 drugs
This study looks at how long fasting and temporarily stopping certain diabetes or weight-loss medications (like semaglutide or liraglutide) affects how much food stays in your stomach. It may help understand how these medications work in people who are overweight.
Cypress, CaliforniaAges 18 years+
Hear when a new Injection Drug Use trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for injection drug use?
- Yes. Clin2 currently lists 81 recruiting injection drug use studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a injection drug use trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a injection drug use trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.