Clinical trials
Drug Use clinical trials
Below are recruiting drug use clinical trials, each written for real people, not researchers. We’re tracking 157 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05534568Recruiting
Parent support program for families affected by pregnancy substance use
This program aims to help mothers and young children get safer, better support services when substance use occurred during pregnancy. It may help connect you (or your child) to the right community resources and reduce risk of ongoing alcohol or drug exposure.
Oklahoma City, OklahomaAges 18 years+ - NCT06103370Recruiting
HIV prevention via telemedicine and peer networks
This study tests how well a program combining telemedicine (virtual doctor visits) and peer support can help prevent HIV among people who inject drugs. You'd get trained, attend weekly group sessions, and invite a friend or partner to also take part.
Baltimore, MarylandAges 18 years+ - NCT06163651Recruiting
Parent-child support program for parents of young children
This trial tests a one-year program to help parents with young children. It offers support and resources to strengthen your family.
Enid, OklahomaAges 18 years+ - NCT07433712Recruiting
Project REACH: telehealth support for people who use drugs
This trial uses video calls and telehealth to connect people who use drugs with health services and support. The goal is to make it easier to get care and stay healthy.
Minneapolis, MinnesotaAges 18 years+ - NCT07466784Recruiting
Opioid use registry for emergency patients
This study is for people who come to the emergency department because of an opioid overdose, withdrawal, or related problem. It will collect information about patients' experiences to help improve care and support for opioid use.
Vancouver, British ColumbiaAges Any age - NCT06498167Recruiting
Rinvoq safety study
This study is checking the safety of the medicine Rinvoq (upadacitinib) in people who have been prescribed it. It involves answering a few questions over the phone to help doctors understand how the medicine is working for you.
PortoAges 18 years+ - NCT07199335RecruitingPhase 4
Injectable HIV prevention drug for people who inject drugs
This study tests a long-acting injectable medication called cabotegravir to prevent HIV in people who inject drugs. If you have injected street drugs recently, you may be able to get this shot every few months instead of taking daily pills.
Boston, MassachusettsAges 18 years+ - NCT06689228Enrolling by invitation
Education and monitoring to improve drug use in dialysis patients
This study tests whether a special education program and remote monitoring can help hemodialysis patients use their medications more safely. It is designed for people who have been on dialysis for at least six months.
Burdur, BucakAges 18 years+ - NCT06829238RecruitingPhase 4
Metformin to boost immune function in people with a history of drug use
This study tests whether metformin, a common diabetes drug, can help restore immune system balance in people who have used injection drugs in the past. It includes both people living with HIV and those who are HIV-negative.
Birmingham, AlabamaAges 18–64 - NCT07312591Recruiting
Using a phone app to follow up on college students’ drug use
This study tests whether using a smartphone app called LINE@ can help follow up with college students who have used illegal drugs. The goal is to provide support and see how well the app works for staying in touch.
Taipei, Heping E. RdAges 18 years+ - NCT06513156Recruiting
Care support for hospitalized patients with drug-related infections
This study is for people who are in the hospital with a serious infection caused by injection drug use. It aims to provide better care and support while you are in the hospital and after you leave.
Washington D.C., District of ColumbiaAges 18 years+ - NCT04814212Recruiting
Testing a drug-coated balloon for people with bleeding risk
This trial looks at whether a “drug-coated balloon” used during a heart procedure (PCI) is safer or better for people who are at higher risk of bleeding while on blood thinners. It may help reduce complications around the time of the procedure in people like you.
Jyväskylä, Central FinlandAges 18 years+ - NCT06693960RecruitingEarly Phase 1
Oregano and drug interaction study
This study looks at how oregano affects the way your body processes certain medications. It might help patients understand if oregano can change how drugs work.
Spokane, WashingtonAges 18–64 - NCT05380765Recruiting
Help for First Nation teens to prevent substance use
This trial tests a positive, prevention-focused approach to help North American Indian (First Nation) teens make healthier choices about substance use. It involves both teens and an adult family member who supports good decision-making.
Kingston, Rhode IslandAges 10–14 - NCT05679284Recruiting
Study for retained needle fragments in people who inject drugs
This observational study looks at whether small pieces of drug-injection needles remain in injection sites. You may help by answering a questionnaire and getting X-ray images, which could improve how care and safety are handled for people who inject drugs.
TampereAges 18 years+ - NCT06324786Recruiting
Brain training to reduce alcohol, cannabis, and tobacco use
This study tests whether a type of brain training called neurofeedback can help people reduce their use of alcohol, cannabis, and cigarettes. If you're an adult who uses all three heavily and have no other mental health conditions, you may be eligible.
Phoenix, ArizonaAges 18 years+ - NCT05829655RecruitingEarly Phase 1
Measuring drug cravings in people with opioid use disorder
This study tests whether the medication suvorexant can reduce drug cravings in people with opioid use disorder. You will take either suvorexant or a placebo and have your cravings measured in a safe setting.
Baltimore, MarylandAges 18–65 - NCT06541028Recruiting
Quick-start HIV treatment study for people who inject drugs
This study tests a rapid-start antiretroviral therapy (ART) approach for people who inject drugs and have HIV. The goal is to see if starting HIV medicine quickly helps reduce stigma and improve health outcomes.
KajangAges 18 years+ - NCT06712602RecruitingPhase 1
Testing PT150 for Alcohol Use Disorder
This study tests whether a drug called PT150 can help people with moderate to severe alcohol use disorder who are not currently seeking treatment. You will be asked to stay abstinent from alcohol for short periods and attend sessions to see how PT150 affects your body and alcohol cravings.
Lexington, KentuckyAges 21–55 - NCT07527871Enrolling by invitation
Emergency care screening and counseling for substance use prevention
This study tests whether screening patients in the emergency department for substance use, followed by a brief counseling session, can help prevent substance use problems and overdoses. You would be asked about your substance use and receive supportive counseling by phone or video.
Columbus, OhioAges 18 years+ - NCT07386587Enrolling by invitationPhase 3
Methotrexate plus etanercept for juvenile arthritis
This study compares methotrexate alone versus methotrexate combined with etanercept to see which works better for children with polyarticular juvenile idiopathic arthritis. The goal is to help children achieve low disease activity quickly.
Lahore, Punjab ProvinceAges 2–16 - NCT06967831Recruiting
Testing existing drugs for mitochondrial disorders
This trial looks at whether drugs already approved for other conditions might help people with Leigh syndrome, a rare mitochondrial disorder. Researchers will study cells made from your skin to see how these drugs work.
Düsseldorf, North Rhine-WestphaliaAges Any age - NCT06880705Recruiting
Trans-Led Care Study for alcohol and drug support
This study is testing a program designed by and for transgender adults to help with alcohol or drug use problems. It looks at whether a supportive, community-based approach can improve health and well-being.
Chicago, IllinoisAges 18 years+ - NCT07460973Recruiting
Wellness program for American Indian youth
This study tests a program designed to improve health and reduce disparities for American Indian youth ages 12–18. It includes educational activities and cultural teachings.
Bozeman, MontanaAges 12–18
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Common questions
- Are there clinical trials for drug use?
- Yes. Clin2 currently lists 157 recruiting drug use studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a drug use trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a drug use trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.