Clinical trials
Drug-drug Interaction clinical trials
Below are recruiting drug-drug interaction clinical trials, each written for real people, not researchers. We’re tracking 27 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07809789RecruitingPhase 1
Vorolanib drug interaction study in healthy volunteers
This study checks how the experimental cancer drug vorolanib interacts with other medicines when taken together. It is for healthy people to help find the right dose and safety information before it is tested in patients.
Hangzhou, ZhejiangAges 18–45 - NCT07809815RecruitingPhase 1
Drug interaction study of befotertinib in healthy volunteers
This study checks how befotertinib, an experimental cancer drug, interacts with other drugs in healthy people. It helps make sure the drug is safe and works well when taken with other medicines.
Hangzhou, ZhejiangAges 18–45 - NCT07785934RecruitingPhase 1
Testing a new weight management injection for drug interactions
This study tests a new injectable medication for weight management in people with overweight or obesity. It investigates how the drug interacts with other medications and checks its safety. Participation requires a 6-month commitment with regular study visits.
Hefei, AnhuiAges 18–45 - NCT07783503RecruitingPhase 1
Drug interaction study of pelabresib in healthy adults
This study tests how two other drugs affect the levels of the study drug pelabresib in healthy people. It aims to see if taking these drugs together changes how the body processes pelabresib.
NottinghamAges 18–55 - NCT07766369RecruitingPhase 1
Drug interaction study for healthy adults
This trial tests how a new drug, E2086, interacts with other medicines in healthy volunteers. It helps make sure the drug is safe and works properly when combined with common medications.
Austin, TexasAges 18–55 - NCT07682948RecruitingPhase 1
Drug interaction study of UIC202601 and UIC202602 in healthy volunteers
This trial tests how two experimental drugs, UIC202601 and UIC202602, interact with each other in the body. Healthy volunteers take both drugs to check for side effects and how the body processes them.
Anyang, Manan-guAges 19–54 - NCT07652723RecruitingPhase 1
How a new blood-clotting drug affects clotting with and without aspirin
This study tests an experimental drug (BAY3389934) to see how it affects blood clotting and if it's safe. It is given to healthy adults, alone and then with aspirin. It will help researchers understand how the drug works before testing in patients.
Miami, FloridaAges 18–55 - NCT07629999RecruitingPhase 1
Safety study of experimental drug BMS-986533 in healthy people
This early-stage study tests how a new experimental drug (BMS-986533) is processed and tolerated by healthy volunteers. Researchers will also check how food and stomach acid affect the drug, and whether it interacts with other medications.
Lincoln, NebraskaAges 18–55 - NCT07620041RecruitingPhase 1
Testing QLC5508, a new cancer drug, in advanced solid tumors
This early-stage trial tests QLC5508, an experimental cancer medication, in patients with advanced solid tumors that haven't responded to standard treatments. The study focuses on safety, how the drug moves through your body, and potential interactions with other medications.
Changchun, JilinAges 18 years+ - NCT07550816RecruitingPhase 1
Safety study of ZT002 injection in overweight adults
This study tests how a new diabetes medicine called ZT002 works in the body and whether it interacts safely with other common medications. Researchers will monitor healthy volunteers who are overweight to understand the medicine's safety and effectiveness.
Chengdu, SichuanAges 18–45 - NCT07516548Recruiting
Long-acting HIV prevention and birth control study
This research studies how two types of long-acting birth control (a shot called cabotegravir and an implant) work in your body after pregnancy, and how they interact with HIV prevention or treatment. The study helps doctors understand the best doses and timing for women like you.
Bontleng, GaboroneAges 18 years+ - NCT07454291RecruitingPhase 1
How taladegib works in healthy volunteers
This trial is for healthy volunteers to see how the study drug taladegib (ENV-101) interacts with other medicines in the body. It will help researchers understand how the drug is absorbed and processed, which is important for future studies in patients.
Brisbane, QueenslandAges 26–65 - NCT07402915RecruitingPhase 1
Study of AZD5335 with itraconazole in ovarian cancer
This study tests how the body handles the study drug AZD5335 when taken with itraconazole (a common antifungal). It is for people with platinum-resistant ovarian, primary peritoneal, or fallopian tube cancer who have already tried standard treatments.
BatumiAges 18 years+ - NCT07367971RecruitingPhase 1
ABP-671 interaction study for gout patients
This study tests how a new drug, ABP-671, interacts with allopurinol (a common gout medicine) in people with gout. It is looking for participants with normal or moderately reduced kidney function.
Cary, North CarolinaAges 18–75 - NCT07340190RecruitingPhase 1
How pelabresib affects other drugs in advanced cancer
This study tests how a new drug (pelabresib) interacts with other medicines like diabetes pills, a sedative, and birth control pills. It is for people with advanced cancer to help understand safe dosing.
BordeauxAges 18 years+ - NCT07331389RecruitingPhase 1
How HDM1002 interacts with common drugs and diabetes medications
This study tests how a new drug called HDM1002 interacts with common diabetes medications (metformin, empagliflozin) and other drugs like warfarin and valsartan. If you are a generally healthy adult (age 18-45) with a higher BMI, this trial helps ensure the new drug is safe when taken with other medicines.
HefeiAges 18–45 - NCT07314346RecruitingPhase 1
Study of a new hepatitis C drug with addiction medications
This study checks how a new hepatitis C medicine (bemnifosbuvir/ruzasvir) interacts with medications used for opioid addiction, such as buprenorphine/naloxone or methadone. It helps doctors understand if the new medicine is safe and effective for people taking these addiction treatments.
Hollywood, FloridaAges 18–65 - NCT07251153RecruitingPhase 1
Comparing two forms of vonafexor in healthy volunteers
This study compares two forms of an experimental drug called vonafexor to see how they work in the body and if they interact with other medications. It's for healthy volunteers to make sure the drug is safe before testing in patients with liver disease.
GièresAges 18–65 - NCT07128888RecruitingPhase 1
GZR18 injection effects on stomach emptying and drug interactions
This trial tests how a new injectable drug, GZR18, affects how fast your stomach empties and how it interacts with other medicines. It is for obese Chinese adults who want to join a research study.
BeijingAges 18–50 - NCT07100054Enrolling by invitation
Genetic markers for CDK4/6 inhibitor therapy in breast cancer
This trial looks at how genetic markers and other substances in your blood might help personalize treatment with CDK4/6 inhibitors, a targeted therapy for breast cancer. It aims to find better ways to predict which patients will benefit most.
London, OntarioAges 18 years+ - NCT06865885RecruitingPhase 4
Lowering cholesterol with inclisiran in people on many medications
This study tests a new injectable medicine called inclisiran for people who are already on many medications and have high cholesterol. It is designed for those who cannot lower their cholesterol enough with statins, especially if they have diabetes or other heart risks.
La Jolla, CaliforniaAges 18–85 - NCT05830279Recruiting
Personalized drug choices to better manage cancer treatment side effects
This trial tests a personalized approach to selecting drugs during cancer treatment. The goal is to improve how well your prescribed medicines work for symptoms and side effects while keeping you safe.
London, OntarioAges 18 years+ - NCT06733675RecruitingPhase 1
Safety study of a new antibiotic combination
This trial tests a new antibiotic called ceftibuten-ledaborbactam in healthy volunteers to see if it is safe and how the body processes it. You may join if you are a healthy adult and do not have allergies to certain antibiotics.
Lenexa, KansasAges 18–55 - NCT05789173RecruitingEarly Phase 1
Testing how genetics affect drug levels with methadone
This early study tests how a person’s genetic makeup may change how fast certain medicines move through the body. It compares drug levels when combined with methadone and tizanidine, aiming to understand safer dosing and effects.
Indianapolis, IndianaAges 18–65
Hear when a new Drug-drug Interaction trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for drug-drug interaction?
- Yes. Clin2 currently lists 27 recruiting drug-drug interaction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a drug-drug interaction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a drug-drug interaction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.