Clinical trials
Keratoconus clinical trials
Below are recruiting keratoconus clinical trials, each written for real people, not researchers. We’re tracking 36 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03918408RecruitingPhase 1
Platinum eye drops and light to slow keratoconus
This Phase 1 study tests whether a specific corneal cross-linking system (called PXL-Platinum 330) is safe and effective for people with progressive keratoconus, a condition that makes the cornea thin and bulge. The goal is to slow vision changes and see how well the treatment works in the short term.
Eugene, OregonAges 12–45 - NCT03922542RecruitingPhase 2/Phase 3
Compare faster versus standard corneal strengthening
This trial compares two ways to strengthen the cornea (the clear front surface of your eye) in people with keratoconus or corneal weakening after laser vision surgery. It may help determine whether an accelerated (faster) approach works as well and with acceptable safety.
Indianapolis, IndianaAges 10 years+ - NCT04094090RecruitingPhase 2
Corneal strengthening treatment for thinning eye shape
This Phase 2 study tests how safe and well a corneal cross-linking device (called PXL-Platinum 330) works for people with corneal ectasia (a thinning/steepening of the cornea). If you qualify, the goal is to help stop or slow further worsening of your cornea shape and improve eye stability.
San Francisco, CaliforniaAges 10 years+ - NCT04129021Recruiting
Eye imaging test with fast detailed scans
This trial studies whether a new, very high-resolution and high-speed eye scan can be used for people with eye problems or for healthy volunteers. It may help doctors better “see” eye structures more clearly to guide care.
ParisAges 18 years+ - NCT04251143Recruiting
Study for corneal disease and corneal thinning
This study looks at people with corneal disease, especially corneal thinning that can change how the eye focuses light. It may help researchers understand treatments and care plans for these conditions.
Dresden, SaxonyAges 18–65 - NCT04570020Recruiting
Check how well wide-view scans guide scleral lens fitting
This study tests whether a special wide-area eye scan (OCT) can help fit scleral contact lenses more accurately. It may help people who need scleral lenses because of certain cornea shape problems or after past eye surgeries.
Portland, OregonAges 18 years+ - NCT04741230Recruiting
Test implant for severe corneal thinning to avoid transplant
This study tests a procedure called Xenia corneal lenticule in people with severe keratoconus or severe post-LASIK corneal thinning who want to avoid a corneal transplant. It aims to improve vision while checking safety and how well the new procedure works over time.
Wolverhampton, West MidlandsAges 18–79 - NCT05516004RecruitingPhase 2
Cornea strengthening treatment study for thinning corneas
This Phase 2 study tests whether a procedure called PXL‑Platinum 330 can safely and effectively strengthen corneas that are thinning (such as keratoconus or related conditions). It aims to see if the treatment can help stabilize or improve the cornea’s shape while keeping side effects low.
Boca Raton, FloridaAges 18 years+ - NCT06565091Recruiting
Testing a new all-in-one eye measurement device
This study tests a new all-in-one device that measures several aspects of your eyes during a routine check-up. You just sit in front of it, no extra procedures. It's for both adults and children who already have an eye appointment.
RennesAges 4 years+ - NCT02118922Recruiting
Testing a light-scanning eye exam to diagnose corneal thinning
This study tests whether a special “Brillouin” microscope scan can spot corneal ectasia and related cornea conditions. It may help doctors diagnose problems earlier and better sort out who needs closer eye care.
Boston, MassachusettsAges 20–75 - NCT06751615Enrolling by invitation
Improving scleral lens fit with advanced imaging
This study tests whether using advanced imaging can help make scleral contact lenses fit better for people with certain eye conditions. If you have keratoconus, an irregular cornea after a transplant, or severe dry eye and have struggled with other lens types, this may be for you.
MadridAges 18 years+ - NCT06235567Enrolling by invitationPhase 1/Phase 2
Eye drop vs. insert for recovery after cornea crosslinking
This trial compares two ways to manage inflammation after corneal crosslinking for keratoconus: a tiny steroid insert placed in the tear duct versus standard steroid eye drops. It aims to see which option is easier and works just as well.
San Francisco, CaliforniaAges 13–64
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Common questions
- Are there clinical trials for keratoconus?
- Yes. Clin2 currently lists 36 recruiting keratoconus studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a keratoconus trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a keratoconus trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.