Clinical trials
Ketosis clinical trials
Below are recruiting ketosis clinical trials, each written for real people, not researchers. We’re tracking 15 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06699810RecruitingPhase 4
Understanding Diabetes Recovery After Severe Blood Sugar Crisis
This study looks at how certain people can recover from a dangerous blood-sugar emergency called DKA (diabetic ketoacidosis). Researchers want to understand why some patients improve and how to help them stay healthy long-term.
Atlanta, GeorgiaAges 18 years+ - NCT06867471Recruiting
Ketone drink study for kidney disease patients
This study tests if a ketone supplement can reduce protein in urine and protect kidney function in people with chronic kidney disease or polycystic kidney disease. You drink a special supplement and researchers measure how it affects your kidneys.
Herning, JutlandAges 18 years+ - NCT03991897Recruiting
Keto diet to treat early arm swelling after lymph node removal
This study tests whether a ketogenic (keto) diet can reduce arm lymphedema (swelling) that started within the last year after lymph node removal. It aims to improve swelling by changing the body’s metabolism.
LeuvenAges 18 years+ - NCT04219709Recruiting
Study how ketosis affects brain function in adults with type 1 diabetes
This study tests whether a “ketosis” state changes brain function in adults with type 1 diabetes. You may be asked to follow specific diet/food delivery plans and use devices that track glucose, which could help researchers understand how metabolism affects the brain.
Boston, MassachusettsAges 18–40 - NCT04275453RecruitingPhase 1/Phase 2
Test diet vs ketone drinks to reach ketosis safely
This early-stage study compares how quickly and effectively a low-carbohydrate diet versus taking ketone supplements helps the heart use less sugar (measured with PET/CT scans). It also looks at how long it takes to reach a “ketosis” state, which may be helpful for metabolic health.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05924295Recruiting
Study how ketone changes in the body with diet and fasting
This study looks at how your body processes “ketones,” which are energy molecules that rise with fasting or low carbohydrate intake. You may be asked to follow strict diet and activity rules before test days so researchers can see what affects ketone metabolism.
Novato, CaliforniaAges 20–70 - NCT06044935Recruiting
Nicotinamide riboside for fat burning and metabolism
This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) helps the body burn fat more efficiently during exercise. It may be a good option if you are overweight or have a specific type of diabetes (MODY2) and want to see if a natural supplement can boost your metabolism.
Bethesda, MarylandAges 18–65 - NCT06373016Recruiting
Ketone drink study for stable bipolar disorder
This study tests whether a ketone drink can change how the body uses energy in people with bipolar disorder. It may help understand new ways to manage the condition.
Belmont, MassachusettsAges 18–45 - NCT06559995RecruitingPhase 2/Phase 3
Ketone drink for alcohol withdrawal
This study tests whether a special ketone drink can ease alcohol withdrawal and help your brain heal. If you have been drinking heavily for at least 3 years and are having withdrawal symptoms now, this might be an option for you.
Philadelphia, PennsylvaniaAges 18–65 - NCT06590623Recruiting
How a ketone supplement affects your immune cells
This study tests what happens to your immune cells when you take a single dose of a common ingredient (ketone supplement) after not eating overnight. Researchers want to see if it changes how your immune system works at a molecular level.
Kelowna, British ColumbiaAges 19 years+ - NCT06596083Recruiting
Ketone supplement and altitude training study
This study tests whether drinking a ketone supplement helps your body adapt better during a 5-week altitude training program. You would live at high altitude but train at low altitude.
Leuven, Vlaams-BrabantAges 18–35 - NCT06815237RecruitingPhase 2/Phase 3
Ketone supplement and alcohol effects on brain metabolism
This study looks at how a ketone supplement and alcohol affect your brain's metabolism. You will be asked to visit the lab, have an MRI, and possibly take the supplement or drink alcohol.
Philadelphia, PennsylvaniaAges 21–65 - NCT07167693RecruitingPhase 1/Phase 2
Testing arginine for diabetic ketoacidosis in type 2 diabetes
This trial tests if an IV medicine called arginine hydrochloride can help manage diabetic ketoacidosis (DKA) in people with type 2 diabetes. It's for those who come to the ER with very high blood sugar and ketones.
Detroit, MichiganAges 18 years+ - NCT06937320Enrolling by invitationPhase 2
Testing ketone supplements for heart failure with preserved ejection fraction (HFpEF)
This study tests whether a special dietary supplement (ketone esters) can improve exercise ability and heart function in people with a type of heart failure where the heart pumps well but is stiff (HFpEF). You might join if you have stable symptoms, an ejection fraction of 50% or higher, and signs of fluid buildup in the heart.
Durham, North CarolinaAges 18 years+ - NCT06173973Enrolling by invitationPhase 2/Phase 3
Ketone supplement for alcohol withdrawal symptoms
This study tests whether a special supplement (ketones) can help people feel better during alcohol withdrawal. It is for adults who are already in a treatment program for alcohol withdrawal.
Philadelphia, PennsylvaniaAges 18–75
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Ketosis trials by city
Studies with a site in or near these metro areas.
Ketosis trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for ketosis?
- Yes. Clin2 currently lists 15 recruiting ketosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ketosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ketosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.