Clinical trials
Liver Resection clinical trials
Below are recruiting liver resection clinical trials, each written for real people, not researchers. We’re tracking 69 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02172651RecruitingEarly Phase 1
Vitamin D during early colon cancer or liver surgery
This trial studies whether taking higher-dose vitamin D3 around the time of colon cancer (or colon cancer with resectable liver metastases) surgery improves outcomes. It focuses on safety and possible effects on cancer-related health after surgery.
Boston, MassachusettsAges 18 years+ - NCT06621472Recruiting
Comparing two nerve blocks for liver surgery pain
This study compares two types of pain-relieving injections (nerve blocks) used during liver surgery. One is a retrolaminar block and the other is a subcostal transversus abdominis plane block. The goal is to see which one provides better pain control after surgery.
CairoAges 18–65 - NCT02886104Recruiting
Surgery versus local ablation for certain liver metastases
This trial compares two ways to treat colorectal cancer that has spread to the liver: removing liver tumors with surgery versus destroying them in place with local ablation. It may help doctors learn which approach works best for people whose disease can be fully treated and who have enough healthy liver left.
Guangzhou, GuangdongAges 18–80 - NCT05398380Recruiting
Liver transplant for colorectal liver cancer that can’t be removed
This trial studies liver transplantation for certain people with colorectal cancer that has spread only to the liver and cannot be removed with surgery. It aims to improve outcomes for carefully selected patients whose cancer is controlled on chemotherapy and who meet specific safety and scan requirements.
Barcelona, BarcelonaAges 18–70 - NCT06050252RecruitingPhase 2
Durvalumab plus chemo before surgery for high-risk bile duct cancer
This study tests whether adding the immunotherapy drug durvalumab to standard chemotherapy (gemcitabine and cisplatin) before surgery helps people with a high-risk type of bile duct cancer live longer. If you qualify, you would receive the drug combination before your planned surgery.
Irvine, CaliforniaAges 18 years+ - NCT05128890Recruiting
People who had prior pancreatic or liver surgery
This study looks back at people who previously had surgery to remove part of the pancreas or liver at a specific hospital. It aims to compare different resection (removal) techniques and how patients did afterward.
Dallas, TexasAges 18 years+ - NCT05062317RecruitingPhase 2
Blood test-guided chemotherapy after liver tumor removal
This trial uses a blood test (ctDNA, a sign of cancer cells shedding into the blood) to help guide chemotherapy after surgery to remove colorectal liver metastases. It may help patients get the right chemotherapy plan after their operation, potentially based on whether cancer material is still detectable.
Houston, TexasAges 18 years+ - NCT02920554Recruiting
Surgery comparison for T2–T3 gallbladder cancer
This study looks at whether a specific type of liver surgery (removing tissue in a wedge shape versus a different liver resection) improves outcomes for some patients with T2 or T3 gallbladder cancer. It may help decide the best surgical approach after the gallbladder has already been removed.
SuwonAges 19–80 - NCT07587216Recruiting
Liver Cancer Patient Database Study
This study builds a database of information from liver cancer patients treated at Tongji Hospital. Researchers will collect your medical records and treatment information to better understand liver cancer diagnosis and care over time.
Wuhan, HubeiAges 18 years+ - NCT06698146Recruiting
Liver transplant for colorectal cancer that spread to the liver
This trial tests a special approach for colorectal cancer that has spread to the liver: first removing the liver tumor, then doing a partial liver transplant, and later removing more liver tissue. The goal is to see if this can help people who otherwise have limited options.
Chicago, IllinoisAges 18 years+ - NCT07277322RecruitingPhase 1/Phase 2
Two immunotherapy drugs before surgery for MSS colorectal cancer with liver spots
This trial tests a combination of two immunotherapy drugs (Dupilumab and Toripalimab) before surgery for people with MSS colorectal cancer that has spread to the liver. The goal is to see if this treatment can shrink the liver tumors and help the body's immune system fight the cancer.
New York, New YorkAges 18 years+ - NCT07062380Recruiting
AI tool to predict liver cancer return after surgery
This study uses an AI tool to predict how liver cancer might come back after surgery. It is for people with early-stage liver cancer who are already scheduled for surgery and have recent MRI scans.
Wuhan, HubeiAges 18–75 - NCT05797077RecruitingPhase 3
After-surgery blood test–guided therapy for colon cancer liver spread
This Phase 3 trial tests whether an added “maintenance” treatment after liver surgery can help prevent colorectal cancer from coming back. It is only for people whose blood test (ctDNA) still shows signs of cancer after their operation.
Guangzhou, GuangdongAges 18–75 - NCT04796818Recruiting
MRI scan to track response in colorectal liver metastases
This study uses a special MRI scan to see how colorectal cancer in the liver responds to planned chemotherapy before and after surgery. It may help doctors better measure treatment success and plan care.
Houston, TexasAges 18 years+ - NCT06366048Recruiting
Liver surgery and risk of liver failure study
This study looks at how the amount of healthy liver tissue removed during surgery affects the risk of liver failure after the operation. It is for people with common types of liver cancer (HCC or ICC) who are having a planned liver resection.
Fujian, Shanghai MunicipalityAges Any age - NCT06420440RecruitingPhase 2
Pre-surgery treatment for liver cancer at high risk of return
This study tests a treatment given before surgery for liver cancer that is at high risk of coming back. You would receive a combination of chemotherapy directly into the liver artery (HAIC), a targeted pill (lenvatinib), and an immunotherapy drug (a PD-1 inhibitor) — if a computer model predicts you might benefit.
Xiangyang, HubeiAges 18–75 - NCT07282184RecruitingPhase 1/Phase 2
Liver cancer risk prediction and treatment study
This trial uses a computer model to predict if your liver cancer might come back aggressively after surgery. If you are at high risk, you may receive additional treatment before surgery to lower that risk.
Wuhan, HubeiAges 18–75 - NCT06856252Recruiting
Studying human liver organoids for a fatty liver disease called NASH
This study takes small samples of liver tissue to grow 3D 'mini livers' (organoids) in the lab. Researchers want to learn how non-alcoholic steatohepatitis (NASH), a serious fatty liver condition, starts and progresses, which could lead to better treatments.
Milan, MilanoAges 18 years+ - NCT06988852RecruitingPhase 2
Chemo infusion into liver for colorectal cancer spread
This trial tests a strong chemotherapy combination given directly into the liver's blood supply (called HAIC) for people whose colorectal cancer has spread only to the liver and cannot be removed with surgery yet. The goal is to shrink the liver tumors enough so they can be surgically removed.
Wuhan, HubeiAges 18–75 - NCT06311942RecruitingPhase 4
Comparing triple vs. dual therapy after liver surgery for liver cancer
This trial tests whether adding a third drug to standard two-drug therapy after liver surgery helps prevent liver cancer from returning. It is for people who have a specific blood vessel pattern in their tumor, called VETC, seen on a special stain.
Wuhan, HubeiAges 18–75 - NCT05705557Recruiting
Test of a clip system during open liver surgery
This trial studies a new clip system (ABSOLOK™) used during open liver operations. It aims to improve how surgeons control or manage parts of the liver during surgery.
Roma, RMAges 18 years+ - NCT04523701RecruitingPhase 3
Testing a “white test” to find bile ducts during liver surgery
This trial studies whether a simple “white test” using a special lipid (fat-like) solution can help the surgical team spot open bile ducts early during liver removal. Finding them sooner may help prevent bile leakage after liver surgery.
AarauAges 18 years+ - NCT05517811Recruiting
Blood test changes before and after cancer surgery
This study measures a blood test (TEG) before and after surgery to see how it changes in people with certain cancers. It may help doctors better understand recovery and risk around the time of surgery.
Aurora, ColoradoAges 18–99 - NCT05035108RecruitingEarly Phase 1
Bioartificial liver treatment using hiHep cells after liver surgery
This early-stage study tests a lab-made “bioartificial liver” (using hiHep cells) after major liver surgery to help the remaining liver recover. It may help people whose remaining liver volume after resection is less than half and who have acceptable heart, lung, and blood test results for surgery.
Hangzhou, ZhejiangAges 30–80
Hear when a new Liver Resection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for liver resection?
- Yes. Clin2 currently lists 69 recruiting liver resection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver resection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver resection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.