Clinical trials
Liver Transplantation clinical trials
Below are recruiting liver transplantation clinical trials, each written for real people, not researchers. We’re tracking 194 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06813508Recruiting
Liver cancer and transplant study for MASLD patients
This study looks at factors that predict liver cancer and the need for a liver transplant in people with a liver condition called MASLD (metabolic dysfunction-associated steatotic liver disease). The goal is to better understand the disease and improve care.
Bologna, BolognaAges 18 years+ - NCT06098547Recruiting
Liver transplant for bile duct cancer that can't be removed
This trial tests if a liver transplant can help people with a certain type of bile duct cancer (intrahepatic cholangiocarcinoma) that cannot be surgically removed. You must have had at least six months of chemotherapy and your cancer must be stable or smaller before you can be listed for a transplant.
PadovaAges 18–70 - NCT07365098Recruiting
Liver Transplant and the 30-Second Sit-to-Stand Test
This study looks at how well people waiting for a liver transplant can do a simple 30-second test of standing up and sitting down. The goal is to see if this test can help doctors understand your physical strength before surgery.
MalatyaAges 18–65 - NCT07685353Recruiting
Genes and graft fat after liver transplant study
This study looks at how genetic differences between liver donors and recipients affect fat buildup in the new liver after transplantation. It may help doctors understand why some transplanted livers develop steatosis (fatty liver) after the surgery.
New DelhiAges 18 years+ - NCT06125769Recruiting
Liver transplant for hard-to-treat bile duct cancer
This trial studies liver transplantation to treat a specific bile duct cancer (perihilar cholangiocarcinoma) that cannot be removed by surgery. It aims to see if a transplant can help when standard chemotherapy has kept the cancer stable.
Padova, PADOVAAges 18–70 - NCT07651748Enrolling by invitationPhase 1/Phase 2
Testing Secretin to Improve Donated Liver Quality
This trial tests whether adding a hormone called secretin to a machine that preserves donated livers outside the body can improve liver quality and transplant outcomes. You may qualify if you're an adult receiving a standard deceased-donor liver transplant that needs special preservation techniques.
Rotterdam, South HollandAges 18 years+ - NCT04993131Recruiting
Liver transplant for non-surgical bile duct cancer
This trial studies liver transplantation for people with a specific type of bile duct cancer near the liver that cannot be safely removed by surgery. It aims to improve outcomes by offering a transplant after the cancer responds to chemotherapy and spread has been ruled out on scans.
OsloAges 18 years+ - NCT04556214Recruiting
Liver transplant test for certain bile duct cancers
This trial studies whether a liver transplant can help people with a non-removable type of bile duct cancer in the liver. To be eligible, the cancer must be in the liver only (no spread), and you typically must already have had at least 6 months of treatment before being listed for transplant.
OsloAges 18 years+ - NCT06910722Recruiting
Liver transplant for bile duct cancer after treatment
This trial tests if a liver transplant can help people with a certain type of bile duct cancer (intrahepatic cholangiocarcinoma) that cannot be removed by surgery. Before the transplant, you would receive radiation therapy (SIRT) and chemotherapy to shrink the tumor.
Clichy-sous-BoisAges 18–65 - NCT04378023Recruiting
Liver transplant plus chemo-radiation for bile duct cancer
This study tests giving chemo and radiation before a liver transplant for an unresectable bile duct cancer near the liver (hCCA). If your cancer can’t be removed with surgery right now, this approach aims to shrink and control it so transplant may become an option.
Barcelona, BarcelonaAges 18–70 - NCT07775521Recruiting
Comparing two breathing tube methods for liver transplant surgery
This study compares two ways to help you breathe during liver transplant surgery: one uses a mask in your throat, the other uses a tube. The goal is to see which method works better and is safer for people like you.
Guangzhou, GuangdongAges 18–75 - NCT07634562RecruitingPhase 1/Phase 2
Reducing immune-suppressing drugs after liver transplant
This study tests a new way to lower the amount of immune-suppressing medicine needed after a liver transplant. It uses special treatments before or during the transplant to help your body accept the new liver with fewer drugs, which may reduce side effects.
Stanford, CaliforniaAges 18–55 - NCT06743464Recruiting
Rifaximin before liver transplant for better early liver function
This trial tests whether taking the antibiotic rifaximin just before and after a living-donor liver transplant can help prevent early problems with the new liver. It may be an option for adults having this surgery at the study hospital.
New Delhi, National Capital Territory of DelhiAges 18 years+ - NCT06875232Enrolling by invitation
Comparing CT and MRI scans for live liver donors
This study looks at how well CT scans and MRI scans (MRCP) show the blood vessels in the liver before a living donor liver donation. It aims to find out which scan is better at planning the surgery.
Rotterdam, South HollandAges 18–60 - NCT06455280RecruitingPhase 1
A study of Siplizumab for autoimmune liver disease patients awaiting transplant
This trial tests a drug called Siplizumab in people with autoimmune hepatitis or primary sclerosing cholangitis who are on the liver transplant waitlist. It aims to see if the drug can help manage their condition before and after transplant.
New York, New YorkAges 18 years+ - NCT07015723Enrolling by invitation
Liver fat study in living donors
This study looks at stored medical data from living liver donors to better understand fat in the liver (steatosis). It may help improve future transplant care.
Rotterdam, South HollandAges 18–60 - NCT02081755Enrolling by invitationPhase 4
Everolimus after liver transplant to lower liver cancer return
This trial studies whether everolimus, a transplant medicine, can safely reduce the chance that liver cancer comes back after liver transplant. It compares how well the treatment works while carefully monitoring side effects and safety.
San Francisco, CaliforniaAges 18 years+ - NCT05680246Recruiting
Study of long-term outcomes after special donor-liver preservation
This study looks at how well people do in the long run after liver transplant using donor livers that were preserved in a specific machine called DHOPE for more than 4 hours. It may help doctors understand whether this preservation method leads to better transplant outcomes over time.
GroningenAges 18 years+ - NCT06767579Recruiting
Comparing Delirium Risk After Liver Transplant: Inhaled vs. IV Anesthesia
This study compares how often confusion (delirium) happens after liver transplant when using two different anesthesia medicines: sevoflurane (inhaled gas) versus propofol (IV medicine). It helps doctors find out which anesthesia might be safer for your brain.
SeoulAges 19 years+ - NCT05477277Recruiting
MRI testing during liver transplant evaluation
This study looks at whether having an MRI scan during liver transplant planning helps predict who may have worse outcomes or higher risk of death. It focuses on adults with severe liver disease who are already being considered for a transplant.
Phoenix, ArizonaAges 18 years+ - NCT03228290Recruiting
Liver transplant care study using patient function check
This study looks at how people with liver disease function day to day, especially around liver transplant care. It may help improve how doctors assess readiness and recovery needs.
Little Rock, ArkansasAges 18 years+ - NCT07715500Recruiting
MRI of Bile Ducts in Living Liver Donors
This study uses an MRI scan to look at the bile ducts in healthy people who want to donate part of their liver. The goal is to see if the scan can help predict and prevent bile duct problems for the person receiving the liver.
New DelhiAges 18–55 - NCT07202910Recruiting
Validating liver imaging in children
This study tests if non-invasive imaging (like ultrasound) can replace liver biopsies in children with liver disease. It may help avoid the need for a needle biopsy in the future.
Gothenburg, Västra Götaland CountyAges Up to 25 years - NCT05276037Recruiting
PET/CT scan to guide liver transplant decisions in liver cancer
This trial studies how a whole-body PET/CT scan using a “tracer” called 18F-FDG can help decide which people with liver cancer (HCC) may benefit from a liver transplant. It may help the transplant team better sort out who is likely to do well after transplant.
AntwerpAges 18–80
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Common questions
- Are there clinical trials for liver transplantation?
- Yes. Clin2 currently lists 194 recruiting liver transplantation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liver transplantation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liver transplantation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.