Clinical trials
Male clinical trials
Below are recruiting male clinical trials, each written for real people, not researchers. We’re tracking 234 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07076771Recruiting
Testosterone and artery blockage in young men with heart disease
This study looks at whether testosterone levels are linked to how blocked the heart arteries are in young men (under 45) with early heart disease. It involves a one-time blood test during a planned cardiac catheterization.
SohagAges Up to 45 years - NCT06880302Recruiting
Male infertility research for sperm and tissue samples
This trial collects sperm, semen, and testicular tissue samples from men undergoing fertility treatments to build a biobank for research. If you are providing such samples for freezing, you can help advance understanding of male infertility.
Basking Ridge, New JerseyAges Any age - NCT06689085RecruitingPhase 3
Testosterone replacement study for adolescent boys with low testosterone
This trial tests a testosterone injection (XYOSTED) to see if it's safe and effective for replacing testosterone in teenage boys who have low levels due to a known medical condition. It lasts 52 weeks, with an optional 2-year follow-up.
Los Angeles, CaliforniaAges 12–17 - NCT06542237RecruitingPhase 1/Phase 2
Study of a new male birth control pill for healthy men
This trial tests an experimental birth control pill (YCT-529) taken daily. It aims to see if the drug can safely and effectively prevent pregnancy in healthy men who do not plan to have children in the future.
Grafton, AucklandAges 28–70 - NCT06339840Recruiting
Lifestyle change for weight and fertility in obese men
This study tests whether a lifestyle program (diet and exercise) can help men with obesity lose weight and improve their chances of fathering a child through fertility treatment. You and your partner can join if you are an obese male, your partner has a healthy weight and regular periods, and you are both planning treatment at our center.
Zhengzhou, HenanAges 22–40 - NCT06266416Recruiting
Black caregivers & girls empowerment study
This study tests a program called IMARA to support black male caregivers and the girls they care for. It aims to improve family relationships and reduce risky behaviors in girls.
Chicago, IllinoisAges 13 years+ - NCT06190899RecruitingPhase 1/Phase 2
Testing gedatolisib plus darolutamide in advanced prostate cancer
This trial tests a new combination of two drugs, gedatolisib and darolutamide, in men with prostate cancer that has spread and stopped responding to hormone therapy. The goal is to see if the combination can help control the cancer when standard treatments have stopped working.
Detroit, MichiganAges 18 years+ - NCT05501704RecruitingPhase 2
Testosterone-blocking therapy for male breast cancer
This Phase 2 study tests an oral treatment (called “ET”) to treat hormone-receptor–positive, HER2-negative invasive breast cancer in men. It may help shrink or control cancer without using standard cancer treatments first.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05370651Recruiting
Emsella chair versus sham treatment for male ejaculation problems
This trial compares an Emsella chair treatment to a sham (fake) treatment to help men with ejaculation difficulties. It wants to see whether the chair improves symptoms when other options have not helped enough.
Royal Oak, MichiganAges 18 years+ - NCT04049331RecruitingPhase 2
Testosterone therapy for cancer survivors with fatigue
This trial tests whether testosterone replacement can help male cancer survivors who have ongoing fatigue and low testosterone levels. It is for men who have completed chemotherapy or radiation and are cancer-free for at least a year.
Boston, MassachusettsAges 18–54 - NCT02395497RecruitingPhase 2/Phase 3
Penile transplant trial using immune-suppressing medicines
This study tests whether a donated penis can be successfully transplanted using medicines that calm the immune system to prevent rejection. It also looks at safety and recovery of function in men with severe penile loss from injury, cancer surgery, or birth conditions.
Baltimore, MarylandAges 18–69 - NCT07571928RecruitingPhase 1/Phase 2
New hormone treatment for men with no sperm
This study tests a new medication called leflutrozole for men with a condition where no sperm is produced (azoospermia). The drug may help increase hormone levels that support sperm production, potentially improving fertility.
HerlevAges 18–55 - NCT02568878RecruitingPhase 3
Creatine to help depression and anxiety in meth users
This trial studies whether creatine can reduce depression and anxiety symptoms in people who currently use methamphetamine and also have depression and anxiety. It may help by improving mood and anxiety scores over the course of the study.
Missoula, MontanaAges 18–59 - NCT01194648Recruiting
HIFU treatment for early prostate cancer
This trial studies a focused ultrasound treatment called HIFU for prostate cancer that appears limited to the early stages. It aims to treat cancer within the prostate while avoiding treatment spread to lymph nodes or distant organs.
London, EnglandAges Up to 90 years - NCT04760574Recruiting
HIV status and low testosterone in men
This study looks at whether low testosterone (often called male hypogonadism) is linked to having HIV. It compares HIV-positive men with HIV-negative men to better understand what contributes to hormone problems and how common they are.
TaipeiAges 20 years+ - NCT06175650Recruiting
Female-focused recovery plan after heart surgery
This study looks at how to improve recovery after heart surgery, especially for women. It reviews medical records from people who had heart surgery in the past or will have it in the next few years at two hospitals in Amsterdam.
Amsterdam, North HollandAges 18 years+ - NCT06193850Recruiting
Quality of life study for urology outpatients
This study is checking how your daily life is affected by your urology condition. It is an observational study, meaning you will just fill out questionnaires about your quality of life at your regular clinic visits.
Milan, LombardyAges 18 years+ - NCT06204731Recruiting
Exercise in low oxygen for young men
This study tests whether exercising in a low-oxygen environment (like high altitude) can affect stress, inflammation, and energy in your body. It is for young males who are generally healthy and can exercise safely.
KrakowAges 19–29 - NCT04064671Recruiting
Study of a specific erectile implant after sex reassignment surgery
This study looks at surgical outcomes after placing the Zephyr ZSI 475 FTM inflatable penile implant in people who had female-to-male (transmasculine) sex reassignment surgery. It may help improve how well this specific implant works and how patients do after surgery.
Ghent, Oost-VlaanderenAges 18–100 - NCT06239909Recruiting
Adjustable sphincter for urine leakage after prostate surgery
This trial is testing an adjustable artificial sphincter called Victo to help men who leak urine after prostate surgery. It may improve bladder control and quality of life.
Ostrava, Moravian-Silesian RegionAges 18 years+ - NCT07860346Recruiting
Measuring bone blood flow with a total-body PET/CT scan
This study tests a new way to measure blood flow in your bones using a special whole-body PET/CT scanner. It may help improve how doctors detect bone problems in the future.
LondonAges 50 years+ - NCT06289270Recruiting
Bladder cancer and urine bacteria study
This study looks at bacteria in urine and the bladder to understand if they play a role in causing bladder cancer. Researchers will compare samples from men with bladder cancer and healthy controls.
Cairo, Giza GovernorateAges 18 years+ - NCT03851627RecruitingPhase 4
Testosterone for fatty liver in overweight men with diabetes
This trial compares testosterone undecanoate versus a placebo (inactive pill) to see if it lowers fat in the liver measured by MRI. It focuses on overweight or obese men who have prediabetes or type 2 diabetes and low testosterone confirmed by blood tests.
ViennaAges 18–75 - NCT06115083Recruiting
Pelvic floor training for men with chronic pelvic pain
This trial tests if pelvic floor muscle training can reduce chronic pelvic pain in men. It also looks at how well patient-reported symptoms match physical exam findings.
StockholmAges 18 years+
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Common questions
- Are there clinical trials for male?
- Yes. Clin2 currently lists 234 recruiting male studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a male trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a male trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.