Clinical trials
Mastectomy clinical trials
Below are recruiting mastectomy clinical trials, each written for real people, not researchers. We’re tracking 124 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04345081Recruiting
Compare two breast surgery skin-sparing methods and recovery
This trial compares two types of mastectomy (with skin and nipple options) and implant reconstruction to see which gives better cosmetic results, comfort, and satisfaction. You may help doctors learn which approach leads to a better quality of life after surgery.
BudapestAges 18–65 - NCT06888388Recruiting
Safety of nipple-sparing mastectomy for women with high-risk genes
This study looks at the long-term safety of a type of breast surgery (nipple-sparing mastectomy) in women who carry certain inherited gene changes (BRCA1, BRCA2, PALB2, TP53, CDH1, or PTEN) that increase their risk of breast cancer. The goal is to understand how safe this surgery is over time for these women.
New Haven, ConnecticutAges 18–90 - NCT05490433Recruiting
Robot-assisted versus open nipple-sparing mastectomy with reconstruction
This trial compares two surgical approaches to remove the breast using a nipple-sparing mastectomy and do immediate breast reconstruction—either robot-assisted or open surgery. It aims to see how well each method works and how patients do afterward.
ChangwonAges 19–70 - NCT06415032Recruiting
Quilting sutures after mastectomy to improve recovery
This study tests whether using special stitches (quilting sutures) during mastectomy helps reduce fluid buildup or other complications after surgery. It is for people having one breast removed without immediate reconstruction.
LeuvenAges 18 years+ - NCT06817954Recruiting
Breast reconstruction after mastectomy for breast cancer
This trial tests how safe and effective it is to remove the breast (mastectomy) and rebuild it right away during the same surgery. It is for women with early-stage breast cancer who want reconstruction instead of breast-sparing surgery.
Nanjing, JiangsuAges 18–75 - NCT07230535Recruiting
Robotic vs standard mastectomy with DIEP reconstruction study
This trial compares how patients feel after open or robotic mastectomy combined with immediate DIEP flap reconstruction. It aims to see which approach improves wellbeing and recovery for women having this surgery.
BeaumontAges 18 years+ - NCT07548762Recruiting
Skin-Sparing vs. Standard Mastectomy for Breast Cancer
This study compares two surgical approaches to remove breast cancer: one that preserves more of the skin (skin-sparing) versus a standard approach. The goal is to see which method results in fewer wound-healing problems after surgery.
Guangzhou, GuangdongAges 18–75 - NCT07579117Recruiting
Video-Assisted Breast Surgery With Nipple Preservation
This trial tests a minimally invasive surgical technique that removes breast tissue while preserving the nipple and immediately reconstructing the breast. It may be suitable if you have early-stage breast cancer or are at high genetic risk and need preventive breast removal.
MilanAges 18 years+ - NCT07763080Recruiting
Shoulder exercise for pain after breast cancer treatment
This study tests if a specific shoulder exercise can reduce pain from a common side effect of breast cancer treatment. It may help women who have had a mastectomy and are taking aromatase inhibitors.
CairoAges 50–70 - NCT06823414Recruiting
Robotic-assisted nipple-sparing mastectomy trial
This trial tests a robotic-assisted surgery technique for women who need a mastectomy but can keep their skin and nipple. It aims to improve outcomes for breast cancer patients and those at high risk.
A Coruña, GaliciaAges 18 years+ - NCT07103109Recruiting
Exercise after mastectomy to help shoulder movement
This trial tests if special exercises to strengthen shoulder blade muscles can improve how your shoulder works after mastectomy. It may help if you have had trouble moving your shoulder for 3 to 4 months after surgery.
Giza, Giza GovernorateAges 35–55 - NCT07367568Recruiting
Nerve block comparison for mastectomy pain relief
This trial compares two types of nerve blocks to help manage pain during and after modified radical mastectomy. You may qualify if you are a woman between 18 and 65, have a healthy weight, and are scheduled for this surgery.
CairoAges 18–65 - NCT07234461Recruiting
Sexual well-being after mastectomy and reconstruction
This study looks at how mastectomy and breast reconstruction affect a woman's sexual well-being. If you are having a mastectomy for breast cancer or a preventive mastectomy because you are at high risk, you may be able to join.
Bari, ItalyAges 18 years+ - NCT07002983Recruiting
Shoulder exercises to help after mastectomy
This study is testing whether special exercises that retrain how you control your shoulder muscles can help reduce pain and improve movement after mastectomy. It is for women who had breast cancer surgery in the last few months and are now having shoulder problems.
GizaAges 40–55 - NCT06013514Recruiting
Study of Nagor Perle breast implants for reconstruction or cosmetic surgery
This study is following people who got Nagor Perle breast implants to see how they perform over time. It includes women getting implants for breast reconstruction, cosmetic augmentation, or revision surgery.
Manchester, United KingdomAges 18–65 - NCT05162677Recruiting
Study skin thickness and tissue after preventive breast removal
This study looks at what happens to the skin and remaining breast tissue after a preventive (non-cancer) mastectomy. It uses imaging and exams to understand why some patients may have skin healing problems.
UmeåAges 18–74 - NCT07608042Enrolling by invitation
Lung Boost breathing therapy for women after breast surgery
This study tests a breathing device and exercises designed to help women who've had breast removal surgery improve their lung function and breathing. It may help restore normal breathing patterns and quality of life after mastectomy.
Giza, Giza GovernorateAges 50–60 - NCT07647367Recruiting
Nerve blocks to reduce pain after breast cancer surgery
This trial compares two types of nerve-blocking injections given before breast removal surgery to help reduce pain and improve recovery. The goal is to see which method works better for comfort and quality of life after surgery.
Tanta, Gharbia GovernorateAges 18–65 - NCT07738770Recruiting
Comparing two numbing techniques for pain relief after mastectomy
This trial tests two different numbing injections to see which one works better for pain after breast cancer surgery. If you are having a mastectomy, you may be able to join and help find a better way to manage pain.
Jakarta, DKI JakartaAges 18–60 - NCT07718425Recruiting
Endoscopic mastectomy surgery study
This study tests a new, less invasive surgery called endoscopic mastectomy for women who need breast removal. It aims to see how well the surgery works, how the breast looks and feels afterward, and whether nipple sensation is preserved.
Ponderano, BIAges 18–75 - NCT02992574Recruiting
Radiation after mastectomy for certain node-negative breast cancers
This trial studies whether giving radiotherapy after a mastectomy helps prevent breast cancer coming back in women whose lymph nodes are not involved (or only very tiny spread). It may help reduce recurrence risk, especially for patients with higher-risk features despite node-negative early cancer.
Chandigarh, ChandigarhAges 18–80 - NCT04052893Recruiting
Surgery comparison for extensive breast duct cancer after mastectomy
This trial studies whether two different surgery approaches after modified radical mastectomy improve long-term disease control and quality of life for people with extensive breast duct cancer. It may help you understand which surgery plan could lead to better outcomes and recovery.
Benxi, LiaoningAges 45–75 - NCT04356235Recruiting
Comparing immediate vs delayed breast implant reconstruction results
This study compares two timing options for rebuilding the breast with implants, looking at cosmetic results, quality of life, and patient satisfaction. It may help you understand which approach could fit you better and what to expect over follow-up time.
BudapestAges 18–65 - NCT05146778Recruiting
Opioid-free anesthesia to reduce long-term post-mastectomy pain
This study tests whether a pain-control approach without opioids (strong pain medicines) can lower persistent pain after mastectomy. It may help people avoid long-term pain and opioid side effects.
SeoulAges 19–80
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Mastectomy trials by city
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Mastectomy trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for mastectomy?
- Yes. Clin2 currently lists 124 recruiting mastectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mastectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mastectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.