Clinical trials
Mastectomy clinical trials
Below are recruiting mastectomy clinical trials, each written for real people, not researchers. We’re tracking 118 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04345081Recruiting
Compare two breast surgery skin-sparing methods and recovery
This trial compares two types of mastectomy (with skin and nipple options) and implant reconstruction to see which gives better cosmetic results, comfort, and satisfaction. You may help doctors learn which approach leads to a better quality of life after surgery.
BudapestAges 18–65 - NCT06888388Recruiting
Safety of nipple-sparing mastectomy for women with high-risk genes
This study looks at the long-term safety of a type of breast surgery (nipple-sparing mastectomy) in women who carry certain inherited gene changes (BRCA1, BRCA2, PALB2, TP53, CDH1, or PTEN) that increase their risk of breast cancer. The goal is to understand how safe this surgery is over time for these women.
New Haven, ConnecticutAges 18–90 - NCT06415032Recruiting
Quilting sutures after mastectomy to improve recovery
This study tests whether using special stitches (quilting sutures) during mastectomy helps reduce fluid buildup or other complications after surgery. It is for people having one breast removed without immediate reconstruction.
LeuvenAges 18 years+ - NCT07579117Recruiting
Video-Assisted Breast Surgery With Nipple Preservation
This trial tests a minimally invasive surgical technique that removes breast tissue while preserving the nipple and immediately reconstructing the breast. It may be suitable if you have early-stage breast cancer or are at high genetic risk and need preventive breast removal.
MilanAges 18 years+ - NCT07548762Recruiting
Skin-Sparing vs. Standard Mastectomy for Breast Cancer
This study compares two surgical approaches to remove breast cancer: one that preserves more of the skin (skin-sparing) versus a standard approach. The goal is to see which method results in fewer wound-healing problems after surgery.
Guangzhou, GuangdongAges 18–75 - NCT07230535Recruiting
Robotic vs standard mastectomy with DIEP reconstruction study
This trial compares how patients feel after open or robotic mastectomy combined with immediate DIEP flap reconstruction. It aims to see which approach improves wellbeing and recovery for women having this surgery.
BeaumontAges 18 years+ - NCT06817954Recruiting
Breast reconstruction after mastectomy for breast cancer
This trial tests how safe and effective it is to remove the breast (mastectomy) and rebuild it right away during the same surgery. It is for women with early-stage breast cancer who want reconstruction instead of breast-sparing surgery.
Nanjing, JiangsuAges 18–75 - NCT05490433Recruiting
Robot-assisted versus open nipple-sparing mastectomy with reconstruction
This trial compares two surgical approaches to remove the breast using a nipple-sparing mastectomy and do immediate breast reconstruction—either robot-assisted or open surgery. It aims to see how well each method works and how patients do afterward.
ChangwonAges 19–70 - NCT04356235Recruiting
Comparing immediate vs delayed breast implant reconstruction results
This study compares two timing options for rebuilding the breast with implants, looking at cosmetic results, quality of life, and patient satisfaction. It may help you understand which approach could fit you better and what to expect over follow-up time.
BudapestAges 18–65 - NCT05162677Recruiting
Study skin thickness and tissue after preventive breast removal
This study looks at what happens to the skin and remaining breast tissue after a preventive (non-cancer) mastectomy. It uses imaging and exams to understand why some patients may have skin healing problems.
UmeåAges 18–74 - NCT06425874Recruiting
Study on how social factors affect well-being after breast surgery
This study looks at how things like income, education, and support systems affect the quality of life and emotional well-being of younger women (ages 18-50) after breast cancer surgery. The goal is to better understand and address these factors.
Guangzhou, GuangdongAges 18–50 - NCT07763080Recruiting
Shoulder exercise for pain after breast cancer treatment
This study tests if a specific shoulder exercise can reduce pain from a common side effect of breast cancer treatment. It may help women who have had a mastectomy and are taking aromatase inhibitors.
CairoAges 50–70 - NCT07738770Recruiting
Comparing two numbing techniques for pain relief after mastectomy
This trial tests two different numbing injections to see which one works better for pain after breast cancer surgery. If you are having a mastectomy, you may be able to join and help find a better way to manage pain.
Jakarta, DKI JakartaAges 18–60 - NCT07718425Recruiting
Endoscopic mastectomy surgery study
This study tests a new, less invasive surgery called endoscopic mastectomy for women who need breast removal. It aims to see how well the surgery works, how the breast looks and feels afterward, and whether nipple sensation is preserved.
Ponderano, BIAges 18–75 - NCT06676761Recruiting
Study of a new minimal scar mastectomy
This trial is testing a new surgical technique that leaves a smaller scar during mastectomy for breast cancer. It may be a good option if you want to keep the scar as small as possible.
SingaporeAges Any age - NCT07647367Recruiting
Nerve blocks to reduce pain after breast cancer surgery
This trial compares two types of nerve-blocking injections given before breast removal surgery to help reduce pain and improve recovery. The goal is to see which method works better for comfort and quality of life after surgery.
Tanta, Gharbia GovernorateAges 18–65 - NCT07653152Recruiting
Endoscopic vs open surgery for male breast reduction
This study compares two surgical approaches for removing male breast gland tissue in men with gynecomastia. One method uses small cuts and a camera (endoscopic), the other uses a standard cut (open surgery) – both aim to preserve the nipple and areola.
AntalyaAges 18–60 - NCT05440149RecruitingPhase 3
Radiation after surgery for certain node-positive breast cancer
This study tests whether giving radiation after breast surgery can improve outcomes for people with breast cancer that has spread to nearby lymph nodes (N1). You may be a candidate if you’ve already had surgery and meet specific details about your lymph nodes and cancer type.
Seoul, Jongro-guAges 19 years+ - NCT07608042Enrolling by invitation
Lung Boost breathing therapy for women after breast surgery
This study tests a breathing device and exercises designed to help women who've had breast removal surgery improve their lung function and breathing. It may help restore normal breathing patterns and quality of life after mastectomy.
Giza, Giza GovernorateAges 50–60 - NCT07561411Recruiting
Nerve blocks to reduce pain after breast removal surgery
This trial tests two types of nerve-blocking injections given during breast removal surgery to see which one better prevents long-term pain afterward. Both are given alongside general anesthesia and may help you recover with less chronic pain.
BeirutAges 18–80 - NCT07556952RecruitingPhase 4
Dexamethasone to reduce pain after breast removal surgery
This study tests whether dexamethasone (a common anti-inflammatory medication) can reduce pain after mastectomy (surgical removal of breast tissue). Researchers want to see if it helps patients recover with less pain and potentially fewer pain medications.
Montreal, QuebecAges 18–75 - NCT07507890Recruiting
Nipple-sparing mastectomy through one armpit incision
This trial tests a less invasive surgery for early-stage breast cancer that removes breast tissue through a single small cut in the armpit while keeping the nipple. It may be an option for women with small to medium breasts who are candidates for immediate breast reconstruction.
Candiolo, TurinAges 18 years+ - NCT07510698Recruiting
Same-day awake mastectomy with immediate breast reconstruction
This study tests whether people can have a mastectomy while awake (using numbing medicine instead of general anesthesia) and go home the same day with immediate breast reconstruction. It may be an option if you're healthy enough and have support at home.
Rome, RomeAges 18–75 - NCT07510269Recruiting
Nerve blocks for pain control during mastectomy
This study tests two different numbing shots for the chest wall to see which one provides better pain relief during and after mastectomy surgery.
Bursa, NilüferAges 18–75
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Mastectomy trials by city
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Mastectomy trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for mastectomy?
- Yes. Clin2 currently lists 118 recruiting mastectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mastectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mastectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.