Clinical trials
ME/CFS clinical trials
Below are recruiting me/cfs clinical trials, each written for real people, not researchers. We’re tracking 16 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07523113Recruiting
Brain Fog Treatment for ME/CFS Using Cognitive Training
This study tests whether a computerized cognitive training program combined with a mild electrical nerve stimulation device (worn on the ear) can help improve thinking and memory problems in people with ME/CFS. The goal is to see if this approach helps with brain fog and daily functioning.
Birmingham, AlabamaAges 18 years+ - NCT05778006Recruiting
Registry for people with ME/CFS
This study is a registry, meaning it collects information from people who have ME/CFS. It helps researchers better understand ME/CFS and may guide future studies that could improve care.
Munich, BavariaAges birth+ - NCT07529197Recruiting
Study of Immunoadsorption Treatment for Post-Infectious ME/CFS
This study observes how a blood-cleaning treatment called immunoadsorption works in patients with ME/CFS (severe fatigue condition) who have specific immune markers. Researchers will track whether this treatment helps reduce symptoms and improve daily functioning.
Berlin, State of BerlinAges 18–65 - NCT04151693Recruiting
Group therapy for chronic fatigue syndrome
This trial tests a health-psychology–based rehabilitation program delivered in a group setting for people with chronic fatigue syndrome (ME/CFS). It may help by teaching strategies to cope with symptoms and improving daily functioning through structured group support.
LahtiAges 18–65 - NCT06005246Recruiting
Munich ME/CFS Study for Young People
This study is tracking children, teens, and young adults (up to age 25) who developed ME/CFS after an infection. It aims to better understand the condition in younger people.
Munich, BavariaAges Up to 25 years - NCT06211062RecruitingPhase 2
Probiotics for chronic fatigue syndrome with IBS
This study tests whether a specific mix of probiotics can help people with chronic fatigue syndrome (ME/CFS) who also have irritable bowel syndrome (IBS). It's a small trial to see if improving gut health can ease symptoms.
Fort Lauderdale, FloridaAges 45–70 - NCT06952413RecruitingPhase 2
Rituximab for chronic fatigue syndrome (ME/CFS) trial
This trial tests if rituximab, a drug that affects the immune system, can help people with ME/CFS. You'll receive the drug in the hospital and be monitored for safety and improvement.
Kodaira, TokyoAges 18–65 - NCT07352254Recruiting
At-home medical care for housebound ME/CFS patients
This study is testing a way to improve medical care for people with ME/CFS (including post-COVID ME/CFS) who are mostly homebound. The goal is to see if bringing healthcare to your home helps you better manage your condition.
HanoverAges 18–69 - NCT07256795Enrolling by invitation
ME/CFS after COVID-19 vs. before the pandemic
This study looks at how the brain's protective barrier and immune system work in people with ME/CFS, comparing those who got sick before the COVID-19 pandemic to those who developed ME/CFS after a COVID-19 infection. It aims to understand why some people have lasting brain fog, fatigue, and other neuropsychiatric symptoms.
Baltimore, MarylandAges 18–70 - NCT07715838Recruiting
PEM as a starting point to study ME/CFS
This study looks at how post-exertional malaise (PEM) affects people with ME/CFS. It aims to understand the condition better and find new ways to help.
GroningenAges 18–65 - NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+ - NCT06366724RecruitingPhase 2
Life Improvement Trial for ME/CFS
This trial tests a new treatment for ME/CFS (chronic fatigue syndrome) that includes symptoms like dizziness when standing. It uses a smartphone app to track your progress and aims to see if the treatment can improve your daily life.
Boston, MassachusettsAges 18–70 - NCT07009691Recruiting
Hydrogen water for ME/CFS patients
This trial tests whether drinking hydrogen-rich water can improve heart rate variability (a measure of nervous system function) in people with ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome). The goal is to see if this simple intervention helps reduce symptoms.
Stony Brook, New YorkAges 18–65 - NCT07227441Recruiting
Chronic Infections and Inflammation in ME/CFS
This study looks at how chronic infections and inflammation affect people with ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) compared to healthy people. Researchers want to understand what causes symptoms and find better ways to help.
San Francisco, CaliforniaAges 18 years+ - NCT07551999Recruiting
Voice Analysis Tool for ME/CFS Diagnosis and Monitoring
This study tests a smartphone app that analyzes your voice to help diagnose and track myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)—a condition causing extreme tiredness and other symptoms. Researchers want to see if voice patterns can be a simple, at-home way to monitor your condition over time.
Rochester, MinnesotaAges 18 years+ - NCT06257420Enrolling by invitation
Low-dose rapamycin for ME/CFS and Long-COVID
This trial tests whether a low dose of rapamycin, a drug that may help regulate the immune system, can improve symptoms in people with ME/CFS or Long-COVID.
Palo Alto, CaliforniaAges 18–65
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Common questions
- Are there clinical trials for me/cfs?
- Yes. Clin2 currently lists 16 recruiting me/cfs studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a me/cfs trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a me/cfs trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.