Clinical trials
Menopause clinical trials
Below are recruiting menopause clinical trials, each written for real people, not researchers. We’re tracking 156 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06365905Recruiting
AI ultrasound test for endometrial cancer after menopause
This study uses an artificial intelligence (AI) tool to analyze ultrasound images of the uterus to see if it can find early signs of endometrial cancer or a condition called atypical hyperplasia (which can lead to cancer). It may help women with postmenopausal bleeding avoid more invasive biopsies.
Scottsdale, ArizonaAges 55 years+ - NCT06364267RecruitingPhase 2
Low dose exemestane vs low dose tamoxifen for breast cancer prevention
This trial compares two low-dose medications, exemestane and tamoxifen, to see which is better at preventing breast cancer in postmenopausal women who have a higher risk. You would take one of these pills daily for a few years, and the study will check how well it works and what side effects occur.
Genova, ItalyAges Any age - NCT06347926Recruiting
Light therapy for menopause symptoms in breast cancer
This study tests a light-based treatment (photobiomodulation) to see if it improves sexual quality of life for women with breast cancer who have menopause-related vaginal symptoms that the usual moisturizers did not relieve.
Montpellier, HéraultAges 18 years+ - NCT06238700Recruiting
Studying allopregnanolone for depression in midlife women
This trial tests whether allopregnanolone, a natural brain chemical, can help depression in women going through menopause. It compares the effects against a placebo to see if it improves mood symptoms.
Boston, MassachusettsAges 40–60 - NCT05831709Recruiting
Hormone therapy and supervised exercise in menopausal women
This study looks at how hormone replacement therapy and a supervised exercise program may change body composition, heart health risk, and insulin sensitivity in postmenopausal women. It may help participants understand which combination works best for metabolic and cardiovascular health after menopause.
GhentAges 45–65 - NCT05953090Recruiting
Vaginal irritation study with device use and long follow-up
This trial studies a treatment for long-lasting vaginal/vulvar irritation caused by conditions like vaginal atrophy or certain skin conditions of the vulva. You would try the study product/device and be followed over time to see how symptoms recover.
Birmingham, AlabamaAges 18 years+ - NCT05590949Recruiting
Bone health study for breast cancer survivors off bone medication
This study looks at bone complications in women who have finished treatment with denosumab (a bone-strengthening drug) and aromatase inhibitors (hormone therapy for breast cancer). It aims to learn more about what happens to bones after stopping these medications, which may help guide future care.
Basking Ridge, New JerseyAges 18 years+ - NCT05440617Recruiting
Biobank for people having testicle-protecting cancer treatment
This study collects and stores biological samples from people who are planning to undergo OTC, a treatment used to help protect fertility during cancer therapy that can harm reproductive cells. It may help future research by providing researchers with tissue/blood samples linked to this treatment.
Bethesda, MarylandAges 4–35 - NCT05401630Recruiting
Mental stress testing in postmenopausal women with chest pain
This study looks at how your heart reacts to mental stress in postmenopausal women, including those with chest pain and those with or without blocked heart arteries. It uses a special heart scan (MIBG) and stress tasks to understand differences that may help guide future care.
Atlanta, GeorgiaAges 45 years+ - NCT05251324Recruiting
Study effects of hot flushes on heart and blood pressure
This study looks at how hot flushes (also called hot flashes) may affect heart function and blood pressure in postmenopausal people. You may be able to take part if you are not currently using hormone therapy or can stop it for the study.
Minneapolis, MinnesotaAges 40–70 - NCT05193968Recruiting
Study hot flashes and blood vessel function in women
This study looks at how hot flashes relate to how well your blood vessels work in the body. It may help researchers understand the body changes behind hot flashes, which could guide future treatments.
Rochester, MinnesotaAges 40–60 - NCT04458532Recruiting
Exercise program to boost heart health after early breast cancer
This trial studies whether a structured exercise program can improve cardiovascular (heart and blood vessel) health in post-menopausal women after early-stage breast cancer treatment. It specifically targets women who have trouble with exercise and have completed cancer treatment within the last 1 to 5 years.
Hartford, ConnecticutAges 21–80
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Common questions
- Are there clinical trials for menopause?
- Yes. Clin2 currently lists 156 recruiting menopause studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a menopause trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a menopause trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.