Clinical trials
Mental Health (Depression) clinical trials
Below are recruiting mental health (depression) clinical trials, each written for real people, not researchers. We’re tracking 310 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06544941Recruiting
Improving sleep and mental health in new moms
This study compares two types of bassinets to see if one helps mothers sleep better and feel less stressed after childbirth. It is for pregnant women with a military connection who are willing to use a bassinet and give a blood sample.
Colorado Springs, ColoradoAges 18–45 - NCT03987633Recruiting
Study links health records and samples to understand health gaps
This study asks people affected by a specific illness (or their family member) to share saliva (and sometimes blood) and answer health and quality-of-life questions. The goal is to better understand and reduce health inequality by matching new information with medical records.
Wolverhampton, West MidlandsAges 6 years+ - NCT07305701Recruiting
Study on Medical Students' Mental Health
This study follows first-year health students at the University of Orléans to understand their mental health over time. It aims to find ways to support students' well-being during their studies.
Orléans, LoiretAges 18 years+ - NCT07217561Recruiting
Doula support program to improve mental health before and after birth
This trial tests whether extra training and resources for doulas can help pregnant people and new parents feel better emotionally. Doulas who join will learn new ways to support clients, and participants will get care from a trained doula.
Boston, MassachusettsAges Any age - NCT07129070Recruiting
Just-in-Time Training for Youth Mentors
This trial tests a new training program for mentors working with middle and high school students. It aims to help mentors better support youth who may be experiencing depression.
Minneapolis, MinnesotaAges 12 years+ - NCT07073963Recruiting
Online groups for sarcoidosis fatigue
This trial tests whether virtual group sessions can help reduce fatigue related to sarcoidosis. You'll join a supportive online group with others who have similar symptoms.
Cleveland, OhioAges 18 years+ - NCT06430853Enrolling by invitation
Pregnancy support study for moms with anxiety or depression
This study tests if a mental health program during pregnancy can help mothers with past or current anxiety or depression. You'll get support and you may feel better and have a healthier pregnancy.
Stanford, CaliforniaAges 18 years+ - NCT06178328Recruiting
Online mental health program for Canadian adults
This study is testing a short online mental health program for adults in Canada who are seeking help. It aims to see if the program helps people feel better.
Regina, SaskatchewanAges 18 years+ - NCT06897553Recruiting
ACT for Better Mental Health with Neurologic Illness
This study tests a type of talk therapy (ACT) to help people with neurological conditions like Parkinson’s, MS, or epilepsy feel better emotionally. It's for those who are struggling with depression, anxiety, or stress and are ready to work on their mental health.
BielefeldAges 18 years+ - NCT04159662Recruiting
Brain scans to study thinking in schizophrenia and depression
This study uses brain imaging to better understand how thinking works in people with schizophrenia or major depression. Your results may help researchers learn what brain patterns match different thinking and symptoms.
Ottawa, OntarioAges 18–60 - NCT07212075Recruiting
Digital twin study for mental health in diabetes
This study uses digital twins—a virtual model of your health—to track how your mental health changes with diabetes. It aims to find patterns that could help personalize mental health care.
Bad Mergentheim, Baden-WurttembergAges 18–80 - NCT06804954Recruiting
Online CBT vs. usual care for mild mental health issues
This study tests an online CBT program (cognitive behavioral therapy you do from home) versus usual care for people with mild to moderate anxiety, depression, or stress. It aims to help you manage symptoms before they become more serious.
Gustavsberg, Stockholm CountyAges 18 years+ - NCT06770075Recruiting
Brightline: testing a wellness app for college students
This study tests a smartphone app that may help students track and improve their mental well-being. Over 6 months, you will wear a device that monitors things like activity and sleep, and use a simple app to check in on your mood. It's designed for full-time undergraduates who do not have a current mental health condition and are not receiving mental health treatment.
SingaporeAges 18–25 - NCT07225088Recruiting
Mental health support for Latino cancer patients
This study tests a mental health intervention called DESCANSO to help Latino people with cancer who feel depressed, have trouble sleeping, or are very tired. You may join if you are a Latino adult with stage I-III solid tumor cancer, speak Spanish, and are currently or recently finished treatment.
Basking Ridge, New JerseyAges 21–100 - NCT07223346Recruiting
Fitness and therapy for Latina cancer survivors
This trial offers a program combining exercise and mental health support for Latina women in Colorado who have recently finished cancer treatment or are still undergoing it. It aims to improve well-being through group sessions focused on physical activity and coping skills.
Fort Collins, ColoradoAges 18 years+ - NCT07014852RecruitingEarly Phase 1
Inuit mental health trial with cultural foods and activities
This trial tests whether a program that includes traditional country foods, group conversations, and cultural workshops can improve mental health for Inuit adults. It is designed with Inuit knowledge to make the study feel supportive and relevant.
Arviat, NunavutAges 18–65 - NCT06988410Recruiting
Income changes and mental health study
This study looks at how ups and downs in income affect mental health. If you're a woman between 18 and 60 living with up to 4 other adults, you may be able to join.
TamaleAges 18–60 - NCT06768749Recruiting
Melatonin lotion for better sleep and mood
This trial tests whether using a scented melatonin lotion before bed can improve sleep and reduce anxiety or depression symptoms. It may be a good fit if you have mild sleep problems and some mood symptoms but are not currently taking medication for them.
Redlands, CaliforniaAges 18–21 - NCT06389565Recruiting
Change My Story: A mental health program for young adults with HIV
This study tests a mental health program to help young people living with HIV who feel down or depressed. It's designed to see if talking through your story can help you feel better and function day-to-day.
Ibadan, Oyo StateAges 16–29 - NCT05603000Recruiting
Emotion-focused therapy for parents of anxious or struggling children
This study tests an emotion-focused family therapy program for parents of children (ages 7–15) who are dealing with anxiety, depression, or behavior challenges. It may help families improve how emotions are understood and managed through parent participation and home life support.
Guelph, OntarioAges 7–15 - NCT04356274Enrolling by invitation
Improving access to addiction and mental health care at VA clinics
This study tests an approach to help VA clinics reach more Veterans with proven treatments for addiction and mental health conditions. It focuses on clinic-level processes (not individual medications) to increase how widely evidence-based care is delivered.
Palo Alto, CaliforniaAges 18 years+ - NCT03906435Recruiting
Cognitive therapy to prevent problems for very premature NICU babies
This study offers a counseling approach to help prevent “Vulnerable Child Syndrome” in babies born very early and cared for in the NICU. It focuses on support during the early months after birth and compares outcomes for families getting the therapy versus usual support.
Dallas, TexasAges Any age - NCT07679204Recruiting
Personality and life satisfaction in bipolar and depression
This study looks at how personality traits and life satisfaction affect people with bipolar II disorder or major depression. You will fill out questionnaires about your feelings and daily life.
ElâzığAges 18 years+ - NCT06105970Recruiting
Chinese mental health study for adults
This study looks at how different mental health symptoms relate to each other in Chinese adults. Researchers want to understand patterns of psychological distress, which could help improve future treatments.
ShanghaiAges 18 years+
Hear when a new Mental Health (Depression) trial opens
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Common questions
- Are there clinical trials for mental health (depression)?
- Yes. Clin2 currently lists 310 recruiting mental health (depression) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health (depression) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health (depression) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.