Clinical trials
Mental Health (Depression) clinical trials
Below are recruiting mental health (depression) clinical trials, each written for real people, not researchers. We’re tracking 316 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06071221Recruiting
Mental health program for home health aides
This study tests a program to help home health aides feel better mentally. If you are a home health aide who speaks English or Spanish, has mild depression, high stress, or loneliness, and has at least 1 year of experience, you may be able to join.
New York, New YorkAges 18 years+ - NCT07606248Recruiting
Virtual forest mindfulness for pregnant women's mental health
This study tests whether using virtual reality to explore a calming digital forest helps reduce stress and improve mood during pregnancy. You'd use a VR headset a few times to practice mindfulness (focused breathing and relaxation) and complete short surveys about how you're feeling.
HsinchuAges 18 years+ - NCT05763537Recruiting
Study exploring how doulas support pregnancy mood changes
This study looks at how having a doula affects support and wellbeing for people experiencing pregnancy-related mood and anxiety changes. It may help you and others learn what kind of doula support is most helpful during pregnancy.
Missoula, MontanaAges 18 years+ - NCT06257095Recruiting
Phone Support Program for Older Adults Leaving APS
This study is testing a phone-based support program for older adults who have been helped by Adult Protective Services and are now moving on. College students in health fields will provide friendly, weekly check-in calls to help with social and emotional needs.
Houston, TexasAges 65 years+ - NCT07195721Recruiting
How special contact lenses affect mental health
This study looks at whether PROSE or scleral lenses can improve mental health in people with certain eye surface conditions. It may be a good fit if you have a dry eye or related disease and are considering these lenses.
Needham, MassachusettsAges Any age - NCT06936202Recruiting
Spirulina pill study for healthy adults
This study tests whether a supplement called spirulina (a type of algae) can improve mental health in healthy adults. You would take spirulina daily and have your mood and well-being checked over several weeks.
Phoenix, ArizonaAges 16–65 - NCT06788028Recruiting
Mental health support for children in Azerbaijan
This trial tests a program to help children ages 7 to 14 who may be at risk for emotional or behavioral problems. It aims to see if providing support to both the child and their parent can improve their mental health.
Baku, AzerbaijanAges 7–14 - NCT06919133Enrolling by invitation
Using smartphone markers to manage depression symptoms
This study tests whether using a smartphone app to track your mood and behavior can help you manage depression symptoms better. You'll use digital tools to monitor your own progress and learn self-management strategies.
FrederiksbergAges 18 years+ - NCT06623682Recruiting
Online mental health support for university students
This trial tests a self-help program with support services for students in Hong Kong who are experiencing moderate to severe anxiety or depression. It aims to see if these tools can improve mental health.
Hong KongAges 18 years+ - NCT05825040Recruiting
Testing an online mental health program for anxiety and depression
This trial tests an “online” mental health approach to help people with moderate to severe anxiety and/or depression. If you qualify, you may be invited to use the program and share feedback as part of a study.
Shatin, N.T.Ages 17 years+ - NCT06087159Recruiting
Mental health toolkit for teachers and caregivers in Uganda
This trial tests if a personalized mobile health toolkit can help teachers and caregivers in Uganda manage stress and support mental health. If you are a teacher or a parent in the study schools, this program may provide tools to improve your wellbeing.
KampalaAges 18 years+ - NCT05768841Recruiting
Study mental health in runners, triathletes, and endurance athletes
This study looks at how common mental health concerns are among endurance athletes like marathon runners, ultramarathon runners, and triathletes. It may help researchers better understand which athletes may need support.
Pierre-BéniteAges 16 years+ - NCT05824234Recruiting
REFOCUS program for mental health care teams
This trial tests whether a training program for mental health teams improves care for people with certain mental health conditions. You may be included if your clinic/team is using the REFOCUS training and you meet the study language and consent requirements.
Lyon, RhôneAges 15–65 - NCT05833555Recruiting
Harlem Strong mental health support for adults
This program is for Black and Latino adults in Harlem who are dealing with mild to moderate depression symptoms. It aims to identify people who may benefit from mental health support and connect them with the right level of care.
New York, New YorkAges 18–65 - NCT06046989Recruiting
Building emotional awareness and mental health in parenting
This study tests a program to help parents with high levels of depression, anxiety, or anger learn skills to manage their emotions and support their child's mental health. It includes brain scans to see how the program might work.
Calgary, AlbertaAges 18–65 - NCT06049433Recruiting
Mental health support for new and expecting mothers
This study tests a program to help pregnant women and new mothers who may be at risk for depression after childbirth. The program offers extra support and resources to improve your mental health and well-being.
Salt Lake City, UtahAges 18 years+ - NCT06306092Recruiting
Sleep for better mental health and school grades
This study looks at how helping teenagers sleep better can improve their mental health and school grades. It is open to students in Swedish high schools and upper secondary schools.
Kristianstad, Skåne CountyAges 13–19 - NCT06440798Recruiting
Social Media and Mental Health Study
This study looks at how mental health content on social media affects your well-being. If you use social media and live in Singapore, you may be able to take part.
SingaporeAges 18–34 - NCT06442774Recruiting
Mamaconecta: app support for moms' mental health
This study tests a digital tool called MamaConecta to support mothers' mental health during pregnancy. If you are between 12 and 14 weeks pregnant, speak Spanish, and have a smartphone, you may be able to join.
Barcelona, CataloniaAges 18 years+ - NCT06456307Recruiting
Stepped care for mood and anxiety during pregnancy
This study tests a step-by-step approach to help pregnant women who are feeling anxious or down. If you are at least 28 weeks pregnant and feeling stressed, worried, or sad, the study will offer you support and check on how you are doing.
NairobiAges 14 years+ - NCT06502717Recruiting
Personalized nutrition program for mood and mental health
This trial tests a personalized nutrition program designed to improve mood and mental health. You'll use a smartphone app and receive meal plans based on your unique needs. It's for adults with mild to moderate depression who are ready to change their diet.
Bothell, WashingtonAges 25–75 - NCT06582784Recruiting
Using a phone app to help cancer survivors with depression
This study tests a mobile app to help cancer survivors who are feeling depressed. If you have a smartphone and are willing to use an app for mood support, you may be able to join.
Charleston, South CarolinaAges 18 years+ - NCT06651801Recruiting
Group therapy for anxiety or depression
This trial tests whether a virtual group therapy program is a good way to help people in Manitoba with anxiety or depression. If you're looking for support and can join a small online group, this might be a helpful option.
Winnipeg, ManitobaAges 18 years+ - NCT06722781Recruiting
Online group therapy for common mental health conditions
This trial tests an online group therapy for people waiting for high intensity CBT. It aims to provide quicker support for conditions like depression, anxiety, and PTSD.
Doncaster, South YorkshireAges 17 years+
Hear when a new Mental Health (Depression) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for mental health (depression)?
- Yes. Clin2 currently lists 316 recruiting mental health (depression) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health (depression) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health (depression) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.