Clinical trials
Mental Health (Depression) clinical trials
Below are recruiting mental health (depression) clinical trials, each written for real people, not researchers. We’re tracking 315 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05696704Recruiting
Telehealth program to support mental health in family caregivers
This study tests a video/phone-based program to help reduce anxiety and depression symptoms in people caring for a family member or friend with dementia. It may help caregivers feel better and cope more effectively while caring for someone they love.
Lubbock, TexasAges 18–120 - NCT07413887Recruiting
Family program for obsessive thoughts and behaviors in youth
This trial tests a family-based program for children and teens with mild to moderate obsessive thoughts or compulsive behaviors. It aims to help reduce distress and improve daily functioning at home and school.
FrederiksbergAges 3–17 - NCT06623799Recruiting
Allergic rhinitis, help-seeking, and mental health study
This study looks at how people with allergic rhinitis (hay fever) seek help and how that relates to their mental health. Researchers hope to learn more about the connection between allergies, anxiety, and depression over time.
West Palm Beach, FloridaAges 4–100 - NCT07631845Recruiting
Music and breathing exercises to improve mood and resilience in older adults
This study tests whether combining music with breathing exercises can help older adults manage anxiety and depression. You'll learn techniques that may improve your emotional well-being and resilience.
Hong KongAges 65 years+ - NCT07667738RecruitingPhase 2
Parent support program in Peru for parents of young children
This study tests a therapy program called CETA for parents in a specific area of Lima, Peru. It aims to help parents improve their mental health, which may also benefit their children ages 4 to 6.
LimaAges 18 years+ - NCT07475039Recruiting
Friendly phone calls to support older adults
This study tests whether a program of friendly phone calls from trained volunteers can help older adults feel more connected and supported. If you are 65 or older and already receive home-delivered meals or other services, you may be able to join.
Gainesville, FloridaAges 55 years+ - NCT05862636Recruiting
Testing who benefits most from mindfulness meditation
This study looks at people who take part in a mindfulness program at specific study locations and examines who does best. You might be eligible if you are already joining the mindfulness intervention and can complete study tasks in the required language.
AntwerpAges 18 years+ - NCT07223736Recruiting
AI education for new mothers after birth
This study tests an AI-based education tool for first-time mothers to help with recovery and reduce loneliness after childbirth. You participate from home using your smartphone for 2-6 weeks after delivery.
La Jolla, CaliforniaAges 18 years+ - NCT05322343Recruiting
Study biobank and brain health in people age 55–80
This study collects blood samples to build a biobank and learn how brain health changes with age. Some participants may also do an MRI scan to better understand brain changes and immune response.
Bordeaux, BordeauxAges 55–80 - NCT06246214Recruiting
Biological rhythms for perinatal mental health
This study looks at whether understanding your body's daily rhythms (like sleep and activity) can help treat depression after childbirth. If you are 4-6 weeks postpartum and have been diagnosed with postnatal depression, this could be an option for you.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06438276Recruiting
Mental health support for teens through school services
This study tests whether psychiatric outreach nurses can help teenagers aged 12-16 who are dealing with mood issues, anxiety, obsessive-compulsive or eating disorder symptoms, or mild self-harm. The goal is to see if this extra support improves their mental health compared to the usual school services.
Kuopio, Northern SavoniaAges 12–16 - NCT06604104Recruiting
Visual Frailty Study in Older Adults with AMD
This study looks at something called 'visual frailty' in older adults with advanced age-related macular degeneration (AMD). It aims to develop a tool to better understand how vision loss affects daily life and overall health in people aged 60 and over.
Edinburgh, ScotlandAges 60 years+ - NCT06923423Recruiting
Cognitive processing therapy for drug use and trauma in prison
This study tests if a type of therapy called cognitive processing therapy (CPT) can help people in prison who have both a drug use problem and trauma-related stress. If you qualify, you would receive CPT and be compared to those getting usual care.
Little Rock, ArkansasAges 18 years+ - NCT07024979Recruiting
Music therapy for university students' mental health
This trial tests whether a music therapy program can help university students with moderate stress, social problems, or trouble adjusting to college life. It aims to improve your mental health and well-being.
Hong KongAges 18–35 - NCT06823492Recruiting
Early life and brain study
This study looks at how your early life experiences may affect your brain and behavior. You would visit the University of Manchester for assessments and help researchers understand these connections.
ManchesterAges 18–25 - NCT05509166Recruiting
Therapy for sexual-minority women dealing with anxiety or depression and drinking
This trial tests a type of supportive psychotherapy to help sexual-minority women improve mental well-being and reduce drinking. It may help if you’re experiencing depression or anxiety and have been drinking heavily, and you’re not already in certain kinds of treatment.
New York, New YorkAges 18 years+ - NCT06462196Recruiting
Study of Depression, Bipolar Disorder & Suicide Risk
This study looks at how depression, bipolar disorder, and suicide risk naturally change over time. It aims to better understand these conditions so doctors can improve treatments.
Bethesda, MarylandAges 18–120 - NCT06568419Recruiting
Online therapy for mental health and work
This trial tests an online program to help people on sick leave due to anxiety or depression return to work. You would receive therapy through a secure website while staying with your regular mental health care team.
Oslo, BærumAges 18–65 - NCT06790641Recruiting
Supporting mental health during and after pregnancy
This study aims to improve mental health care for people during and after pregnancy. It involves interviews or focus groups with healthcare providers, peer mentors, and patients to understand how to make support services more helpful and accessible.
Shrewsbury, MassachusettsAges 18–70 - NCT07609550Recruiting
Early mental health support for pregnant and new mothers
This study tests whether connecting pregnant women and new mothers who have depression or anxiety to mental health care earlier helps them. You'll be part of a larger research program and may receive support through a smartphone app.
Mairena del Aljarafe, SevillaAges 18 years+ - NCT07217561Recruiting
Doula support program to improve mental health before and after birth
This trial tests whether extra training and resources for doulas can help pregnant people and new parents feel better emotionally. Doulas who join will learn new ways to support clients, and participants will get care from a trained doula.
Boston, MassachusettsAges Any age - NCT03987633Recruiting
Study links health records and samples to understand health gaps
This study asks people affected by a specific illness (or their family member) to share saliva (and sometimes blood) and answer health and quality-of-life questions. The goal is to better understand and reduce health inequality by matching new information with medical records.
Wolverhampton, West MidlandsAges 6 years+ - NCT06178328Recruiting
Online mental health program for Canadian adults
This study is testing a short online mental health program for adults in Canada who are seeking help. It aims to see if the program helps people feel better.
Regina, SaskatchewanAges 18 years+ - NCT06544941Recruiting
Improving sleep and mental health in new moms
This study compares two types of bassinets to see if one helps mothers sleep better and feel less stressed after childbirth. It is for pregnant women with a military connection who are willing to use a bassinet and give a blood sample.
Colorado Springs, ColoradoAges 18–45
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Common questions
- Are there clinical trials for mental health (depression)?
- Yes. Clin2 currently lists 315 recruiting mental health (depression) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mental health (depression) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mental health (depression) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.