Clinical trials
Metabolic Disorders clinical trials
Below are recruiting metabolic disorders clinical trials, each written for real people, not researchers. We’re tracking 133 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT01962415RecruitingPhase 2
Reduced-intensity stem cell transplant for non-cancer disorders
This trial tests whether a gentler (reduced-intensity) conditioning treatment before a stem cell transplant works for non-cancer diseases. It uses specific donor stem cell matches and checks heart, lung, liver, and kidney function to help lower transplant stress while still aiming for benefit.
Pittsburgh, PennsylvaniaAges 2 months–55 years - NCT06336070Recruiting
Power training for metabolic health in postmenopausal cancer survivors
This trial compares two types of exercise—muscle power training and metabolic power training—to see which better improves your body's ability to use energy and control heart function. You may qualify if you are a postmenopausal woman who has had breast cancer and is not currently active.
Valencia, ValenciaAges 35–75 - NCT04528355Recruiting
Study of hospital data after stem cell transplant for non-cancer illness
This study collects medical information from people with certain non-cancer conditions who receive a stem cell transplant. It may help doctors better understand transplant outcomes and care, since the study focuses on data collection rather than adding new treatment.
Pittsburgh, PennsylvaniaAges 2 months–60 years - NCT05866107Recruiting
App and smart scale program for weight loss in bipolar or schizophrenia
This study tests whether using a health app and smart body-fat scales helps people who are overweight or obese lose weight. It is designed for adults with bipolar disorder or schizophrenia who are stable and can safely follow the weight-loss and activity plan.
Beijing, Beijing MunicipalityAges 18–60 - NCT06925997RecruitingEarly Phase 1
Bile acids after gastric bypass: metabolic effects study
This trial looks at how bile acids affect metabolism in people who have had gastric bypass surgery. It compares three groups: those who had diabetes before surgery, those without diabetes, and those with type 2 diabetes.
HvidovreAges 18 years+ - NCT06092346Recruiting
Understanding rare purine and pyrimidine metabolism disorders
This study aims to learn more about rare disorders of purine and pyrimidine metabolism (DPPM), which can affect the brain, immune system, kidneys, and muscles. Researchers will study people with these disorders, their family members, and healthy volunteers to better understand the condition over time.
Bethesda, MarylandAges 1 month–100 years - NCT03540758RecruitingPhase 2
Study of how brain sugar control channels affect blood sugar
This Phase 2 study tests how certain channels in the brain help control how your body makes and releases sugar (glucose). It may help explain blood sugar problems in people with type 2 diabetes and healthy volunteers.
The Bronx, New YorkAges 21–70 - NCT03742011Recruiting
Study of babies born to mothers with PCOS in Guangzhou
This study looks at children born to mothers who have polycystic ovary syndrome (PCOS). It aims to learn about their health by following families in Guangzhou over time.
Guangzhou, GuangdongAges Up to 18 years - NCT04201600Recruiting
Study how blood sugar swings affect thinking in prediabetes
This study looks at how “blood sugar variability” (how much glucose levels bounce around) may affect thinking and memory in people with prediabetes. You may be eligible if you’re older and don’t already have diabetes or conditions that can strongly affect the brain or blood vessels.
Baltimore, MarylandAges 50 years+ - NCT04654000Recruiting
Rheopheresis to treat painful skin damage in calciphylaxis
This trial studies whether a treatment called rheopheresis, added to standard care, can help people with calciphylaxis whose skin wounds are getting worse. It may be considered when ulcers or dead (necrotic) skin appear despite conventional treatment.
AngersAges 18 years+ - NCT04802707RecruitingPhase 2
Study drug for mitochondrial depletion disorder due to gene changes
This Phase 2 trial tests a treatment made from deoxynucleosides to help people with mitochondrial depletion disorder caused by certain gene changes. If you match the genetic diagnosis, the study may see whether the treatment improves symptoms or disease markers.
Montreal, QuebecAges 1 month–60 years - NCT05007990Recruiting
Interview study of caregiving networks over a person’s life
This study uses interviews and questionnaires to better understand who makes up a caregiver’s support network when caring for someone with a long-term health condition. Your answers may help researchers understand how caregiving changes over time and across different health situations.
Bethesda, MarylandAges 18–100 - NCT05223530Recruiting
Study of how pregnancy programs future child health
This study follows mothers who previously joined two specific pregnancy research programs, to understand why some children may be more likely to develop weight and heart-related health problems later. If you were part of those original studies, your information could help researchers look for early predictors and prevention ideas.
HelsinkiAges 11–55 - NCT05305287RecruitingPhase 4
Study how energy use in the liver works in people with fatty liver and diabetes
This trial measures how your liver cells use energy (mitochondrial function) in people with type 2 diabetes and fatty liver. It aims to better understand what is happening in the liver and how disease severity may relate to diabetes.
San Antonio, TexasAges 18–80 - NCT05533749Recruiting
E-Health coaching to improve health habits in severe mental illness
This study tests an online (eHealth) program to help people with severe mental illness improve physical health and everyday lifestyle behaviors. If you’re eligible, you’ll be asked to use the internet program and complete questionnaires.
The Hague, South HollandAges 18–65 - NCT05693701Recruiting
Lifestyle and study program for blood donors with high cholesterol
This study tests a multicomponent program for people who donate blood and have high cholesterol that fits familial hypercholesterolemia criteria. It may help lower cholesterol, but you must not already be on cholesterol-lowering medicines.
Dallas, TexasAges 18–75 - NCT05862454Recruiting
Magnesium shots may help avoid steroid during certain immune health issues
This trial studies whether giving a magnesium injection can replace (or avoid) steroids during treatment around times of vaccine, a viral infection, or immune system weakness. It targets adults with long-term (chronic) pain who already receive injection-based treatments and can reliably track symptoms.
Surrey, British ColumbiaAges 20–99 - NCT06046651Recruiting
Blood sample collection for lab research
This study collects blood samples from healthy adults to help researchers learn more about how to run lab tests. It involves one visit or at-home collection and might help future medical research.
San Francisco, CaliforniaAges 18 years+ - NCT06334172Recruiting
Can oxytocin control blood sugar?
This trial tests if the hormone oxytocin helps control blood sugar levels. It may offer insight into new ways to manage glucose. You may be a good fit if you are a healthy adult with a normal BMI.
Hellerup, Capital RegionAges 20–50 - NCT06383208Recruiting
Heart and kidney risk study for people with both diseases
This study looks at how well we can predict heart and kidney problems in people who have both coronary heart disease and chronic kidney disease. By analyzing certain markers, researchers hope to create a better risk assessment tool.
Beijing, Beijing MunicipalityAges 18–80 - NCT06494488RecruitingEarly Phase 1
Testing how omega-3s affect heart health and blood clotting
This study tests whether two types of omega-3s (EPA and DHA) help improve HDL (good cholesterol) and reduce blood clot risk in people with high triglycerides and low HDL cholesterol.
Providence, Rhode IslandAges 18–69 - NCT06535789RecruitingPhase 2/Phase 3
Inhaled insulin vs injections for gestational diabetes
This trial compares an inhaled insulin (Afrezza) to insulin injections for managing blood sugar after meals in women with gestational diabetes. The goal is to see if the inhaled option works as well and is easier to use.
Santa Barbara, CaliforniaAges 18–40 - NCT06612411RecruitingEarly Phase 1
Testing a probiotic for diarrhea-predominant IBS
This trial tests whether a specific probiotic (Bacillus subtilis) can help relieve symptoms in people with diarrhea-predominant irritable bowel syndrome (IBS). The study also looks at whether the probiotic works by increasing a natural chemical called hypoxanthine in the body.
NanjingAges 16–80 - NCT06660524RecruitingPhase 4
Calcium-phosphorus therapy for heart valve disease
This trial tests a treatment to lower high calcium and phosphorus levels in your blood, which may slow down calcium buildup in heart valves. It may help people with kidney problems who have valve disease.
Beijing, Beijing MunicipalityAges 50 years+
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Common questions
- Are there clinical trials for metabolic disorders?
- Yes. Clin2 currently lists 133 recruiting metabolic disorders studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a metabolic disorders trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a metabolic disorders trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.