Clinical trials
Microbiota clinical trials
Below are recruiting microbiota clinical trials, each written for real people, not researchers. We’re tracking 409 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07471373Recruiting
Pesticides and infertility study in endometriosis
This study looks at how pesticides might affect fertility in women with endometriosis, focusing on stress markers and gut/genital bacteria. You will provide samples and answer questions so researchers can compare women with and without endometriosis.
SalouëlAges 18–43 - NCT07212361Recruiting
Restoring infant gut bacteria with mother's microbes
This study tests whether giving healthy newborns a special mix of their own mother's friendly bacteria can help build a healthy gut. It is for mothers who had a healthy pregnancy, plan to breastfeed, and live near Helsinki.
HelsinkiAges Up to 50 years - NCT06289270Recruiting
Bladder cancer and urine bacteria study
This study looks at bacteria in urine and the bladder to understand if they play a role in causing bladder cancer. Researchers will compare samples from men with bladder cancer and healthy controls.
Cairo, Giza GovernorateAges 18 years+ - NCT04706611Recruiting
Stool transplant to treat gut and immune-related conditions
This trial studies fecal microbiota transplantation (a stool-based treatment) to improve symptoms and safety in people with certain gut and immune conditions. It aims to see whether changing gut bacteria can help you feel better.
Guangzhou, GuangdongAges 18–70 - NCT06205862RecruitingPhase 2
Fecal transplant for preventing colon polyp return
This study tests whether taking capsules of healthy bacteria (fecal microbiota transplant) can help prevent colon polyps from coming back after they have been removed. It might be an option for people who have had an adenoma polyp removed and want to reduce the chance of recurrence.
Guangzhou, GuangdongAges 18–75 - NCT07124260Recruiting
Gut and tongue bacteria study for low ovarian reserve
This study looks at the bacteria in your gut and on your tongue to see if they are different in women with low ovarian reserve. It may help doctors find new ways to understand and treat this condition.
Hangzhou, ZhejiangAges 20 years+ - NCT06782880Recruiting
Fecal transplant to prevent infections after liver transplant
This study tests if giving a fecal transplant (a procedure that transfers healthy bacteria from a donor's stool into your gut) before a liver transplant can lower the risk of serious infections after the surgery. It might help strengthen your immune system to fight off germs.
BolognaAges 18 years+ - NCT06106685RecruitingPhase 1/Phase 2
Washed microbiota transplant for chronic constipation
This trial tests a treatment called washed microbiota transplantation (a procedure that delivers healthy gut bacteria to your colon) for adults with chronic constipation. The goal is to see if it can improve bowel movements without the need for laxatives.
Nanjing, JiangsuAges 18–70 - NCT06282952Recruiting
Stool transplant for C-section babies' health
This trial tests whether giving a special stool transplant (fecal microbiota) to healthy babies born by C-section can improve their health. It aims to see if this treatment helps replace good bacteria that are normally passed during a vaginal birth.
OuluAges birth–6 hours - NCT03613545RecruitingPhase 2/Phase 3
Fecal transplant to treat irritable bowel syndrome
This study tests whether transferring stool bacteria from a healthy donor (fecal microbiota transplantation) can improve symptoms of irritable bowel syndrome (IBS). It may help by changing the gut bacteria that can influence digestion and gut discomfort.
Guangzhou, GuangdongAges 18–75 - NCT03804931RecruitingPhase 2/Phase 3
Stool transplant for moderate to severe ulcerative colitis
This trial tests whether transplanting stool bacteria into the colon (fecal microbiota transplantation) can improve ulcerative colitis symptoms in people with active, moderate to severe disease. If you qualify, the study team will also check that it’s safe for you and that you can safely undergo a scope exam.
Guangzhou, GuangdongAges 18–65 - NCT04924712Recruiting
Study of immune cells and gut germs in nephrotic flare-ups
This trial looks at how immune cells and gut (microbiota) changes relate to nephrotic syndrome flare-ups, and how a treatment approach may help during active attacks. You may be able to take part if you’re currently having a flare with high protein in your urine and meet key safety rules.
Nantes, Loire-AtlantiqueAges 12 years+ - NCT05690048RecruitingPhase 2
Fecal transplant to help liver cancer respond to standard drugs
This trial studies whether a fecal microbiota transfer (a “gut bacteria transfer” from a donor) can help liver cancer patients overcome resistance to atezolizumab and bevacizumab. It aims to improve how well the standard medicines control the cancer.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT05776914RecruitingPhase 2
Fecal transplant to treat moderate to severe IBS symptoms
This trial tests whether putting stool (fecal microbiota) from a donor into your bowel can improve symptoms in people with IBS who are not IBS-C. It may help by changing the gut bacteria that can influence IBS symptoms.
Rochester, MinnesotaAges 18–70 - NCT05821010RecruitingPhase 2
Synbiotics and fecal transplant for non-alcoholic liver inflammation
This Phase 2 study tests whether taking special gut-helping products (synbiotics) and/or a fecal microbiota transplant can improve non-alcoholic steatohepatitis (NASH), a type of liver inflammation. It may help by changing gut bacteria that may affect liver health, but you must meet specific safety and medical criteria.
Amsterdam, North HollandAges 18–75 - NCT07683936RecruitingEarly Phase 1
Fecal transplant for brain issues after liver procedure
This trial tests if transferring healthy bacteria into your gut (fecal microbiota transplant) can help people who still get confusion episodes (hepatic encephalopathy) even after a TIPS procedure and while on standard medications like lactulose and rifaximin.
Xi'anAges 18–75 - NCT07154784Enrolling by invitationPhase 2/Phase 3
Fecal transplant for long-term ulcerative colitis treatment
This trial tests whether fecal microbiota transplantation (FMT) can safely and effectively treat mild to moderate ulcerative colitis over the long term. FMT involves transferring stool from a healthy donor to restore a healthy balance of gut bacteria.
Seoul, Dongjak-guAges 10–80 - NCT06785922Enrolling by invitation
Stomach bacteria differences in H. pylori patients
This trial compares the types of bacteria in the stomach of people infected with different strains of H. pylori (CagA positive vs. negative). It may help researchers understand how these bacteria affect health.
Bangkok Noi, BangkokAges 18 years+ - NCT06182293Recruiting
Mouth bacteria in early systemic sclerosis
This study looks at the bacteria in the mouth (periodontal microbiota) of people with early systemic sclerosis compared to those without the condition. It may help understand if there is a link between oral health and systemic sclerosis.
StrasbourgAges 18 years+ - NCT06218602RecruitingPhase 2
Fecal transplant for lymphoma patients getting CAR T therapy
This trial tests whether giving a fecal transplant (a stool enema from a healthy donor) can improve the response to CAR T-cell therapy in people with B-cell lymphoma. It may help by restoring healthy gut bacteria that are often wiped out by strong antibiotics.
Houston, TexasAges 18 years+ - NCT05829109RecruitingEarly Phase 1
Stool transplant for long-term inflamed pouch after surgery
This early-phase study tests fecal microbiota transplant (a stool-based treatment) to improve chronic pouchitis symptoms in adults after UC-related surgery. It may help by changing gut bacteria, especially for people who need ongoing antibiotics or keep having flare-ups.
New York, New YorkAges 18 years+ - NCT07762729Enrolling by invitation
Gut bacteria and metabolic health in children over 3 years
This study looks at how the bacteria in the gut (gut microbiota) relate to metabolic health in children over a 3-year period. By participating, you will help researchers understand early development, and you'll receive regular health check-ups.
Yiyang, HunanAges birth–3 years - NCT07746635Recruiting
Fecal transplant for obese women with polyendocrine metabolic ovarian syndrome
This study tests whether a fecal microbiota transplant (a transfer of healthy gut bacteria) can help women with polyendocrine metabolic ovarian syndrome who are also overweight or obese and planning a frozen embryo transfer. It aims to see if this treatment can improve hormone balance and possibly increase the chance of a successful pregnancy.
Shanghai, Shanghai MunicipalityAges 20–40 - NCT07755111Recruiting
Breathing and tongue exercises for children's mouth bacteria
This trial tests if simple breathing and tongue exercises can help improve the bacteria in children's mouths. It includes children ages 7-12 who breathe through their mouth or nose.
Istanbul, BahcelievlerAges 7–12
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Common questions
- Are there clinical trials for microbiota?
- Yes. Clin2 currently lists 409 recruiting microbiota studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiota trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiota trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.