Clinical trials
Microbiota clinical trials
Below are recruiting microbiota clinical trials, each written for real people, not researchers. We’re tracking 409 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03732131Recruiting
Study of stool bacteria transplant to help people with infections
This study looks at fecal microbiota transplantation (FMT), which is a stool bacteria transplant, to help adults whose symptoms persist or return, often from C. difficile infection. If you’re already planning or receiving FMT for certain conditions, this trial may add information on how it helps and who benefits.
LahtiAges 18–120 - NCT06321536RecruitingPhase 2
Testing microbiota therapy for resistant bacteria in the gut
This study tests a treatment made from healthy donor stool (called microbiota therapy) given as an enema or through a feeding tube. It aims to help people who carry resistant bacteria that are hard to treat, by reducing or clearing those bacteria from the gut.
Atlanta, GeorgiaAges 18 years+ - NCT06159244Recruiting
Gut bacteria in severe alcoholic hepatitis
This trial looks at the gut bacteria (microbiome) in people with severe alcoholic hepatitis to understand how it affects the illness. It may help doctors find better ways to treat this condition.
Amiens, PicardieAges 18–75 - NCT04926103Recruiting
Fecal transplant program for active ulcerative colitis donors
This trial screens people as potential donors for a fecal microbiota transplant program used for ulcerative colitis. It checks safety and eligibility so the transplant process is as safe as possible for people with active disease.
Hamilton, OntarioAges 18 years+ - NCT03819803RecruitingPhase 3
Fecal transplant for gut graft-versus-host disease
This study tests whether restoring healthy gut bacteria using a fecal microbiota transplant can improve steroid-refractory gut graft-versus-host disease (aGvHD) after stem cell transplant. If your gut symptoms are your first episode and your stool bacteria diversity is low, this trial may be an option worth screening for.
Graz, StyriaAges 18–70 - NCT04623424Recruiting
Study gut bacteria during stem cell transplant
This study looks at changes in your gut bacteria (microbiome) around the time of stem cell transplant. The goal is to understand how these bacteria relate to transplant outcomes, which may help doctors improve care in the future.
Detroit, MichiganAges 18–80 - NCT02543866RecruitingPhase 1
Fecal transplant to clear resistant gut bacteria in children
This Phase 1 study tests whether transferring stool microbiome (a fecal microbiota transplant) can help clear antibiotic-resistant bacteria living in the gut. It’s meant for children and teens who have had infections from these resistant bacteria and who can safely take the study’s planned treatment.
Seattle, WashingtonAges 7–21 - NCT01868373Enrolling by invitationPhase 1
Fecal transplant study for hard-to-treat C. difficile diarrhea
This Phase 1 study tests defined fecal microbiota (healthy gut bacteria) given to people with C. difficile diarrhea that didn’t go away or came back soon after antibiotics. It may help by restoring a healthier balance of gut bacteria so the infection can stop recurring.
Houston, TexasAges 18 years+ - NCT03516461Recruiting
Fecal transplant study for bowel injury after radiation
This study tests whether transferring stool bacteria (a fecal microbiota transplant) can improve “radiation enteritis,” a bowel problem that happens after radiation treatment. It may help restore gut bacteria and reduce symptoms after your radiation therapy.
Nanjing, JiangsuAges 18–85 - NCT07529119Recruiting
Mango and Chia Drink Effects on Gut Health in Children
This study tests whether a special drink made with mango and chia seeds can improve gut bacteria health in children who are overweight or obese. Researchers want to see if this drink might help with weight and digestion.
Coronel OviedoAges 8–16 - NCT06262451Enrolling by invitation
Fecal transplant national registry study
This study creates a registry for people who receive fecal microbiota transplants (FMT) to track long-term safety and outcomes. It may help researchers understand how this treatment works over time.
San Francisco, CaliforniaAges Any age - NCT06513416Recruiting
Gut bacteria and lung problems after surgery in older adults
This study tests whether the bacteria in your gut are linked to lung complications after a long abdominal surgery. If you are 65 or older and having a scheduled upper abdominal surgery, researchers want to understand how your microbiome affects your recovery.
Beijing, Beijing MunicipalityAges 65 years+ - NCT06479941Recruiting
Antibiotics in pregnancy and baby's gut health
This study looks at how antibiotics taken during pregnancy might affect the bacteria in your baby's gut. Researchers want to learn if this early exposure influences your baby's health.
BeijingAges 1 day–1 year - NCT07094984Recruiting
Clearing resistant gut bacteria: three FMT methods
This trial tests three different ways to clear antibiotic-resistant bacteria from your gut using fecal microbiota transplant (FMT). It may help if you have a confirmed resistant infection and are looking for a treatment to reduce the risk of future infections.
WarsawAges 18 years+ - NCT07388121Recruiting
Vitamin C and gut health in healthy adults
This trial tests whether taking vitamin C supplements changes the bacteria in your gut and how well your gut works. If you are a healthy adult, you may be able to join.
GlasgowAges 18–65 - NCT07387952Recruiting
Fecal transplant with nutrition help for chronic constipation
This trial tests if a fecal microbiota transplant combined with nutritional support can improve chronic constipation that hasn't gotten better with standard treatments. It's a small early study to see if the approach is safe and works.
BeijingAges 18–70 - NCT06346093Recruiting
Fecal transplant for advanced stomach cancer
This trial tests whether a fecal transplant (a stool donation from a healthy person) can help patients with advanced stomach cancer respond better to treatment. If you qualify, you would receive the transplant through a colonoscopy, possibly along with other standard therapies.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07276100RecruitingPhase 2
Fecal transplant to help liver cancer that worsened on first treatment
This trial tests whether transplanting healthy stool bacteria into your gut can help your own immune system fight liver cancer that has stopped responding to the standard first combination treatment (atezolizumab + bevacizumab). It is for patients whose liver cancer has started growing quickly despite that treatment.
Bologna, BOAges 18 years+ - NCT05067595RecruitingPhase 1
Fecal transplant plus fiber for gut graft-versus-host disease
This Phase 1 study tests whether a fecal microbiota transplant (a stool-based treatment from a screened donor) plus a dietary fiber supplement can improve gut symptoms after a bone marrow transplant. It is aimed at people with mild to severe gut graft-versus-host disease (GVHD).
Seattle, WashingtonAges 18 years+ - NCT06532110Recruiting
Gut bacteria study in chronic digestive diseases
This study looks at the bacteria in your gut (the microbiome) in people with chronic gut conditions. Researchers want to understand how gut bacteria differ in these conditions to help improve treatments.
Hamilton, OntarioAges 18–75 - NCT07624409Enrolling by invitationEarly Phase 1
Occupational health study for high-altitude workers
This study examines how working at high altitudes (where there is less oxygen in the air) affects employees at an astronomical observatory in Chile. Researchers want to understand health impacts and develop better support for people working in these extreme conditions.
San Pedro de Atacama, AntofagastaAges 20–50 - NCT06931808Enrolling by invitationPhase 4
Fecal transplant with chemo, radiation, and immunotherapy for advanced colon cancer
This study tests a combination of fecal microbiota transplant, chemotherapy, radiation, and immunotherapy (sintilimab) for people with locally advanced rectal cancer. The goal is to see if this approach improves treatment outcomes.
Ningbo, ZhejiangAges 18–75 - NCT07606053Enrolling by invitation
Endometrial Microbiota and IVF Success
This study examines whether the bacteria living in the uterine lining (endometrium) affect whether embryos implant and pregnancies continue after IVF. Researchers will collect tissue samples and study your microbiota—the community of microorganisms in your body—to help explain repeated implantation failures or miscarriages.
ThessalonikiAges 18–54 - NCT06730451Recruiting
Fecal transplant for gut health after organ transplant
This trial tests whether fecal microbiota transplantation (Washed Microbiota Transplantation, or WMT) can help people who have gut problems like diarrhea, constipation, or infection after receiving a solid organ transplant. It aims to restore healthy gut bacteria.
Nanjing, JiangsuAges Any age
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Common questions
- Are there clinical trials for microbiota?
- Yes. Clin2 currently lists 409 recruiting microbiota studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiota trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiota trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.