Clinical trials
Oral Microbiota clinical trials
Below are recruiting oral microbiota clinical trials, each written for real people, not researchers. We’re tracking 23 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07755111Recruiting
Breathing and tongue exercises for children's mouth bacteria
This trial tests if simple breathing and tongue exercises can help improve the bacteria in children's mouths. It includes children ages 7-12 who breathe through their mouth or nose.
Istanbul, BahcelievlerAges 7–12 - NCT05943197Recruiting
Microbiology-focused choice of joint prosthetic material
This trial focuses on using lab testing (microbiology) to help choose the best material for a prosthetic used in orthopedic treatment. If you need a prosthetic, this could help doctors select a material more tailored to your situation.
SamaraAges 1 month–1 month - NCT07015580Recruiting
Mouth bacteria in pancreatitis types
This study looks at the bacteria in your mouth to see if they are different in chronic pancreatitis and autoimmune pancreatitis. It might help doctors understand these diseases better.
Shanghai, Shanghai, ChinaAges 18 years+ - NCT07162662Recruiting
How Oral Sialic Acid Affects Gut Bacteria in Healthy People
This trial tests whether taking a supplement called sialic acid can change the bacteria in your gut in a healthy way. It is for adults who are generally healthy and not taking medications that affect digestion or metabolism.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT05690048RecruitingPhase 2
Fecal transplant to help liver cancer respond to standard drugs
This trial studies whether a fecal microbiota transfer (a “gut bacteria transfer” from a donor) can help liver cancer patients overcome resistance to atezolizumab and bevacizumab. It aims to improve how well the standard medicines control the cancer.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT07069140Recruiting
Lactoferrin mouthwash for gum health during pregnancy
This study tests if a daily lactoferrin mouthwash can improve gum health in pregnant women with gum disease, without needing antibiotics or other treatments. Researchers want to see if this natural protein helps keep gums healthier during the second trimester.
Pavia, LombardyAges 18–45 - NCT07597213Recruiting
Hyaluronic acid to help gum disease treatment in smokers
This study tests whether adding hyaluronic acid (a natural substance) to standard gum disease treatment helps smokers recover better. Gum disease is serious in smokers, and this treatment might improve healing.
IstanbulAges 18–65 - NCT06824493Recruiting
How Braces Affect Mouth Bacteria and Saliva
This study looks at how braces (orthodontic treatment) change the bacteria and proteins in your mouth. Healthy volunteers who have never had dental work or cavities are needed to provide saliva samples before and during treatment.
Xi'an, ShaanxiAges 6–18 - NCT05232331Recruiting
Eat nitrate-rich vegetables to study gum inflammation and mouth bacteria
This study looks at whether eating more nitrate-rich vegetables changes inflammatory markers and the balance of bacteria in the mouth for people with periodontitis (serious gum disease). It may help us understand better diet-based support alongside standard non-surgical gum treatment.
Guadalajara, JaliscoAges 30–65 - NCT07476703Recruiting
Extended study on the SCAPIS Stockholm reexamined group
This trial studies data and samples from people already taking part in the main SCAPIS reexamination study in Stockholm. It looks for new findings to help understand heart and lung health.
StockholmAges 56–74 - NCT06197308RecruitingEarly Phase 1
Testing a mouth bacteria treatment for PSC
This study tests whether a treatment made from mouth bacteria can help people with primary sclerosing cholangitis (PSC). It aims to see if it's safe and improves health.
Minneapolis, MinnesotaAges 18–76 - NCT07746635Recruiting
Fecal transplant for obese women with polyendocrine metabolic ovarian syndrome
This study tests whether a fecal microbiota transplant (a transfer of healthy gut bacteria) can help women with polyendocrine metabolic ovarian syndrome who are also overweight or obese and planning a frozen embryo transfer. It aims to see if this treatment can improve hormone balance and possibly increase the chance of a successful pregnancy.
Shanghai, Shanghai MunicipalityAges 20–40 - NCT05695261RecruitingPhase 2
Oral microbiome capsules for peanut allergy in teens
This Phase 2 study tests whether taking capsules made from donor gut microbes is safe and can reduce allergic reactions to peanuts. It involves peanut allergy testing and close follow-up with stool samples and check-ins.
Boston, MassachusettsAges 12–17 - NCT04105270RecruitingPhase 2
Durvalumab plus chemo with RMT for lung cancer
This Phase 2 trial studies a new treatment plan that combines RMT with durvalumab and chemotherapy in people with untreated advanced lung adenocarcinoma. It aims to improve outcomes by helping the immune system and fighting cancer cells together.
Phoenix, ArizonaAges 18 years+ - NCT05266807RecruitingPhase 3
Capsule fecal transplant to prevent C. difficile coming back
This study tests whether taking a capsule form of fecal microbiota transplant (FMT) can help adults with their first C. difficile infection—or a first relapse—get better and reduce repeat episodes. Participants also take specific antibiotics for C. difficile as part of the study process.
Basel, BaselAges 18 years+ - NCT04373473RecruitingPhase 2
Oral stool treatment to prevent ulcerative colitis flare-ups
This study tests whether taking freeze-dried (lyophilized) donor stool material by mouth can help prevent ulcerative colitis from coming back or causing intestinal inflammation. Participants are in remission and stay on their usual treatment while receiving the study product.
Houston, TexasAges 18 years+ - NCT06347770RecruitingPhase 1
Oral Gan Shuangbi for recovery after C-section
This trial tests an oral herbal medicine (Gan Shuangbi) to see if it helps your intestines work normally again after a C-section. It may speed up recovery after delivery.
Guangzhou, GuangdongAges 18–45 - NCT06692179RecruitingPhase 1
Testing a freeze-dried fecal transplant during colon surgery
This trial tests if giving a special freeze-dried mixture of healthy gut bacteria right after colon surgery is safe and possible. It may help patients recover better after the procedure.
Minneapolis, MinnesotaAges 18–75 - NCT05830591Recruiting
Gut microbiome study in autism in children
This trial studies differences in the gut bacteria (microbiome) between children with autism and healthy children. It may help researchers understand what roles the gut may play in autism and guide future treatments.
TriesteAges 1–17 - NCT04046900RecruitingPhase 1/Phase 2
Fecal-style transplant of vaginal microbiome for recurring BV
This trial tests whether transplanting “good bacteria” into the vagina can treat recurrent bacterial vaginosis (BV). It may help restore a healthier vaginal bacterial balance and reduce BV episodes.
Boston, MassachusettsAges 18–50 - NCT04792320Recruiting
Probiotics and fiber for kidney disease with leg artery blockage
This study tests whether an oral absorbent plus probiotics can improve gut health and circulation in people who have chronic kidney disease and symptomatic peripheral artery disease (PAD). It will also track changes in blood markers and how well blood vessels function.
TaipeiAges 20 years+ - NCT07065942Recruiting
Lactulose for gut health in diabetes with constipation
This study tests if a common stool softener called lactulose can improve gut health and metabolism in people with type 2 diabetes and long-term constipation. It aims to see if changing gut bacteria can help both digestion and blood sugar control.
BeijingAges 18–70 - NCT05303337Recruiting
Study of gut and HIV changes after switching to long-acting shots
This trial compares how HIV “reservoirs,” inflammation, and the gut microbiome change when people switch from daily HIV pills to long-acting injectable treatment. It may help you and your team understand what to expect with the switch and how your body responds.
MarseilleAges 18 years+
Hear when a new Oral Microbiota trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for oral microbiota?
- Yes. Clin2 currently lists 23 recruiting oral microbiota studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a oral microbiota trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a oral microbiota trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.