Clinical trials
Microbiota clinical trials
Below are recruiting microbiota clinical trials, each written for real people, not researchers. We’re tracking 408 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07264998Recruiting
Gut bacteria study in breast cancer patients on Abemaciclib
This study looks at how gut bacteria changes in people taking Abemaciclib (a breast cancer drug) and whether that relates to diarrhea. It may help find ways to prevent or manage this side effect.
Wuhan, HubeiAges 18–75 - NCT07283328Recruiting
Methionine and Gut Bacteria Study in Healthy Adults
This study looks at how a diet low in methionine (a protein building block) affects the bacteria in your gut.
Montreal, QuebecAges 20–50 - NCT07287306Recruiting
Probiotic study on gut health in healthy adults
This trial tests two probiotics, BLa80 and LRa05, to see how they affect the gut's natural bacteria and related substances. It may help understand how these probiotics support overall health.
Guangzhou, GuangdongAges 18–60 - NCT07300553RecruitingPhase 2
Gut bacteria and energy metabolism in health and IBD
This study looks at how the bacteria living in your gut affect your body's energy use. It includes both healthy volunteers and people with inactive Crohn's disease or ulcerative colitis.
ParisAges 18–50 - NCT07306988RecruitingPhase 4
Treating H. pylori to improve metabolic syndrome
This trial tests whether treating H. pylori infection can help improve metabolic syndrome (a group of conditions like high blood sugar, abnormal cholesterol, and high blood pressure). It aims to understand how treatment changes your gut bacteria and overall health.
Nanjing, JiangsuAges 18–65 - NCT07329595Recruiting
Tracking gut bacteria changes after severe burns
This study looks at how severe burns change the bacteria in your gut and your immune system. It will track these changes to better understand recovery and find new ways to help healing.
Debrecen, Hajdú-BiharAges 18–65 - NCT07333482Recruiting
Flourish: How gut bacteria grow in C-section babies
This study looks at the gut bacteria of infants born by C-section. Researchers want to learn how the microbiome develops in healthy babies who have not taken probiotics.
Austin, TexasAges birth–3 months - NCT07334210Recruiting
Gut bacteria in sarcopenia and probiotic development
This study looks at gut bacteria differences between older adults with muscle loss (sarcopenia), healthy older adults, and younger adults. Results may help develop probiotics to support muscle health.
Seongnam-si, Gyeonggi-doAges 20–90 - NCT07342205RecruitingPhase 2/Phase 3
Fecal transplant for sepsis-related lung injury
This study tests if transferring healthy gut bacteria (fecal microbiota transplant) can help people with acute lung injury caused by sepsis. It aims to reduce inflammation and improve breathing.
Shanghai, PutuoAges 18 years+ - NCT07342621Recruiting
Testing a special formula for babies with cow's milk allergy
This study tests whether a special formula with added prebiotics, probiotics, and a human milk nutrient helps manage symptoms in infants with cow's milk protein allergy. If your baby is starting a hypoallergenic formula for the first time, this trial may be an option.
Valencia, ValenciaAges Up to 10 months - NCT07363304Recruiting
How ETI therapy affects body and gut in cystic fibrosis
This study looks at how the triple combination therapy (elexacaftor/tezacaftor/ivacaftor, or ETI) affects your body's metabolism, epigenetics, and gut bacteria in people with cystic fibrosis. It aims to understand the broader health benefits of this treatment.
Bari, BariAges 2 years+ - NCT07363551Recruiting
Omega-3 for depression in young people
This trial tests if omega-3 fatty acid supplements can improve depression in young people by reducing inflammation and changing gut bacteria. You may be eligible if you are a young person with a current major depressive episode.
Taichung, TaichungAges 13–18 - NCT07369830Recruiting
Probiotics for bowel function after rectal cancer surgery
This trial tests whether taking a probiotic supplement (Clostridium butyricum) can improve gut health and bowel function after surgery for very low rectal cancer. It may help patients who have a temporary ileostomy and are planning to have it reversed within 6 months.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07374094Recruiting
Understanding C. difficile infection and treatment effects
This study is tracking patients with a confirmed C. difficile infection to understand how the body responds and how treatments work. You may be asked to do follow-up visits for up to 5 years.
UmeåAges 18 years+ - NCT07381374Recruiting
Fecal transplant for children with autism
This trial tests whether fecal microbiota transplantation can help children with moderate-to-severe autism. It involves giving healthy donor bacteria to improve gut health and possibly autism symptoms.
Shenzhen, GuangdongAges 3–16 - NCT07385807Recruiting
Gut health and pregnancy in inflammatory bowel disease
This study looks at gut health in pregnant women with and without inflammatory bowel disease (IBD). It tracks a protein called calprotectin in stool samples, along with diet and baby health, to learn how IBD affects pregnancy and infant development.
Vancouver, British ColumbiaAges 19 years+ - NCT01793831Recruiting
Fecal transplant study for people with Crohn’s disease
This study tests whether a standardized stool-based treatment (fecal microbiota transplantation) can help people with Crohn’s disease. You may qualify if your Crohn’s diagnosis has been stable and you’re willing to receive the fecal transplant.
Huai'an, JiangsuAges Any age - NCT01905709Recruiting
Fecal transplant to treat recurring C. difficile infection
This trial studies using a fecal microbiota transplant (FMT)—healthy gut bacteria moved from a screened donor—to help treat recurring or hard-to-control C. difficile infection. It may help restore a healthier gut environment when standard treatments keep failing or the infection returns.
Englewood, New JerseyAges 18 years+ - NCT02127398RecruitingPhase 2
Fecal transplants for hard-to-treat C. difficile infection
This Phase 2 study tests whether placing stool from a healthy donor into your gut can treat repeated, hard-to-control C. difficile colitis. It may help restore healthy gut bacteria and reduce future flare-ups.
Durham, North CarolinaAges 18 years+ - NCT02573753Recruiting
Study how sleep affects gut bacteria and health
This study looks at how different sleep patterns change the microorganisms in your gut (gut bacteria) and what that may mean for health. It’s mainly for people who can take part in other approved research studies at the same time.
Rochester, MinnesotaAges 18 years+ - NCT02636517Enrolling by invitationPhase 1
Fecal microbiome transplant for repeat C. difficile infection
This Phase 1 study tests whether transferring healthy gut bacteria (a fecal microbiome transplant) can help children with repeated or moderate-to-severe C. difficile infection. It focuses on changing gut bacteria to reduce ongoing infection and symptoms.
Philadelphia, PennsylvaniaAges 3–21 - NCT07408479Recruiting
How starch digestion affects blood sugar and health in insulin resistance
This trial studies how different types of starch (carbohydrates) affect blood sugar control, inflammation, and gut health in people with insulin resistance. You may benefit if you are overweight, have insulin resistance, and are willing to follow a specific diet for 2 months.
LyonAges 18–75 - NCT07417085Recruiting
Study of gut bacteria in children with brain tumors
This study looks at how gut bacteria (the microbiome) may differ in children with brain tumors. Researchers will collect samples before and after surgery to understand the connection between gut health and brain tumors.
Florence, FirenzeAges 3–18 - NCT07429864Recruiting
Bulevirtide for hepatitis D: bile acids and gut bacteria
This study looks at how Bulevirtide, a treatment for hepatitis D, affects bile acids and gut bacteria. It may help patients with chronic HDV and stable liver disease who are already on HBV therapy.
RomaAges 18 years+
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Common questions
- Are there clinical trials for microbiota?
- Yes. Clin2 currently lists 408 recruiting microbiota studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a microbiota trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a microbiota trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.