Clinical trials
Migraine clinical trials
A neurological condition causing recurring, often disabling headaches. We’re tracking 190 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07567300Recruiting
Understanding Pain Patterns in Migraine and Neck or Back Pain
This study explores how migraine headaches, neck pain, and lower back pain may share similar pain mechanisms in the body. Researchers will ask you questions to understand your pain patterns and help identify connections between these conditions.
Gaziantep, MerkezAges 18–65 - NCT07301008RecruitingPhase 4
Rimegepant to prevent predictable trigger-induced migraines
This trial tests whether a medication called rimegepant can prevent migraines when you take it before a known trigger (like exercise or stress). It is for people who get migraines often and can predict when one might happen.
McLean, VirginiaAges 18 years+ - NCT07297901Enrolling by invitation
Breathing app study for migraine relief
This trial tests a smartphone-based breathing program to help reduce migraines. It uses heart rate data to guide breathing exercises tailored to you.
Phoenix, ArizonaAges 18 years+ - NCT06882122Recruiting
Atogepant for episodic migraine: brain and body effects
This study tests a daily pill called atogepant to see how it affects the brain and body in people with episodic migraine. It may help if you have 8 to 14 migraine days a month and haven't tried CGRP treatments before.
Pavia, PAVIAAges 18–70 - NCT07233941Recruiting
Cognitive and psychological study in migraine patients
This study looks at thinking abilities and psychological factors in people with migraines. It aims to understand how migraine affects memory, attention, and emotions.
MilanAges 18–65 - NCT07103694Recruiting
Migraine drug database study
This study is building a database to learn more about migraine drugs. It may help researchers find better treatments for people with episodic or chronic migraine.
Milan, ItalyAges 18 years+ - NCT07040813RecruitingPhase 3
Two migraine medicines together for chronic migraine
This trial tests whether using both a CGRP antibody and Botox together works better than the CGRP antibody alone for chronic migraine. It may help if you have not tried these treatments before.
GrålumAges 18–70 - NCT07021859Recruiting
Migraine with aura study using CGRP to trigger attacks
This study tests whether a substance called CGRP (a protein linked to migraines) can safely trigger a migraine with aura in people who already have this condition. You'll receive an infusion and be monitored to see how your body responds.
Glostrup MunicipalityAges 18–65 - NCT06967909Recruiting
Tai Chi vs. Acupuncture for Migraine Prevention
This study compares Tai Chi and acupuncture to see which is better at preventing migraines and improving brain health. If you are a Chinese woman in Hong Kong who gets migraines 2 to 14 days per month, you may be able to join.
Hung HomAges 18 years+ - NCT06507150Recruiting
AI-assisted migraine education for newly diagnosed patients
This study tests a new AI-powered learning tool to help people who were just diagnosed with migraine understand their condition better. You'll use the tool on your own device, and researchers will see if it's helpful and easy to use.
LuganoAges 18–65 - NCT06428838Enrolling by invitationPhase 3
Add-on migraine treatment for emergency room visits
This study tests an add-on migraine medicine (eptinezumab) given in the emergency room to quickly relieve a migraine attack, in addition to the usual care. It aims to see if this approach reduces pain and prevents the migraine from coming back.
New Westminster, British ColumbiaAges 19–75 - NCT06212661Enrolling by invitation
Study on migraine drugs and bladder symptoms
This study looks at how certain migraine treatments affect bladder symptoms like frequent or urgent urination. If you have hard-to-treat migraines and are starting a CGRP inhibitor or Botox injections, you may be able to join.
Cleveland, OhioAges 18 years+ - NCT04063540RecruitingPhase 2
Amiloride to prevent migraine aura episodes
This study tests whether amiloride can reduce how often migraine aura happens. It’s a proof-of-concept early study, meaning the main goal is to see if the approach seems to work and is safe for people with frequent aura.
BronAges 18–80 - NCT05654012Recruiting
Study of migraine risk in teens and kids
This study looks at how migraine may start or affect children by comparing young people who either have migraine symptoms or are at higher risk. It may help researchers understand migraine patterns and who could benefit from early prevention.
St Louis, MissouriAges 10–13 - NCT05334927Recruiting
Headache disorder registry for teens and adults with primary headaches
This study is a headache disorder registry that enrolls people with common, “primary” headache types such as migraine or tension headache, including some with medication-overuse headaches. It collects information to better understand these conditions and who they affect.
Anqing, AnhuiAges 12 years+ - NCT04965675RecruitingPhase 3
Eptinezumab for teens with chronic migraine
This trial tests eptinezumab, a preventive medicine, to reduce headache frequency in teens with chronic migraine. It may help your teen if they have frequent migraine days despite usual care.
New Haven, ConnecticutAges 12–17 - NCT07674654RecruitingPhase 3
Long-term safety study of an investigational migraine medication
This study is testing the long-term safety of an investigational migraine medication called elismetrep. It is for people who have already completed a previous study of this drug and are willing to continue using a smartphone app to track their symptoms daily.
Birmingham, AlabamaAges 18 years+ - NCT07871097RecruitingPhase 4
Rimegepant for acute vestibular migraine relief
This study tests a medication called rimegepant to see if it quickly relieves vertigo and dizziness during a vestibular migraine attack. Vestibular migraine causes symptoms like spinning or imbalance, often with headache. If you have frequent, moderate-to-severe episodes, this treatment might offer relief.
Wuhan, HubeiAges 18–60 - NCT07841509Recruiting
Remote electrical neuromodulation for migraine and fibromyalgia
This study tests a wearable device that uses gentle electrical signals to reduce pain in people with migraine or fibromyalgia. It may help by changing how the brain processes pain signals.
Bridgewater, New JerseyAges 18 years+ - NCT07816367RecruitingPhase 3
Elismetrep for treating migraine attacks
This study tests an investigational medicine called elismetrep (K-304) for treating migraine attacks quickly. If you have migraines, you take the medicine when a migraine starts and report how well it works.
Glendale, ArizonaAges 18–75 - NCT07769255Recruiting
Nebulized dexmedetomidine for early chronic migraine
This trial tests whether a medicine called dexmedetomidine, given through a nebulizer (mist you breathe in), can help reduce the number of headache days and prevent migraines from becoming chronic. It is for people who have recently started having many headache days each month.
Banī SuwayfAges 18–55 - NCT07762690Enrolling by invitation
Neck rehabilitation for chronic migraine
This study tests a neck exercise program designed to improve neck function and reduce migraine symptoms. It may help people whose migraines are linked to neck problems.
Banī Suwayf, EgyptAges 18–55 - NCT07743255Enrolling by invitation
Preventing migraines in children with melatonin and propranolol
This study tests whether two common medicines, melatonin and propranolol, can help prevent migraines in children. If your child has frequent, disabling migraines, this treatment might reduce how often they occur and improve daily life.
Multan, Punjab ProvinceAges 5–15 - NCT07729462RecruitingPhase 3
Rimegepant for preventing chronic migraine
This study tests whether the medication rimegepant can help prevent chronic migraine in adults. It may be an option if you have frequent migraines and have not tried certain other preventive treatments.
Scottsdale, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for migraine?
- Yes. Clin2 currently lists 190 recruiting migraine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a migraine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a migraine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.