Clinical trials
Migraine Headache, With or Without Aura clinical trials
Below are recruiting migraine headache, with or without aura clinical trials, each written for real people, not researchers. We’re tracking 193 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07325513Recruiting
Brain stimulation for Gulf War-related pain
This study tests whether a type of brain stimulation (repeated transcranial magnetic stimulation, or rTMS) can help reduce headaches and body pain in veterans with Gulf War Illness. If you are a Gulf War veteran with ongoing moderate-to-severe pain, this trial could help find a new way to manage your symptoms.
San Diego, CaliforniaAges 18–65 - NCT07328685Recruiting
Body awareness therapy for migraine relief
This trial tests a gentle therapy called Basic Body Awareness Therapy to see if it helps reduce migraine attacks. It focuses on improving how you sense and move your body, which may ease migraine symptoms.
Antakya, HatayAges 18–55 - NCT07354126Recruiting
Flunarizine vs. propranolol for migraine in children
This trial tests two medicines—flunarizine and propranolol—to see which one works better for preventing migraines in children ages 8 to 15. If your child has frequent migraines that affect their daily life, this study may help find a treatment that works for them.
Lahore, Punjab ProvinceAges 8–15 - NCT07360782Recruiting
Personalized nerve treatment for medication overuse headache
This trial tests a treatment called personalized pulsed radiofrequency, which uses gentle electrical pulses on a nerve at the back of your head to help reduce headaches caused by using too much pain medication. It is designed for people who have been diagnosed with Medication Overuse Headache and want a non-drug option.
AnkaraAges 18–65 - NCT07479082Recruiting
Ear nerve stimulation for headache after aneurysm coiling
This trial tests whether a gentle electrical device placed on your ear (called transcutaneous auricular vagus nerve stimulation) can help prevent or reduce headaches that sometimes happen after a procedure to treat an unruptured brain aneurysm. If you're scheduled for stent-assisted coiling or flow diverter treatment, this study may offer a non-drug option to manage post-surgery pain.
Beijing, Beijing MunicipalityAges 18–80 - NCT07508410Recruiting
Mulligan vs Myofascial Release for Neck-Related Headaches
This study compares two hands-on therapy techniques—Mulligan mobilization and myofascial release—to see which works better for headaches that start from the neck. If you have neck pain on one side and headaches that get worse with movement, this trial may help you find relief.
KonyaAges 18–65 - NCT07515456Recruiting
Comparing Three Medications for Spinal Headaches
This study tests three different medications—theophylline, sumatriptan, and gabapentin—to see which works best for headaches that occur after a spinal procedure. You would receive one of these treatments and be monitored to see how well it relieves your pain.
Tanta, El-GharbiaAges 21–50 - NCT07526025Recruiting
Neck exercises for headaches caused by neck problems
This study tests two types of neck exercises to treat headaches that start in the neck and travel to the head. The exercises focus on strengthening neck muscles and retraining how your neck moves to reduce pain.
Islamabad, Punjab ProvinceAges 18–45 - NCT07579481Recruiting
Vortioxetine for Depression with Migraine
This study tests whether vortioxetine, a depression medication, can help people who have both depression and episodic migraine (recurring headaches). You'd take vortioxetine for depression while researchers track how it affects both your mood and migraine symptoms.
Rome, LazioAges 18 years+ - NCT07626307Recruiting
Migraine Screening Tool to Guide Physical Therapy Referral
This study tests whether a simple assessment tool can help neurologists decide which migraine patients would benefit from physical therapy. You'll be evaluated by both a neurologist and a physical therapist to see if the tool correctly identifies patients who could improve with hands-on treatment.
MilanAges 18–70 - NCT07656922Recruiting
Shoulder muscle function and migraine
This study looks at how the muscles around your shoulder blade work during migraine attacks. It may help find better ways to treat migraine-related shoulder problems.
Ankara, ÇubukAges 18–55 - NCT07671703Recruiting
Physiotherapy for migraine relief
This trial tests whether a combination of physical therapy techniques can reduce migraine symptoms. It may help people whose migraines are not caused by other conditions.
Osnabrück, Low SaxonyAges 18–70 - NCT07553533Enrolling by invitation
Temporary Nerve Stimulation for Headache Relief
This trial studies a temporary nerve-stimulation device placed near the back of your head to treat chronic headaches. The device sends mild electrical pulses to help reduce headache pain over 60 days, and your doctor has already decided this treatment is right for you as part of your regular care.
New Haven, ConnecticutAges 18 years+ - NCT07493434Enrolling by invitation
Can essential oils help with migraine pain?
This trial tests if inhaling essential oils can reduce pain in people with migraine. You may join if you have migraines and are not allergic to essential oils.
São Paulo, São PauloAges 18–60 - NCT07310823Enrolling by invitation
Manual therapy for neck-related headaches
This study tests if manual therapy (hands-on treatment) can help people whose headaches start from neck problems. If you have headaches at least once a week and limited neck movement, this trial may be an option.
GizaAges 20–40 - NCT07168512Enrolling by invitation
Release technique and exercises for cervicogenic headache
This trial tests whether a gentle hands-on therapy called myofascial release, alone or with exercises, can improve the neck curve, sleep, and mood in people whose headaches come from a neck problem. If you have headaches that start from your neck, this might help you find relief.
Gaza, Gaza StripAges 20–55 - NCT07163559Enrolling by invitation
Coping skills program for migraine relief
This study tests a 6-month program that teaches coping skills to help manage migraine headaches. It may help you feel more in control of your symptoms.
Ankara, AltındağAges 18–65 - NCT06797414Recruiting
Pilates with or without vibration for upper cross syndrome
This study compares Pilates exercises with and without whole-body vibration (a platform that gently shakes your body) to see which better improves posture and pain in people with upper cross syndrome (a common pattern of rounded shoulders and forward head). It aims to find a more effective way to strengthen muscles and reduce discomfort.
Lahore, Punjab ProvinceAges 20–40 - NCT03694626Recruiting
Test a light-response study to measure and track light sensitivity
This study aims to objectively measure how your pupils respond to light and how your eye muscles react using recording tests. It may help confirm the cause of light sensitivity (especially after a brain injury) and better track how it responds to care.
Iowa City, IowaAges 18–80 - NCT05049057RecruitingPhase 2
Testing a nerve-blocking shot for recent mild TBI
This Phase 2 study tests a medication that blocks a pain signal (a CGRP receptor antibody) in people who recently had a mild traumatic brain injury (mTBI) and are also dealing with post-traumatic headache (PTH). The goal is to see if it can reduce symptoms and improve recovery after the injury.
Fort Bragg, North CarolinaAges 18–50 - NCT05752396Recruiting
Study of Pain Patterns Over Time in Kids
This study follows kids who have a specific type of chronic pain (headaches, stomach pain, or muscle/joint pain) to better understand how pain changes over time. It also checks whether certain factors are linked to those pain patterns.
Cincinnati, OhioAges 10–19 - NCT05814497Recruiting
Brain scan study of how kids process chronic pain
This study looks at how the brain processes pain sensations in children with certain long-lasting pain conditions. It may help researchers understand what’s happening in the nervous system and guide better treatments.
Cincinnati, OhioAges 10–17 - NCT07681466Recruiting
Study of early warning signs before migraines
This study looks at the early signs that happen before a migraine starts, such as fatigue or mood changes. It aims to help people understand their migraine patterns better.
Latina, ItalyAges 18–65 - NCT07639944Recruiting
REN Device Study for Jaw Pain and Headaches
This study tests whether a treatment called REN can help reduce headaches and jaw pain caused by temporomandibular disorders (TMD). You would use the REN device at home on your smartphone or tablet over several months.
Ridgeland, MississippiAges 12 years+
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Common questions
- Are there clinical trials for migraine headache, with or without aura?
- Yes. Clin2 currently lists 193 recruiting migraine headache, with or without aura studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a migraine headache, with or without aura trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a migraine headache, with or without aura trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.