Clinical trials
Mild Alzheimer Disease clinical trials
Below are recruiting mild alzheimer disease clinical trials, each written for real people, not researchers. We’re tracking 295 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05372172Recruiting
Tennessee Alzheimer’s study for people 60 and older
This study is looking at how brain and memory changes show up in people across the Alzheimer’s spectrum—from normal thinking to mild memory problems to Alzheimer’s disease. You might join if you can do study visits and an MRI and have a reliable study partner available.
Nashville, TennesseeAges 60 years+ - NCT07399171RecruitingPhase 2
Testing HT-4253 to prevent Alzheimer's in APOE4 carriers
This trial tests an experimental drug called HT-4253 to see if it can prevent Alzheimer's disease in people who are at higher genetic risk (carry the APOE4 gene) and have early signs of amyloid buildup in the brain. If you qualify, you would take the drug or a placebo and be monitored over time.
Abu Dhabi, Abu Dhabi EmirateAges 50–75 - NCT05405075Recruiting
Alzheimer’s research study with brain tests and blood samples
This study supports Alzheimer’s research by collecting health and thinking (cognitive) test results and blood samples to study genetics and biomarkers. You may be enrolled if you’re age 40 or older and can do these checkups, even if you have mild memory problems or dementia.
Phoenix, ArizonaAges 40 years+ - NCT05516667Recruiting
Study of Alzheimer’s patients and their families
This study follows people with Alzheimer’s disease and family members over 2 years. It uses regular questionnaires and medical checkups to better understand needs and health changes for patients and caregivers.
France, MarseilleAges 18 years+ - NCT06880406Recruiting
Study of cell energy in Alzheimer's and other dementias
This study looks at how energy production in cells (mitochondria) differs in people with Alzheimer's or other dementias compared to healthy volunteers. It involves a one-time spinal tap to collect fluid for analysis.
Nice, PACAAges 18 years+ - NCT07109999Recruiting
Biomarker study for Alzheimer's disease
This study uses brain scans or spinal fluid tests to confirm Alzheimer's-related changes. It aims to track the disease over time to better understand and improve care.
Beijing, Beijing MunicipalityAges 40 years+ - NCT03035851Recruiting
Exercise program for older adults at risk of memory decline
This trial tests whether a structured aerobic (heart-pumping) exercise program can improve memory and thinking in older adults who feel memory trouble but have not been diagnosed with dementia. It focuses on people who are “at increased risk” due to common health factors like high blood pressure or diabetes.
Calgary, AlbertaAges 50–80 - NCT07598617Recruiting
Testing a New Computer Memory Assessment for Early Cognitive Changes
This study evaluates a new computer-based test to detect early memory and thinking changes before they progress to dementia. Researchers are looking for adults 65+ who've noticed subtle cognitive changes in the last 5 years to help refine and test this assessment tool.
Plymouth, DevonAges 65 years+ - NCT07516119Recruiting
Predicting Alzheimer's Risk Before Memory Loss Occurs
This study identifies people at high risk for Alzheimer's disease before symptoms develop, using genetics and digital tools to track brain health over time. If you qualify, you'll help researchers understand who will develop cognitive decline and potentially enable earlier interventions.
San Diego, CaliforniaAges 55 years+ - NCT07272811Recruiting
Computer memory testing for early Alzheimer's signs
This study uses a computer-based platform to test memory and thinking in healthy adults and in people with mild memory concerns (called aMCI). The goal is to better understand how memory changes with age and to spot early signs of Alzheimer's disease.
Milan, ItalyAges 55–80 - NCT03702907Recruiting
Study of aging and a brain sample bank
This study follows adults as they age and may collect biological samples for future research. It could help researchers understand early and late changes related to aging and brain health.
Washington D.C., District of ColumbiaAges 45 years+ - NCT03761381Recruiting
Eye scan study for mild Alzheimer’s and memory changes
This study uses detailed eye imaging (an eye scan) to look for signs related to probable Alzheimer’s disease and mild dementia. It may help researchers understand whether eye scans can reflect brain changes and improve detection.
Portland, OregonAges 55 years+ - NCT05822362RecruitingPhase 2
CBD for People with Early Memory Trouble Risk
This Phase 2 study tests whether CBD (a cannabis-derived product) can improve thinking and memory in people who are at risk for Alzheimer’s disease. You would be followed for about 24 weeks with memory/thinking check-ins and require a study partner to help with certain assessments.
Aurora, ColoradoAges 55–85 - NCT06429124Recruiting
Time-restricted eating for mild cognitive impairment
This trial tests whether a time-restricted eating schedule (eating only during certain hours of the day) can help people with mild cognitive impairment (MCI) or early Alzheimer’s disease. It is a lifestyle study that can be done mostly from home with a computer or smartphone.
Phoenix, ArizonaAges 55–89 - NCT00585572Enrolling by invitation
Wisconsin Brain Donor Program for research after death
This program collects donated brain tissue and related samples after death to help researchers study brain diseases. You may be eligible if you’re an approved family member of a specific study participant, or you meet certain health and consent requirements.
Madison, WisconsinAges 18 years+ - NCT07602283Recruiting
Music to Help with Pain and Memory Problems
This study tests whether listening to music can help reduce pain and improve thinking in people with early memory loss or mild dementia. Researchers will monitor brain activity, heart rate, and pain levels while you or your loved one participate in music sessions.
New Haven, ConnecticutAges 50–80 - NCT07611396Recruiting
Study of brain changes in memory and thinking with aging
This study follows people with normal thinking, early memory problems, or Alzheimer's disease to understand how the brain changes over time. Researchers will use smell tests, blood work, and memory testing to learn more about these conditions and potentially help future treatments.
Germantown, MarylandAges 55 years+ - NCT07287852Enrolling by invitationPhase 2
Ginkgo biloba extract for mild cognitive impairment
This trial tests whether a specific ginkgo biloba extract (EGb761) can improve thinking and memory in people with mild cognitive impairment (MCI). It also looks at changes in blood markers related to the condition.
JerusalemAges 65 years+ - NCT07238049Enrolling by invitation
Real-world dementia outcomes: an observational study
This study follows people with memory or thinking problems over time to learn more about how these conditions progress. It's an observational study, meaning no new treatments are tested—just information is collected from your regular care.
BangorAges 45 years+ - NCT04240665Enrolling by invitation
Test a digital notebook for memory problems
This study tests a digital “memory notebook” to help people who have early memory concerns keep track and report changes over time. It may be useful if you’re having mild memory issues and can complete surveys with a study partner.
Sacramento, CaliforniaAges 60 years+ - NCT06094192Recruiting
Brain stimulation to improve memory in Alzheimer's
This study tests whether a gentle, noninvasive brain stimulation technique called tACS can help improve memory in people with Alzheimer's disease or mild cognitive impairment. It may also include healthy older adults for comparison.
Boston, MassachusettsAges 50–100 - NCT04124029Recruiting
Study how mild brain injuries may relate to dementia
This study looks at how past mild traumatic brain injury may contribute to brain changes seen in chronic traumatic encephalopathy (CTE) and Alzheimer’s disease (AD). It may help researchers understand risk and brain markers by comparing people with mild or moderate TBI, people with mild memory problems, and healthy controls.
Boston, MassachusettsAges 30–90 - NCT05934188Recruiting
Study how gut signals relate to brain aging and diseases
This study looks at how the gut may influence the brain in normal aging and conditions like Alzheimer’s, Parkinson’s, and multiple sclerosis. It may help researchers understand new ways to measure or treat these brain changes over time.
Venice-Lido, VeniceAges 20–90 - NCT07033494RecruitingPhase 2
Study of MK-2214 for early Alzheimer's disease
This trial tests an experimental medicine called MK-2214 for people with early Alzheimer's (mild cognitive impairment or mild dementia). The goal is to see if it can slow memory and thinking problems.
Irvine, CaliforniaAges 50–85
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Common questions
- Are there clinical trials for mild alzheimer disease?
- Yes. Clin2 currently lists 295 recruiting mild alzheimer disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mild alzheimer disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mild alzheimer disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.