Clinical trials
Mild Alzheimer Disease clinical trials
Below are recruiting mild alzheimer disease clinical trials, each written for real people, not researchers. We’re tracking 295 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05950607Recruiting
Nursing home study to reduce unnecessary antibiotic use
This study looks at ways to lower how often antibiotics are used in nursing home residents with Alzheimer’s disease and other dementias. It aims to make antibiotic use more appropriate while monitoring resident outcomes.
Boston, MassachusettsAges 60–106 - NCT06923007Recruiting
Vagus nerve stimulation for Alzheimer's disease
This trial tests if a nerve stimulation device can help people with mild to moderate Alzheimer's. It is for patients aged 50 to 80 who are on a stable medication.
BeijingAges 50–80 - NCT05016219Recruiting
Light therapy to improve sleep and thinking in early Alzheimer’s
This trial studies rhythmic light therapy to help people with early Alzheimer’s or mild memory problems, especially when sleep is getting worse. If you fit the sleep and vision/medical safety requirements, the study may see whether the therapy improves sleep and thinking-related symptoms.
Menands, New YorkAges 55 years+ - NCT06403345Recruiting
Green activity program for memory challenges
This study tests a green activity program for people with memory challenges. You and a friend or family member will take part in outdoor activities to see if they help with thinking and well-being.
Bloomington, IndianaAges 45 years+ - NCT04500847RecruitingPhase 1
Testing repurposed HIV-like drugs for early Alzheimer’s symptoms
This Phase 1 study tests whether an existing type of anti-viral medicine (nucleoside reverse transcriptase inhibitors) can help people with early Alzheimer’s disease. It also focuses on safety and proper dosing while measuring brain-related changes and memory-related symptoms.
Los Angeles, CaliforniaAges 50–85 - NCT04601038RecruitingPhase 2
Testing a stress-blocking drug for early Alzheimer's risk
This study tests a new medication, CORT108297, that may help protect the brain from the harmful effects of stress in people at risk for Alzheimer's disease. It is looking for adults age 55 and older who either have mild memory problems or are healthy but have a family history, APOE4 gene, or memory concerns.
Baltimore, MarylandAges 55 years+ - NCT05468905Recruiting
Study of aging and early thinking changes over time
This study follows adults 40+ to better understand and track changes in memory and thinking as people age. It groups people with normal thinking, subjective complaints, mild cognitive impairment, early Alzheimer’s, and vascular (blood vessel) related brain changes to find what predicts progression.
Hangzhou, ZhejiangAges 40–99 - NCT05710549Recruiting
Brain study of autobiographical memory using brain stimulation
This study looks at how the brain supports remembering your own past experiences. It tests brain mechanisms using brain scanning (MRI) and noninvasive brain stimulation to see how these memory processes work.
Geneva, Canton of GenevaAges 18–85 - NCT05877196Recruiting
Adaptive walking and fitness program for mild memory decline
This study tests an “adaptive” exercise plan that adjusts over time to help improve aerobic fitness and your body’s fitness response in people with mild memory problems or early Alzheimer’s. It may help you safely build the kind of fitness that supports brain health, while researchers monitor changes with fitness testing and blood work.
Phoenix, ArizonaAges 65 years+ - NCT05929703Recruiting
Care approach for hospitalized older adults at risk of confusion
This trial tests new ways to help hospitalized older adults (and their family/care partners) stay comfortable and avoid or reduce episodes of acute confusion. It focuses on people who are likely to develop delirium during their hospital stay.
Orange, CaliforniaAges 70 years+ - NCT06040905Recruiting
Coenzyme Q10 for cognitive decline with high blood sugar and muscle loss
This trial tests whether Coenzyme Q10 supplements help people with mild memory loss or Alzheimer's who also have high blood sugar and early muscle weakness. It aims to see if CoQ10 can improve thinking and daily function.
TaichungAges 50–80 - NCT06112860Recruiting
Over-the-counter hearing aids for memory loss study
This trial tests whether over-the-counter hearing aids can help people with mild memory loss (mild cognitive impairment or mild dementia) who also have hearing loss. You and a communication partner will participate together to see if improving hearing can also help with thinking and communication.
Evanston, IllinoisAges 60–90 - NCT06561906Recruiting
Early Alzheimer's detection using scans, genetics and blood
This study uses brain scans, blood tests, and genetic information to find early signs of Alzheimer's disease before memory problems start. It aims to predict who might develop Alzheimer's in the future.
Nanjing, JiangsuAges 50–79 - NCT07041450Recruiting
Screening for Alzheimer's treatment using digital tests and blood tests
This study is testing whether simple digital memory tests and blood tests can help find people who might qualify for anti-amyloid treatments (medications that target Alzheimer's-related proteins). It aims to make screening easier and faster, without needing a spinal tap or PET scan.
Greenfield Park, QuebecAges 55–90 - NCT07075770Recruiting
New magnetic and electrical brain stimulation for mild Alzheimer's
This trial tests a new, noninvasive treatment that combines magnetic and electrical stimulation to target a specific brain network in people with mild Alzheimer's disease. It aims to slow memory decline and improve brain function.
Rome, ItalyAges 50–85 - NCT06824142Recruiting
Testing a 3D clock for Alzheimer's time orientation
This study tests a 3D tool (like a special clock) to help people with Alzheimer's keep track of time. You may be eligible if you have mild to moderate Alzheimer's and trouble with time orientation.
ChampcueilAges 65 years+ - NCT05561205Recruiting
Brain stimulation to treat persistent apathy
This trial tests a noninvasive brain stimulation treatment (called rTMS) to help people who have had ongoing apathy (lack of motivation/interest) for at least a month. You might benefit if your apathy is persistent, your other symptoms are stable, and you meet the safety and medication rules.
Toronto, OntarioAges Any age - NCT07731191Recruiting
Digital tools to predict Alzheimer's risk factors
This study uses smartphone tools to track early signs of Alzheimer's by analyzing risk factors. It is for people with mild cognitive issues (MCI) or subjective cognitive decline (SCD) who do not have dementia.
Brescia, BSAges 18 years+ - NCT06129838Recruiting
Inflammation in Alzheimer's disease using a brain scan
This study uses a special PET scan to look for inflammation in the brains of people with Alzheimer's or related dementias. It may help researchers understand how inflammation affects memory and thinking problems.
St Louis, MissouriAges 50 years+ - NCT05591027RecruitingPhase 1
Testing Centella asiatica for memory problems in older adults
This Phase 1 study tests whether Centella asiatica (a plant-based supplement) is safe and reaches its intended target in people with mild cognitive impairment or early Alzheimer’s disease. It also checks how it affects memory-related brain measures like MRI scans, which is why multiple scans are required.
Portland, OregonAges 60–85 - NCT03174938Recruiting
BioFINDER 2 study for healthy aging and memory problems
This study uses brain scans and a spinal fluid test to better understand memory and thinking changes in different groups, from people with healthy thinking to early or established dementia. If you qualify, it may help researchers learn what’s driving these conditions and how they progress.
ÄngelholmAges 20–100 - NCT06080659Recruiting
Brain network study for Alzheimer's and Parkinson's
This study uses brain scans to look for patterns that might help diagnose memory or movement problems like Alzheimer's or Parkinson's disease. It compares people with mild symptoms, like forgetfulness or early Parkinson's, to healthy volunteers.
RennesAges 50–80 - NCT06335836Recruiting
Social connections and brain health in memory decline
This study looks at how being socially isolated or socially active affects memory and brain health in people who feel their thinking is getting worse. You may join if you notice a slow decline in memory or thinking, but otherwise have normal test results.
Nanjing, China, JiangsuAges 45–85 - NCT06962111Recruiting
Partner in Care Living Alone Plus study for early-stage dementia
This study tests a workshop to help people with early-stage memory problems who live alone. If you have mild dementia or mild cognitive impairment and can join Zoom sessions, you may be eligible.
Phoenix, ArizonaAges 60 years+
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Common questions
- Are there clinical trials for mild alzheimer disease?
- Yes. Clin2 currently lists 295 recruiting mild alzheimer disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mild alzheimer disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mild alzheimer disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.