Combining insulin and semaglutide for memory in MCI with metabolic syndrome
Treatments studied
Part of Brain & nervous system, Hormones & metabolism, Mental health clinical trials.
This study tests if a combination of insulin and semaglutide (a diabetes drug) can improve memory and thinking in people with mild cognitive impairment (MCI) who also have metabolic syndrome (a cluster of health issues like large waist, high blood sugar, and high blood pressure). It aims to see if treating blood sugar problems helps protect the brain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with mild cognitive impairment (MCI) based on specific memory tests.
- You have metabolic syndrome, which means a large waist, high blood sugar, and either abnormal cholesterol or high blood pressure.
- You can speak and understand Hebrew fluently.
- You have a friend or family member who can act as a study partner and come to visits with you.
- You do not have diabetes (type 1 or type 2).
- You are not taking medications like corticosteroids or Ozempic that affect blood sugar.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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