Clinical trials
Mild Cognitive Disorder clinical trials
Below are recruiting mild cognitive disorder clinical trials, each written for real people, not researchers. We’re tracking 312 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06089096Recruiting
Sleep apnea and memory in people with mild memory problems
This study looks at whether sleep apnea (pauses in breathing during sleep) is linked to thinking and memory in people who have mild memory problems. You will do a home sleep test and take memory tests to help researchers find this connection.
Hong KongAges 18 years+ - NCT07237009Recruiting
Personalized reminiscence therapy for memory loss
This trial tests a digital app that uses personal photos and memories to help people with early memory problems feel less depressed or apathetic. It's designed for seniors who have mild cognitive impairment or early dementia.
AngersAges 60 years+ - NCT07220694Recruiting
Sabroxy supplement for memory and insulin resistance
This study tests whether a supplement called Sabroxy can improve insulin resistance and memory in adults with mild cognitive impairment and insulin resistance. It may help if you have early memory problems and your blood sugar is slightly higher than normal.
San Francisco, CaliforniaAges 40–80 - NCT06598163Recruiting
Cognitive training app for mild memory problems
This trial tests a mobile app called Five Lives MED to see if it can improve thinking and memory in people with mild cognitive impairment (MCI). You can join if you have MCI and are 50 or older.
Paris, Île-de-France RegionAges 50 years+ - NCT07182396Recruiting
Video games vs ball tossing for hand-eye coordination in older adults
This study tests whether playing video games or tossing balls can improve hand-eye coordination in older adults with mild memory problems. It is designed for people 60 and older who have mild cognitive impairment but are otherwise independent.
IslamabadAges 60 years+ - NCT07027072RecruitingPhase 2
Testing KDS2010 for early Alzheimer's memory loss
This study tests a new drug called KDS2010 for people with early Alzheimer's or mild memory loss. It aims to see if the drug can slow thinking and memory decline. You will need a caregiver to help with visits and must have a special brain scan showing amyloid plaques.
Gwangju, GwangjuAges 50–85 - NCT03851523Recruiting
Tracking memory changes in people with early Alzheimer’s symptoms
This study follows people over time to better understand how memory and thinking complaints progress in early Alzheimer’s disease (from “subjective cognitive decline” to mild cognitive problems). It may help researchers understand who is likely to decline and how symptoms change, which could support future treatments.
Barcelona, CataloniaAges 45 years+ - NCT06897670Recruiting
Brain blood flow patterns in mood and memory disorders
This study uses a headband with light sensors (fNIRS) to measure blood flow in the brain while you do thinking tasks. It aims to understand differences in brain activity for people with depression, bipolar disorder, or mild memory loss.
Rochester, MinnesotaAges 18 years+ - NCT06330844Recruiting
Stress & memory support for Black and Hispanic older adults
This research study tests a new program that combines help for stress caused by racism with memory training for people with mild cognitive impairment. It may help Black and Hispanic/Latine older adults find ways to cope and improve thinking skills.
Chicago, IllinoisAges 65 years+ - NCT06780917Recruiting
Online cognitive testing for older adults with depression or memory concerns
This study tests whether an online cognitive assessment platform (Creyos) is valid for older adults with major depression or mild cognitive impairment. Participants will complete brain games or puzzles to see how well the online tool measures thinking skills.
Toronto, OntarioAges 60 years+ - NCT06601933RecruitingPhase 2
Computer thinking exercises for memory concerns in older adults
This study tests whether a computer-based thinking exercise program can improve memory and brain function in older adults with mild memory concerns. If you have age-related memory changes but not dementia, you may be able to join and get a free MRI scan.
Miami, FloridaAges 55–89 - NCT06584357Recruiting
Digital and blood markers linked to brain scans in older adults
This study is looking for older adults (60–90) who are either cognitively normal, have mild cognitive impairment (MCI), or have mild-to-moderate Alzheimer's dementia. It aims to see how digital tests and blood-based markers relate to brain scans (amyloid and tau PET). You will need a study partner, undergo MRI and PET scans, and give blood samples.
Atlantis, FloridaAges 60–90 - NCT04754906Recruiting
Study how thinking abilities affect planning movement
This study looks at how well people can plan and control movements, and whether thinking ability affects that process. It compares healthy younger adults, healthy older adults, and older adults with mild cognitive problems.
DijonAges 18 years+ - NCT05245903Recruiting
Test a supplement and track brain changes with wearable sensors
This study tests whether taking nicotinamide riboside (a form of niacin) affects early memory changes in people with mild cognitive impairment (MCI) or mild Alzheimer’s disease (AD). It also uses passive wearable or sensor data (“digital biomarkers”) to measure changes over time.
Belmont, MassachusettsAges 18–89 - NCT05948930Recruiting
Exercise and brain training for mild memory problems
This study tests whether a mix of physical exercise and computer brain training can improve working memory in people with mild cognitive impairment (MCI). It may help by strengthening memory skills and supporting brain health through supervised activity and computer-based practice.
Baltimore, MarylandAges 50–80 - NCT05790707Recruiting
Ablation for persistent atrial fibrillation to help memory
This study checks whether a procedure called atrial fibrillation ablation can slow memory problems in people who already have mild cognitive impairment. Participants will be tested on thinking and memory before and after treatment to see if the procedure helps.
AngersAges 60–80 - NCT05446584RecruitingPhase 2
Study memory changes in people with past mild head injury
This Phase 2 study looks at how memory problems (amnestic mild cognitive impairment) may relate to a history of a mild traumatic brain injury. It compares people with a past mild head injury to people without one to better understand what might be driving memory symptoms.
Dallas, TexasAges 55 years+ - NCT05273125Recruiting
Testing mobility and thinking in people with mild cognitive problems
This study looks at how well people with mild cognitive problems can think and move, using brief learning/thinking tests and a walking task. It may help researchers understand changes early enough to guide future care.
LilleAges 65 years+ - NCT05201534Recruiting
Math and thinking skills training for school-age children
This trial studies interventions to improve math and cognitive (thinking) skills in elementary school children. It includes both children with math learning difficulties and typically developing children, using tests and MRI brain scans for those who can participate.
Palo Alto, CaliforniaAges 6–12 - NCT02740634Recruiting
Brain imaging study for Alzheimer's disease
This study uses brain scans to understand Alzheimer's disease and related conditions that affect memory, language, or vision. It looks at how changes in the brain happen over time in people with these diagnoses.
Rochester, MinnesotaAges 21–80 - NCT06705738Recruiting
Mediterranean diet and olive compound for mild memory loss
This study tests whether a Mediterranean diet combined with a natural compound found in extra virgin olive oil (oleocanthal) can help people with mild memory problems (mild cognitive impairment). It aims to see if this combination can slow down or improve memory decline.
Thessaloniki, ThessalonikiAges 60–85 - NCT07799584Recruiting
Brain stimulation with tai chi for mild memory problems
This study tests a new type of non-invasive brain stimulation combined with tai chi to see if it can improve memory and thinking in older adults with mild cognitive impairment (MCI), a stage between normal aging and dementia. It may help slow down memory decline and improve daily function.
Shanghai, Shanghai MunicipalityAges 60–80 - NCT07757542RecruitingPhase 2
Hydrogen gas for mild cognitive impairment
This trial tests whether breathing in a small amount of hydrogen gas is safe and might help people with mild cognitive impairment. It aims to see if this simple approach could support brain health.
Ostrava, Moravian-Silesian RegionAges 50–80 - NCT07558785Enrolling by invitation
Testing speech and memory checks at home for early thinking problems
This study uses a video-based system at home to check your speech and memory, helping doctors spot thinking problems early using artificial intelligence. The goal is to see if this simple, at-home test can reliably catch early memory and thinking changes.
PilsenAges 40 years+
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Common questions
- Are there clinical trials for mild cognitive disorder?
- Yes. Clin2 currently lists 312 recruiting mild cognitive disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mild cognitive disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mild cognitive disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Mild Cognitive Impairment
- Amnestic Mild Cognitive Impairment
- Cognitive Dysfunction, Cognitive Disorder
- Mild Cognitive Impairment (MCI) Amnestic
- Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
- Amnestic Mild Cognitive Disorder
- Mild Cognitive Impairment Due to Alzheimer's Disease
- Cognitive Impairment
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.