Clinical trials
Mild Cognitive Impairment clinical trials
Below are recruiting mild cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 406 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06027554RecruitingPhase 2
MitoQ for frailty, walking, memory, and blood flow in older adults
This trial tests whether a supplement called MitoQ can improve blood vessel health, walking speed, and thinking skills in older adults who are frail or have mild memory problems. It aims to see if MitoQ helps maintain independence and quality of life.
Farmington, ConnecticutAges 65–80 - NCT06408103Recruiting
Brain health program for you and your caregiver
This study tests a program that combines exercise, nutrition, and mental activities for both you and your family caregiver. It aims to help keep your thinking and memory skills strong.
Bucaramanga, Santander DepartmentAges 55 years+ - NCT06753578Recruiting
Cognitive training for seniors with mild memory loss
This trial tests a new cognitive training program designed to improve quality of life and thinking skills in older adults living in care facilities who have mild cognitive impairment (MCI). The program uses acceptance and commitment therapy (ACT) to help participants adapt to memory challenges.
Santander, CantabriaAges 65 years+ - NCT07039708Recruiting
Computer memory training for older adults
This trial tests a computer-based training program to help improve memory in older adults, whether they are healthy, have memory complaints, or have mild cognitive impairment. It aims to find strategies that might keep your mind sharp as you age.
Hong Kong, Hong KongAges 65 years+ - NCT07383311Recruiting
Memory, sleep, and a natural supplement
This trial tests whether a natural substance (from wheat germ) that boosts a process called autophagy can help improve sleep in people who are worried about their memory or have mild memory problems but do not have dementia.
Greifswald, Mecklenburg-VorpommernAges 55–70 - NCT07667478Recruiting
Brain stimulation study for early Alzheimer's memory loss
This study tests whether a non-invasive magnetic brain stimulation technique can help improve memory in people with early Alzheimer's disease. It may be an option if you have mild cognitive impairment or mild dementia due to Alzheimer's and have had a positive blood test for Alzheimer's markers.
Houston, TexasAges 55–90 - NCT06826157Enrolling by invitation
Brain Wave Patterns in Early Memory Loss and Dementia
This study uses an advanced EEG (electroencephalogram) to measure brain wave activity in people with early Alzheimer's, frontotemporal dementia, or Lewy body dementia. It aims to find patterns that could help doctors better understand the disease and predict how it might progress.
Milan, ItalyAges 50–85 - NCT06686563Enrolling by invitation
Sights & sounds for better health in older adults
This trial studies whether using light and sound patterns can improve thinking, mood, and physical health in older adults. It aims to find a simple, non-drug way to boost well-being.
Gandra, ParedesAges 18–100 - NCT06407141Enrolling by invitation
Brain stimulation study for older adults with mild memory loss
This trial tests whether a harmless brain stimulation technique called TPS can improve memory and thinking in older adults with mild memory problems. You may be able to join if you have MCI, are right-handed, and are generally healthy otherwise.
Hong KongAges 50–100 - NCT07220798Recruiting
A program to support caregivers of people with heart failure and memory problems
This study tests a program to help caregivers of people with heart failure and memory problems take better care of themselves, so they can feel better and support their loved one more effectively.
New York, New YorkAges 18–101 - NCT06246929Recruiting
Healthy aging for Black adults with chronic pain and memory concerns
This study tests a program to help Black adults aged 50+ manage chronic pain and early memory changes. It compares two approaches to see which works better for improving daily life and thinking skills.
Boston, MassachusettsAges 50 years+ - NCT07497334Recruiting
Combined therapy for older adults with mild thinking and mobility issues
This study tests a program that combines mental exercises, physical training, and brain stimulation to help older adults with mild thinking and mobility problems stay independent. It aims to improve walking, memory, and daily function.
Hong KongAges 60–90 - NCT04124029Recruiting
Study how mild brain injuries may relate to dementia
This study looks at how past mild traumatic brain injury may contribute to brain changes seen in chronic traumatic encephalopathy (CTE) and Alzheimer’s disease (AD). It may help researchers understand risk and brain markers by comparing people with mild or moderate TBI, people with mild memory problems, and healthy controls.
Boston, MassachusettsAges 30–90 - NCT07764679RecruitingPhase 3
Brain scan to detect Alzheimer's plaques
This study tests a new PET brain scan that uses a special dye to show amyloid plaques, which are linked to Alzheimer's disease. It may help doctors see if your memory problems are caused by Alzheimer's or something else.
Beijing, Beijing MunicipalityAges 40 years+ - NCT07287852Enrolling by invitationPhase 2
Ginkgo biloba extract for mild cognitive impairment
This trial tests whether a specific ginkgo biloba extract (EGb761) can improve thinking and memory in people with mild cognitive impairment (MCI). It also looks at changes in blood markers related to the condition.
JerusalemAges 65 years+ - NCT06639282RecruitingPhase 2
Testing siponimod for mild Alzheimer's dementia
This study tests if a medicine called siponimod, already used for multiple sclerosis, can help people with mild Alzheimer's dementia. You will take a pill daily and be monitored closely for safety and cognitive changes.
Phoenix, ArizonaAges 50–85 - NCT07208019Recruiting
Electroacupuncture for memory and thinking after stroke
This study tests whether electroacupuncture (using tiny electric pulses through thin needles) can help improve memory, focus, and thinking after a stroke. If you have mild to moderate thinking problems after a stroke, this treatment may help support your recovery.
Hangzhou, ZhejiangAges 35–80 - NCT05655325Recruiting
Exercise program to improve thinking in older adults with mild memory trouble
This study tests whether a supervised exercise plan can improve executive thinking (like planning and task control) in older adults with mild cognitive impairment. Researchers also look for brain changes using an MRI.
New York, New YorkAges 55 years+ - NCT06547099Recruiting
Understanding new blood markers in memory loss and dementia
This study is looking for older adults (60+) to help researchers better understand how to detect and track memory changes and dementia. Participants will provide blood samples and other health information over time to identify new markers that might help with early diagnosis.
St Louis, MissouriAges 60 years+ - NCT05448768Enrolling by invitation
Testing brain stimulation in people with mild memory problems
This study tests a brain stimulation approach (TBS) to see if it can improve thinking and memory in people with mild cognitive impairment. It may also explore why it works by looking at brain-related measurements after TBS.
TaoyuanAges 50–90 - NCT07657624Recruiting
Heart disease and memory problems risk study
This study looks at what factors might increase the risk of memory and thinking problems in people with coronary heart disease. It includes testing your memory and metabolism during a hospital stay.
Beijing, ChinaAges 18 years+ - NCT05795634Recruiting
Study stress effects in people at risk for Alzheimer’s
This study looks at how stress may affect thinking and memory in people with mild cognitive impairment (MCI) who are at risk for Alzheimer’s disease. You may be asked to do thinking tests and also involve a knowledgeable person who can report on changes over time.
Baltimore, MarylandAges 60 years+ - NCT07298876Enrolling by invitation
Ultrasound for memory and sleep in early Alzheimer's
This study tests if a gentle ultrasound treatment to the brain can help improve memory and sleep quality in people with very early Alzheimer's disease. If you have mild memory issues and trouble sleeping, this low-intensity approach might be a safe option to explore.
Hong Kong, Tai Po DistrictAges 60–85 - NCT05282550RecruitingPhase 2
Trazodone trial to improve sleep in early Alzheimer’s
This study tests whether the sleep medicine trazodone can improve thinking and memory in people with early Alzheimer’s-related changes who also have sleep problems. If better sleep helps the brain, it may improve memory test results over time.
Baltimore, MarylandAges 55 years+
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Common questions
- Are there clinical trials for mild cognitive impairment?
- Yes. Clin2 currently lists 406 recruiting mild cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mild cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mild cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Amnestic Mild Cognitive Impairment
- Mild Cognitive Impairment (MCI) Amnestic
- Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
- Mild Cognitive Impairment Due to Alzheimer's Disease
- Cognitive Impairment
- Subjective Cognitive Impairment
- Post-Stroke Cognitive Impairment (PSCI)
- Vascular Cognitive Impairment
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.