Clinical trials
Mild Cognitive Impairment clinical trials
Below are recruiting mild cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 406 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07558785Enrolling by invitation
Testing speech and memory checks at home for early thinking problems
This study uses a video-based system at home to check your speech and memory, helping doctors spot thinking problems early using artificial intelligence. The goal is to see if this simple, at-home test can reliably catch early memory and thinking changes.
PilsenAges 40 years+ - NCT07519798Enrolling by invitation
Brain Stimulation for Memory Problems in Older Adults
This study tests a new, non-invasive brain stimulation technique called transcranial temporal interference stimulation to see if it can improve memory and thinking skills in older adults with mild cognitive impairment (early memory loss that isn't yet dementia). Participants will receive the stimulation treatment and have their cognitive function monitored over time.
Shanghai, Shanghai MunicipalityAges 60–80 - NCT07474038Enrolling by invitation
AI-Supported Memory Training for Older Adults
This study tests a computer-based program that uses artificial intelligence (AI) to help older adults with mild memory problems improve their thinking skills. It is done remotely, so you can participate from home.
Pasadena, CaliforniaAges 65 years+ - NCT07332624Enrolling by invitation
Therapy via text for mild memory problems and mood changes
This study tests if acceptance and commitment therapy (ACT) delivered through instant messaging can help older adults with mild memory issues manage emotional or behavioral symptoms like anxiety, depression, or agitation.
Hong KongAges 50 years+ - NCT06973018Enrolling by invitation
Online cognitive rehab for mild memory problems
This trial tests an online program to help people with mild to moderate cognitive problems after a brain injury or nervous system disease improve their thinking skills. It is for Swedish speakers with internet access.
Stockholm, Stockholm CountyAges 18 years+ - NCT06809725Enrolling by invitation
Study of a headband device for cognitive health check
This study tests a new way to check cognitive (thinking and memory) health using a simple headband that measures electrical signals on your scalp. It is looking for people 65 to 90 years old, with or without memory concerns, and a family member or friend who can also take part.
Miami, FloridaAges 65–90 - NCT06723015Enrolling by invitationPhase 2
Tau PET in anti-amyloid therapy for Alzheimer's
This study uses brain scans to see how anti-amyloid treatments affect tau protein buildup in people with early Alzheimer's. If you have mild cognitive impairment or mild Alzheimer's, you may be eligible to help understand how these treatments work.
Rochester, MinnesotaAges 50–90 - NCT06682741Enrolling by invitation
Comparing exercise programs for brain health in women
This study tests whether different types of exercise training can improve thinking and memory in women. It may help find the best workout for keeping your mind sharp.
Poznan, PolandAges 50 years+ - NCT06434168Enrolling by invitation
Yoga for brain health in heart failure
This study tests whether yoga can help improve memory and thinking for people with heart failure who also have mild memory problems. It aims to see if a gentle yoga program can support both heart and brain health.
Auburn, AlabamaAges 55–70 - NCT06379594Enrolling by invitation
Remote brain health clinic for mild memory problems
This study tests a remote 'brain health clinic' for people with mild memory or thinking problems (mild cognitive impairment). It aims to help diagnose the cause of memory issues from home, so you don't need to travel to a clinic.
London, Denmark HillAges 18 years+ - NCT06245031Enrolling by invitation
Long-term follow-up of sensory stimulation for Alzheimer's
This is a follow-up study for people who already completed the 12-month Hope Study (CA-0011). It tests long-term safety and effects of a gentle sensory stimulation device (light and sound) for Alzheimer's disease. You will continue using the device at home with a study partner.
Phoenix, ArizonaAges 50–92 - NCT06029114Enrolling by invitation
Brain scan study for memory problems
This study uses a special MRI to look at brain stiffness in people with normal memory, mild memory problems, or Alzheimer's disease. The goal is to see if this scan can help tell the difference between these groups.
Rochester, MinnesotaAges 18–100 - NCT06017505Enrolling by invitation
Using eSAGE for early detection of cognitive decline
This study uses a simple computer-based self-assessment (eSAGE) to detect early signs of memory or thinking problems. It may help identify cognitive impairment sooner and track changes over time.
Columbus, OhioAges 50 years+ - NCT05770479Enrolling by invitation
Testing long-lasting cognitive training for older veterans
This study looks at whether a cognitive training program you’ve already completed can keep helping over time, and whether it can be improved with “booster” sessions. It may help older veterans maintain thinking and daily functioning skills after earlier training.
San Diego, CaliforniaAges 55 years+ - NCT04701177Enrolling by invitation
Smartphone-based study of brain biomarkers in memory clinic patients
This observational study follows people with (or at risk for) Alzheimer’s-related brain changes and a comparison group without them. It uses clinic visits, cognitive testing, questionnaires, and possibly a spinal fluid test to better understand brain biomarkers and how they relate to thinking and daily life.
Corfu, CorfuAges 45 years+ - NCT04240665Enrolling by invitation
Test a digital notebook for memory problems
This study tests a digital “memory notebook” to help people who have early memory concerns keep track and report changes over time. It may be useful if you’re having mild memory issues and can complete surveys with a study partner.
Sacramento, CaliforniaAges 60 years+ - NCT03372317Recruiting
Tau brain PET imaging study for adults ages 55–90
This study uses a brain scan called PET to look at tau (a brain protein) and how it relates to thinking and memory. It may help researchers understand early brain changes, though it’s mainly for healthy people living near Columbia who have had an amyloid PET scan before.
New York, New YorkAges 55–90 - NCT03836950RecruitingPhase 1/Phase 2
Brain stimulation to improve thinking in Parkinson’s
This trial studies a noninvasive treatment called rTMS to help improve thinking and memory in people with Parkinson’s who have mild cognitive problems. It may help strengthen brain function, but it also has strict safety and eligibility rules to protect against seizure and metal-related risks.
Chicago, IllinoisAges 50 years+ - NCT04114994Recruiting
Memory testing study for adults 50 and older
This study checks how people’s thinking and memory change over time using a specific cognitive test. It may help researchers understand patterns of memory change and supports future research on brain health.
Miami, FloridaAges 50 years+ - NCT07041450Recruiting
Screening for Alzheimer's treatment using digital tests and blood tests
This study is testing whether simple digital memory tests and blood tests can help find people who might qualify for anti-amyloid treatments (medications that target Alzheimer's-related proteins). It aims to make screening easier and faster, without needing a spinal tap or PET scan.
Greenfield Park, QuebecAges 55–90 - NCT07135336Recruiting
Cognitive decline after surgery in older adults with memory problems
This study looks at how surgery and anesthesia affect memory and thinking in older adults who already have mild memory problems. It compares patients having elective non-cardiac surgery with a similar group who are not having surgery, to see if the surgery itself causes more confusion or memory decline.
Shenzhen, GuangdongAges 60 years+ - NCT07578896Recruiting
Balance Board Training for Children with Cognitive and Motor Delays
This study tests whether practicing on a special wobbling balance board can help improve how children with cognitive delays move and coordinate their bodies. The goal is to see if this type of training strengthens balance, coordination, and motor skills.
Lahore, Punjab ProvinceAges 6–10 - NCT05460143Recruiting
Optical brain scanning to study memory and thinking
This study uses brain “optical” and possibly MRI scans to understand how thinking and memory work in people with Lewy body dementia, Alzheimer’s disease, or mild memory problems. It may help researchers find better ways to measure brain changes and cognition over time.
CambridgeAges 18 years+ - NCT05785156Recruiting
Quick test study to predict stroke and memory disease outlook
This study tests quick new methods to measure “slowed actions” in people with stroke or memory-related brain conditions. The goal is to see whether these quick tests can help predict future outcomes and guide care.
AmiensAges 40–85
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Common questions
- Are there clinical trials for mild cognitive impairment?
- Yes. Clin2 currently lists 406 recruiting mild cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mild cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mild cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Amnestic Mild Cognitive Impairment
- Mild Cognitive Impairment (MCI) Amnestic
- Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
- Mild Cognitive Impairment Due to Alzheimer's Disease
- Cognitive Impairment
- Subjective Cognitive Impairment
- Post-Stroke Cognitive Impairment (PSCI)
- Vascular Cognitive Impairment
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.