Clinical trials
Mood clinical trials
Below are recruiting mood clinical trials, each written for real people, not researchers. We’re tracking 146 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05669703Recruiting
Tracking mood and activity patterns in bipolar disorder families
This study watches how a person’s mood and movement change over time, and how those patterns relate to bipolar disorder. It may help researchers better understand the condition in families and potentially improve future care.
Bethesda, MarylandAges 8–70 - NCT04870255Recruiting
Brain stimulation for depression in borderline personality disorder
This study tests a type of brain stimulation called rTMS to see if it can help improve mood in people who have both depression and borderline personality disorder. It may offer a new treatment option for those who haven't tried TMS before.
Stanford, CaliforniaAges 18–80 - NCT06481631Recruiting
Building trust between mothers and doctors after high-risk pregnancy
This trial studies ways to build trust between new mothers and healthcare providers after a high-risk pregnancy. It focuses on helping mothers in five rural Mississippi counties get better postpartum care.
Jackson, MississippiAges 18–45 - NCT06336590Recruiting
Does changing exercise time improve sleep in college students?
This study looks at whether changing the time you exercise (from evening to morning) can help college students sleep better. You'll wear a small wrist monitor to track your sleep and activity, and either keep your usual evening exercise routine or switch to morning exercise for 4 weeks.
New Brunswick, New JerseyAges 18–23 - NCT07006324Recruiting
Home visits for high-risk postpartum parents in Mississippi Delta
This program offers home visits after childbirth for mothers and parents in the Mississippi Delta who had a high-risk pregnancy. It aims to provide support and care to help you and your baby stay healthy.
Jackson, MississippiAges 18–45 - NCT06678880Recruiting
Sleep and light for mood during menopause
This study tests a program that combines better sleep habits with timed bright light exposure to help improve mood in women going through menopause. It may help reduce the sad or hopeless feelings that often come with this transition.
San Diego, CaliforniaAges 45–75 - NCT05616819Recruiting
Morning light program to improve mood in some service members
This study tests whether getting morning light exposure can improve mood for service members who currently have mild or more depression symptoms. You’d follow a plan for morning light over about 6 weeks, and the researchers check changes in mood.
Tucson, ArizonaAges 18–60 - NCT05058872RecruitingPhase 4
Study links birth-control hormones to brain reward responses
This Phase 4 study uses brain imaging and daily questions to understand how contraceptive hormones may affect reward and brain signals. You may be able to join if you meet the health, birth-control, and safety requirements for MRI.
Aurora, ColoradoAges 18 years+ - NCT05232383Recruiting
Testing how light at night affects sleep, alertness, and mood
This study looks at how exposure to artificial light changes sleep, daytime alertness, thinking skills, mood, and the body’s daily (circadian) rhythm. You may be asked to follow a strict sleep schedule and avoid certain substances so researchers can measure changes.
StrasbourgAges 18–40 - NCT05528926Recruiting
Resist irritability: a trial for children with ongoing behavior issues
This trial tests a program meant to reduce long-lasting irritability in children and teens who have conditions like ADHD, oppositional behavior, disruptive behavior, mood/anxiety problems, or DMDD. It includes children whose parents rate irritability as at least moderately severe and who have had symptoms for 6 months or more.
MontpellierAges 6–15 - NCT06716554Recruiting
Shatavari for menopausal symptoms in women
This study tests whether a natural herb called Shatavari can help with menopausal symptoms like hot flashes, sleep problems, and mood changes. It compares Shatavari to a placebo (a pill with no active ingredient) to see if it is safe and effective.
San Francisco, CaliforniaAges 45–55 - NCT07020572Recruiting
Teen mood support program (iMATTER) in primary care
This study tests a group program to help teenagers with mild to moderate depression symptoms feel better. It takes place in primary care and uses a phone, computer, or tablet for activities.
Philadelphia, PennsylvaniaAges 13–17 - NCT07548723Enrolling by invitation
Nerve Stimulation Device Reliability Study
This study tests how reliably a small ear-stimulation device measures heart-rhythm patterns. Researchers want to see if the device gives consistent readings across multiple measurement sessions, which could help doctors monitor heart health in the future.
SinopAges 18–40 - NCT07229014Recruiting
Collagen supplement for quality of life and appetite
This trial tests whether a daily collagen supplement can improve quality of life, appetite, and blood sugar control in overweight adults who feel low energy or have trouble sleeping. You will take the supplement, use a continuous glucose monitor, and complete online surveys.
London, LondonAges 18–65 - NCT06716034Recruiting
Mood and diet pilot trial for teens with depression
This study tests whether a special diet can help improve mood in teens with depression. You and your parent will work together online with the study team.
Toronto, OntarioAges 11–17 - NCT07689526Recruiting
BabaCare: Testing a Care Copilot
This study tests a smartphone app called Baba that helps people who live alone and feel exhausted. It aims to see if the app can make daily life easier and reduce feelings of burnout.
Baltimore, MarylandAges 65 years+ - NCT07482930Recruiting
Nerve stimulation and breathing test study in healthy adults
This study tests if a gentle nerve stimulation device placed on the ear can change how you breathe during a lung function test. It is only for healthy volunteers aged 18–40 who have no heart, lung, nerve, or mental health conditions.
SinopAges 18–40 - NCT07407777Recruiting
Can a daily drink improve your gut health and mood?
This trial tests a powder made from mushrooms and algae that you mix into a drink once a day for 30 days. Researchers want to see if it helps with minor tummy troubles and how you feel emotionally.
San Francisco, CaliforniaAges 18 years+ - NCT07599930Recruiting
Novel Snack for Perimenopausal Symptoms and Wellness
This study tests whether a specially designed snack can help reduce hot flashes, night sweats, mood changes, and other symptoms that happen during perimenopause (the years leading up to menopause). You'll eat the snack regularly and answer questions about how you feel.
London, LondonAges 40–55 - NCT07287605Recruiting
Virtual reality for mood during focused ultrasound for essential tremor
This study tests if using virtual reality can improve your mood while you undergo a focused ultrasound procedure for essential tremor. If you are already scheduled for this treatment, you may be able to join.
North York, OntarioAges 18 years+ - NCT06505980Recruiting
Parent training for child behavior concerns
This trial tests a brief telehealth program to help parents manage their child's challenging behaviors. It may help if your child has elevated behavior issues and you can participate online.
Aurora, ColoradoAges 3–5 - NCT07252011Recruiting
Brain stimulation study for mood swings
This study tests a non-invasive electrical stimulation method to help people with mood swings. It aims to improve mood stability and brain function.
Pittsburgh, PennsylvaniaAges 18–65 - NCT06020261Recruiting
Parent training for kids with irritability
This study tests if a parent management training program can help reduce irritability in children. You and your child will work together with a therapist to learn new ways to handle challenging behaviors.
Aurora, ColoradoAges 10–14 - NCT07220447RecruitingEarly Phase 1
L-Theanine for relaxation and mood in cancer survivors
This trial tests whether a natural supplement called L-theanine, found in green tea, can help cancer survivors feel more relaxed and improve their mood. You may qualify if you have finished cancer treatment, have been in surveillance for at least 6 months, and feel anxious.
Duarte, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for mood?
- Yes. Clin2 currently lists 146 recruiting mood studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mood trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mood trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.