Clinical trials
Multiple sclerosis clinical trials
A condition in which the immune system attacks the protective covering of nerves. We’re tracking 428 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07380295Recruiting
Helping people with MS stay at work and feel better
This study tests a program to help people with multiple sclerosis (MS) stay active at work and improve their well-being. It is for adults aged 18 to 65 who have been referred for a neuropsychological assessment at Gävle Hospital.
GävleAges 18–65 - NCT07376772Recruiting
Wearable vibration therapy for arm and hand function in multiple sclerosis
This study tests if a wearable device that gently vibrates the arm can improve hand and arm function in people with multiple sclerosis. You would use the device at home while doing daily activities.
Gainesville, FloridaAges 18–100 - NCT07321093RecruitingPhase 3
A study of BCD-281 for relapsing-remitting MS
This trial tests a new medicine called BCD-281 for people with relapsing-remitting multiple sclerosis (RRMS). It aims to see if the drug can reduce relapses and improve disease control.
Nizhny NovgorodAges 18–55 - NCT02433028Recruiting
Long-term study for MS and related nervous system conditions
This is a long-term hospital study that follows people diagnosed with MS (and a few related conditions) to understand how disease changes over time. You may be asked to have regular check-ups, brain scans, and provide blood samples so researchers can track disease and treatment effects.
Aarau, Canton of AargauAges Any age - NCT07189325RecruitingPhase 3
Comparing two ways to manage relapsing-remitting MS
This trial tests if it's safe to stop or reduce anti-CD20 treatment after several years of stable disease, compared to continuing it. It's for people with relapsing-remitting MS who are at least 40 years old and have had no MS activity for the past 3 years on anti-CD20 therapy.
MontpellierAges 40 years+ - NCT05982925Recruiting
Brain imaging study in multiple sclerosis
This study uses MRI scans to look at how multiple sclerosis affects the outer layer of the brain over time. It aims to learn more about the disease to help improve future treatments.
New York, New YorkAges 18 years+ - NCT03109288RecruitingPhase 1/Phase 2
Biomarker-guided combination treatment for residual multiple sclerosis activity
This early-phase study tests combination treatments for multiple sclerosis (MS) based on lab “biomarkers” found in the spinal fluid. It aims to reduce ongoing MS activity and help determine which treatment combinations may work best for different people.
Bethesda, MarylandAges 18–120 - NCT06501950Recruiting
Measuring silent MS progression with advanced tests
This study is looking for people with MS who are already on a monoclonal antibody therapy. It aims to measure subtle signs of disease progression using advanced tests, even if you feel stable.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT07636876Enrolling by invitation
Italian MS and Related Disorders Patient Registry
This is a registry study that collects health information from people with multiple sclerosis and related conditions. By joining, you help researchers better understand these diseases and improve future treatments.
Genova, GenovaAges Any age - NCT05500963Recruiting
TENS to reduce fatigue in relapsing-remitting multiple sclerosis
This study tests whether TENS, a non-drug device that delivers mild electrical signals through the skin, can reduce fatigue in people with relapsing-remitting multiple sclerosis (MS). It also includes an exercise-training portion and checks safety and comfort during the program.
Boulder, ColoradoAges 18–65 - NCT07517185RecruitingPhase 2
Early aggressive treatment for relapsing multiple sclerosis
This trial tests whether treating relapsing multiple sclerosis (RRMS) aggressively and early with a specific medication can slow disease progression. You may qualify if you were recently diagnosed, have had recent disease activity, and are willing to take a strong immunosuppressive drug with regular MRI monitoring.
FalunAges 18–50 - NCT06608797Recruiting
Computer-based cognitive training for multiple sclerosis patients
This study tests whether a computer-based cognitive training program is helpful and practical for people with multiple sclerosis who live in the community. It focuses on those who have some memory or learning difficulties.
East Hanover, New JerseyAges 19–65 - NCT07256704Recruiting
Hypnosis and attention for neurological conditions
This study looks at whether hypnosis can help improve attention in people with conditions like stroke, traumatic brain injury, or multiple sclerosis. It may help if you have trouble concentrating or focusing.
LucerneAges 18 years+ - NCT06873464Enrolling by invitation
Brain stimulation to reduce fatigue in multiple sclerosis
This trial tests if a gentle brain stimulation technique (tDCS) can help reduce fatigue and improve quality of life for people with multiple sclerosis. You would receive either real or placebo stimulation over several sessions to see if it helps you feel less tired.
MadridAges 18–75 - NCT06641271Enrolling by invitation
Vagus nerve stimulation with hand exercises for MS
This study tests if vagus nerve stimulation (a mild electrical pulse on the ear) combined with hand exercises can help repair the protective coating of your nerves and improve hand function in multiple sclerosis.
Aurora, ColoradoAges 18–70 - NCT05962177Recruiting
Study of blood tests and scans in relapsing-remitting MS
This study follows adults with relapsing-remitting multiple sclerosis using MRI scans and blood tests. It aims to understand how the disease behaves and what markers in blood and imaging may relate to changes over time.
MontpellierAges 18–59 - NCT06223074Enrolling by invitationPhase 2
Nasal Steroid Spray for MS Relapses
This study tests a nasal spray form of the steroid methylprednisolone for treating MS relapses. The goal is to see if this new way of taking the medicine works as well or better than standard treatments.
Mexico CityAges 18–65 - NCT04819737Recruiting
MRI scan study to better detect spinal cord changes in MS
This study tests new MRI scan methods to more clearly find spinal cord lesions in people with multiple sclerosis (MS). It may help improve how MS spinal cord changes are seen on scans.
BaselAges 18 years+ - NCT06865274Recruiting
A look at gene changes in MS, NMOSD, and MOGAD
This study looks at a specific gene change in people with MS, NMOSD, or MOGAD to see how common it is. By joining, you help researchers learn more about these conditions and possible future treatments.
Roma, RomaAges 18 years+ - NCT07304375Recruiting
Exercise and sleep effects on learning and abilities in MS
This trial tests how combining exercise and sleep monitoring can improve motor learning and daily function in people with early relapsing-remitting multiple sclerosis. It may help you move better and feel more capable in daily life.
CopenhagenAges 18–70 - NCT06956326RecruitingPhase 2
Early rehab for multiple sclerosis relapse recovery
This trial tests whether early and specialized rehabilitation can help people with multiple sclerosis recover better after a motor relapse. It is for people who are already staying at a Danish MS Hospital for rehab.
HaslevAges 18 years+ - NCT07086950Recruiting
Brain training game for thinking skills in multiple sclerosis
This study tests a fun brain-training game designed to improve thinking and memory in people with multiple sclerosis. It may help with everyday mental tasks like concentrating and processing information.
Lausanne, Canton of VaudAges 18 years+ - NCT06890923RecruitingPhase 2
Nasal foralumab for non-active secondary progressive MS
This trial tests a nasal spray medication, foralumab, to see if it can help people with non-active secondary progressive multiple sclerosis. It is only for people who completed a previous related study (TILS-021).
Boston, MassachusettsAges 18–75 - NCT06796504Recruiting
Nerve stimulation for relapsing-remitting multiple sclerosis
This trial tests a device that stimulates a nerve in the neck, which may help repair the protective coating around nerves in the brain and spinal cord. It is for people with relapsing-remitting MS who are stable on their current medication and have some vision problems due to MS.
Irvine, CaliforniaAges 22–60
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Common questions
- Are there clinical trials for multiple sclerosis?
- Yes. Clin2 currently lists 428 recruiting multiple sclerosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a multiple sclerosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a multiple sclerosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Multiple Sclerosis, Relapsing-Remitting
- Multiple Sclerosis (MS) - Relapsing-remitting
- Multiple Sclerosis, Secondary Progressive
- Relapsing Multiple Sclerosis
- Multiple Sclerosis, Primary Progressive
- Progressive Multiple Sclerosis
- Multiple Sclerosis (MS) Primary Progressive
- Multiple Sclerosis (MS) Secondary Progressive
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.