Clinical trials
Multiple sclerosis clinical trials
A condition in which the immune system attacks the protective covering of nerves. We’re tracking 443 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06826638Recruiting
Brain activity during arm exercises for MS and healthy volunteers
This study looks at brain activity during task-oriented arm exercises to understand how neurorehabilitation works. It may help people with multiple sclerosis (MS) and healthy volunteers improve motor function.
GenovaAges 18–60 - NCT06860932Recruiting
Palliative care program for MS and related disorders
This study tests a palliative care program designed to help people with long-term neurological conditions like MS, NMOSD, or anti-MOG disease. You will learn about managing symptoms and planning care, and the study will measure how this affects your knowledge and attitudes.
New York, New YorkAges 18–65 - NCT06920524Recruiting
Music therapy for stress during botox injections
This study tests whether listening to music can reduce stress and anxiety during botulinum toxin (botox) injections for muscle spasticity. It may help you feel more calm and comfortable during treatment.
Clermont-FerrandAges 18 years+ - NCT06937723Recruiting
App-based monitoring for spasticity in multiple sclerosis
This trial tests if a smartphone app can help monitor spasticity (muscle tightness or stiffness) in people with multiple sclerosis. If you have MS and spasticity that needs treatment, using your own smartphone might help track your health.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT06939166RecruitingEarly Phase 1
Immune cell therapy for relapsed neurological autoimmune diseases
This trial tests a new type of immune cell therapy (CAR T-cells) that targets CD19 and BCMA proteins on B cells. It is for people with certain neurological autoimmune diseases that have come back or not responded to standard treatments. The goal is to see if this therapy can help control the disease.
TianjinAges 18 years+ - NCT06940323Recruiting
Pregnancy study for women with chronic conditions
This study tracks pregnant women with certain chronic health conditions (like multiple sclerosis, lupus, or rheumatoid arthritis) and healthy pregnant women as a comparison group. It aims to understand how these conditions and their treatments affect pregnancy, the baby, and breast milk.
San Francisco, CaliforniaAges 18–64 - NCT06968039Recruiting
Personalized brain stimulation for cognitive issues in demyelinating diseases
This trial tests a personalized form of electrical brain stimulation to improve cognitive problems like memory and thinking speed in people with conditions that damage the protective coating around nerves. It aims to see if this treatment can help with day-to-day thinking challenges.
Beijing, Beijing MunicipalityAges 18–65 - NCT06986278Recruiting
Treadmill training plus brain stimulation for multiple sclerosis
This trial combines treadmill training with a gentle brain stimulation technique (tDCS) to see if it can help people with Multiple Sclerosis walk better. The study is for people with stable MS and mild to moderate disability.
Toledo, ToledoAges 18 years+ - NCT06999434RecruitingPhase 1
Testing a new PET scan for nerve coating damage
This study uses a special PET scan tracer to look at the protective coating of nerves in the brain. It aims to help doctors see and measure damage to this coating, which can happen in diseases like multiple sclerosis. The trial is open to healthy volunteers to test this new imaging method.
New Haven, ConnecticutAges 18–90 - NCT07083856Recruiting
Reiki and self-acupressure for people with MS
This study tests two relaxing therapies — Reiki (a gentle hands-on energy technique) and self-acupressure (applying mild finger pressure on specific points) — for people with multiple sclerosis. It looks at how these treatments affect symptoms like anxiety, depression, and fatigue.
Muğla, Fethi̇yeAges 18–75 - NCT07085507RecruitingPhase 1/Phase 2
Testing a new drug for multiple sclerosis in healthy people and MS patients
This trial tests an experimental oral drug called VT7208 in both healthy volunteers and people with multiple sclerosis (MS). The goal is to see if it is safe and how the body processes it, which could lead to a new treatment option for MS.
Adelaide, South AustraliaAges 18–65 - NCT07087106RecruitingPhase 4
Glucose use in the brain of people with MS
This study uses a special PET scan to see how the brain uses sugar (glucose) in people with multiple sclerosis (MS) compared to healthy volunteers. It may help researchers understand energy changes in the brain related to MS.
Boston, MassachusettsAges 18–70 - NCT07087873Recruiting
Testing brain stimulation for memory problems in inflammatory diseases
This trial tests if a gentle electrical current applied to the scalp can improve memory and thinking in people with certain inflammatory conditions that affect the brain and spinal cord.
Beijing, Beijing MunicipalityAges 18–60 - NCT07132775Recruiting
Full-body electrical stimulation suit for spasticity and pain
This study tests a full-body suit that uses mild electrical stimulation to help reduce spasticity, pain, and overactive reflexes in people with conditions like Multiple Sclerosis or Fibromyalgia. It aims to see if the suit is safe and can improve comfort and movement.
Chicago, IllinoisAges 18–75 - NCT07151534Recruiting
Body awareness, trunk stability, and arm function in MS
This study explores how body awareness and trunk stability relate to arm function in people with multiple sclerosis (MS). It aims to understand these connections to help improve rehabilitation for MS patients.
Ankara, AltındağAges 10 years+ - NCT07159789Recruiting
Brain stimulation to improve leg weakness in MS
This study tests whether a noninvasive brain stimulation technique (rTMS) can help people with multiple sclerosis who have leg stiffness and weakness. You will receive daily sessions over two weeks to see if it improves walking and quality of life.
Gatineau, QuebecAges 18–70 - NCT07183683Recruiting
Acupuncture for bladder problems in women with MS
This study tests whether stimulating acupuncture points on the lower leg can help women with multiple sclerosis who have overactive bladder symptoms like urgency, frequent urination, or leaking. It is for women with relapsing-remitting MS who are not using a catheter regularly.
Berlin, State of BerlinAges 18–60 - NCT07225868Recruiting
Coaching to boost cognitive rehab in MS
This trial tests if coaching in goal-directed behavior can improve cognitive rehabilitation for people with relapsing-remitting or secondary progressive MS. It aims to help patients better manage daily tasks and thinking challenges.
Buffalo, New YorkAges 18–65 - NCT07230015Recruiting
Imagery and balance training for MS
This study tests if combining mental practice of movements with balance exercises helps people with relapsing-remitting MS who have mild balance problems and dizziness. It aims to improve stability and reduce vertigo.
Istanbul, Beykoz/İstanbulAges 18–45 - NCT07236684Recruiting
MS Bladder Control: Study of Muscle Activity
This study looks at how well the pelvic floor muscles work in people with MS who have bladder control problems. It may help find better ways to manage urinary incontinence.
IstanbulAges 30–50 - NCT07289724Recruiting
Improving care for people with multiple sclerosis
This trial aims to develop a new care model for people with multiple sclerosis (MS). It includes patients, caregivers, and healthcare professionals to ensure the best care possible.
ParisAges 18 years+ - NCT07303582RecruitingPhase 4
Freezing nerves to ease pain from muscle tightness
This study tests if freezing specific nerves (cryoneurolysis) can reduce pain caused by muscle tightness (spasticity) after a brain or spinal cord injury, or from multiple sclerosis. It is for people who already get Botox injections for this pain.
OxfordAges 18 years+ - NCT07313462Recruiting
Comparing treatment strategies for MS starting after age 50
This trial looks at two ways to treat multiple sclerosis (MS) that begins after age 50. It compares starting with a stronger medication right away versus starting with a milder one and then switching if needed.
StrasbourgAges 50 years+ - NCT07337785RecruitingEarly Phase 1
CAR-T cell therapy for autoimmune diseases
This trial tests a new kind of cell therapy (UCAR-T) that targets CD19 and BCMA proteins on immune cells. It is for people with certain neurological autoimmune diseases like multiple sclerosis, myasthenia gravis, chronic inflammatory demyelinating polyneuropathy, or autoimmune encephalitis who have not responded well to standard treatments.
Wuhan, HubeiAges 18–70
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Common questions
- Are there clinical trials for multiple sclerosis?
- Yes. Clin2 currently lists 443 recruiting multiple sclerosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a multiple sclerosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a multiple sclerosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Multiple Sclerosis, Relapsing-Remitting
- Multiple Sclerosis (MS) - Relapsing-remitting
- Multiple Sclerosis, Secondary Progressive
- Relapsing Multiple Sclerosis
- Multiple Sclerosis, Primary Progressive
- Progressive Multiple Sclerosis
- Multiple Sclerosis (MS) Primary Progressive
- Multiple Sclerosis (MS) Secondary Progressive
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.