Clinical trials
Multiple sclerosis clinical trials
A condition in which the immune system attacks the protective covering of nerves. We’re tracking 428 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07225361RecruitingPhase 4
Ublituximab for early relapsing multiple sclerosis
This study tests ublituximab (Briumvi), a treatment given as an infusion, for people recently diagnosed with relapsing MS. The goal is to see if starting this treatment early helps control MS better.
Chicago, IllinoisAges 18–70 - NCT07224373RecruitingPhase 1
A study of AZD0120 for multiple sclerosis
This trial tests an experimental drug called AZD0120 in adults with multiple sclerosis. It is designed for people with relapsing or progressive forms of MS who have not responded well to other treatments or have active disease.
Tucson, ArizonaAges 18–60 - NCT07202195Recruiting
Using stimulation suits at home for MS symptoms
This trial tests whether wearing a special suit at home can help manage muscle stiffness (spasticity) or lack of coordination (ataxia) caused by multiple sclerosis. The suit delivers gentle stimulation to improve movement in your arms or legs.
SteenokkerzeelAges 18 years+ - NCT07193823Recruiting
Sexual function study for women with MS
This study looks at sexual health in women with relapsing-remitting multiple sclerosis. It aims to understand how MS might affect sexual function and to find ways to help.
Izmir, BornovaAges 25–50 - NCT07202780Enrolling by invitation
MS and Muscle Strength in Breathing and Legs
This study looks at how MS affects the strength of your breathing muscles and leg muscles. If you join, you will have tests to measure your muscle strength, walking ability, and fatigue. This may help doctors understand how to better treat MS-related weakness.
Gaziantep, şehitkamilAges 18–50 - NCT07174973Recruiting
New balance training for better stability in MS
This study tests two new balance-training programs for people with Multiple Sclerosis. One program combines balance exercises with mild electrical stimulation on the legs, while the other uses walking exercises on a treadmill with special visual feedback. Both aim to improve balance and help your brain make new connections.
Toronto, OntarioAges 18–65 - NCT07178431RecruitingPhase 1/Phase 2
CAR T-cell therapy for worsening multiple sclerosis
This trial tests a new treatment called MB-CART2019.1, which uses your own immune cells to fight multiple sclerosis. It is for people with progressive or worsening MS who have not responded well to other treatments.
BerlinAges 18–55 - NCT06949696Recruiting
Dual-task training and cognitive rehab for MS patients
This study tests whether combining physical and mental exercises can improve walking and thinking for people with multiple sclerosis. It may help if you have mild disability and haven't had a recent relapse.
MersinAges 18–65 - NCT07168772Recruiting
Probiotic supplement for multiple sclerosis
This study tests whether adding a probiotic supplement to your usual MS treatment (or to no treatment) can help manage relapsing-remitting multiple sclerosis. It aims to see if the probiotic is safe and beneficial as an add-on therapy.
Barcelona, BarcelonaAges 18–60 - NCT07116070Recruiting
Sarcopenia and muscle loss in multiple sclerosis patients
This study looks at muscle loss (sarcopenia) in people with multiple sclerosis. It aims to understand what factors are linked to muscle loss, which could help improve care.
Konya, SelcukluAges 18 years+ - NCT07115017Recruiting
Testing a new PET scan tracer for brain inflammation in MS
This study uses a new radioactive tracer called [18F]-FZTA during a PET scan to see inflammation in the brain. Researchers want to test this tracer in both healthy adults and people with multiple sclerosis (MS) to see if it can help detect MS activity.
St Louis, MissouriAges 18 years+ - NCT07111637Recruiting
AI-assisted MRI for multiple sclerosis care
This trial is testing whether an artificial intelligence tool can improve the quality of MRI scans for people with MS. It aims to make scans faster, better, and more equitable for everyone in the NHS.
LondonAges 18–99 - NCT07096700Recruiting
VR and wearable brace for multiple sclerosis rehabilitation
This trial tests whether combining virtual reality exercises with a leg brace can help people with multiple sclerosis improve their walking and balance. If you have mild to moderate disability and can use the Exoband brace, you may be eligible.
Bologna, BolognaAges 18–65 - NCT02980640Recruiting
Swiss Multiple Sclerosis Registry for adults with MS
This registry enrolls people with a confirmed diagnosis of multiple sclerosis (MS) who are age 18 or older and live in Switzerland (or receive their MS care there). It helps researchers better understand MS in the Swiss population and may improve future studies and care.
Zurich, Canton of ZurichAges 18 years+ - NCT06981013Recruiting
Weighted Torso Study for Balance in MS
This study tests if adding weight to your torso affects how your muscles work during balance tests. It may help researchers understand how to improve balance for people with MS.
Saint Augustine, FloridaAges 18–75 - NCT07067463RecruitingPhase 3
Testing orelabrutinib for primary progressive MS
This trial tests a daily pill called orelabrutinib to see if it can slow disability progression in people with primary progressive multiple sclerosis (PPMS). It may be an option for patients whose symptoms have been getting worse over the past two years.
Pheonix, ArizonaAges 18–60 - NCT03401879Recruiting
Study eye blood-flow changes in multiple sclerosis
This study measures how blood flow in the eye changes in people with relapsing-remitting multiple sclerosis (RRMS) who previously had optic neuritis. The goal is to understand eye/brain blood-flow signals and how they may relate to MS.
Vienna, AustriaAges 18 years+ - NCT07033975Recruiting
Specialized diet for multiple sclerosis
This trial is testing a specialized diet for people with multiple sclerosis (MS) who are not too severely disabled. You may be able to join if you have mild to moderate MS and do not have a diagnosed digestive disorder.
Diepenbeek, LimburgAges 30–65 - NCT07025122Enrolling by invitation
Fatigue in MS and its link to inflammation
This study looks at how fatigue in multiple sclerosis (MS) relates to signs of inflammation and nerve damage. It may help understand why fatigue happens and improve treatment.
Martin, SlovakiaAges 18 years+ - NCT07012135Recruiting
Autonomic Function in Multiple Sclerosis
This study looks at how the nervous system controls automatic body functions (like heart rate and blood pressure) in people with multiple sclerosis. Researchers want to compare results between people with MS and healthy volunteers to understand how MS affects these functions.
Rochester, MinnesotaAges 18–50 - NCT07011875Enrolling by invitation
Physical activity and period pain in women with MS
This study looks at how physical activity levels affect period pain, menstrual symptoms, and emotional well-being in women with multiple sclerosis. It aims to find out if being more active can help with these issues.
Karabük, Karabük ProvinceAges 18–55 - NCT06992115Recruiting
MIND diet study for people with multiple sclerosis
This study tests whether following the MIND diet, a diet designed to support brain health, can help people with multiple sclerosis. You'll follow the diet and the researchers will see how it affects your health.
New York, New YorkAges 18–70 - NCT06394310Recruiting
Dry needling for leg tightness in MS
This study tests whether dry needling (a therapy using thin needles to release muscle tightness) can help reduce leg stiffness and improve walking in people with multiple sclerosis. If you have leg spasticity and can walk with some help, this trial may be a good fit.
Kansas City, KansasAges 18–64 - NCT06875908Recruiting
Turkish sleep survey test for multiple sclerosis
This study tests a Turkish-language sleep survey for people with multiple sclerosis. It aims to see if the survey is a reliable way to measure sleep problems in MS patients.
Bağcılar, IstanbulAges 18–65
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Common questions
- Are there clinical trials for multiple sclerosis?
- Yes. Clin2 currently lists 428 recruiting multiple sclerosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a multiple sclerosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a multiple sclerosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Multiple Sclerosis, Relapsing-Remitting
- Multiple Sclerosis (MS) - Relapsing-remitting
- Multiple Sclerosis, Secondary Progressive
- Relapsing Multiple Sclerosis
- Multiple Sclerosis, Primary Progressive
- Progressive Multiple Sclerosis
- Multiple Sclerosis (MS) Primary Progressive
- Multiple Sclerosis (MS) Secondary Progressive
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.