Clinical trials
Multiple sclerosis clinical trials
A condition in which the immune system attacks the protective covering of nerves. We’re tracking 428 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06919900Recruiting
Learning fall-resistant skills in multiple sclerosis
This trial tests if practicing slips and trips can help people with multiple sclerosis learn to prevent falls. You will be exposed to controlled slips and trips to improve your balance and walking safety.
Atlanta, GeorgiaAges 45–89 - NCT03910738RecruitingPhase 2
Testosterone treatment for nerve protection and myelin repair in MS
This Phase 2 study tests whether taking testosterone (for low testosterone levels) can help protect nerves and repair myelin in people with relapsing-remitting multiple sclerosis (MS). It may be most relevant if your MS is stable and you have low blood testosterone without current androgen treatment.
BesançonAges 18–55 - NCT06874764Enrolling by invitation
Training with a wireless system for thinking and reaction in MS
This study tests whether a special wireless reaction training system can help improve thinking and reaction speed in people with multiple sclerosis (MS). It compares this training to standard exercises to see which works better for your brain health.
Izmir, BornovaAges 18–55 - NCT06864936Recruiting
Eye scan study for ublituximab in multiple sclerosis
This study uses a special eye scan (OCT) to see how well the MS medication ublituximab works. It compares people starting ublituximab to those on other stable MS treatments, to find better ways to measure treatment success.
Baltimore, MarylandAges 18–65 - NCT06849960Enrolling by invitation
Reliability and validity of the Two-minute Test for Multiple Sclerosis
This study tests whether a simple two-minute walking test is a reliable way to measure function in people with multiple sclerosis. It aims to help doctors and patients understand the true value of this quick, easy test.
Şehitkamil, GaziantepAges 18–65 - NCT06312046Recruiting
Thinking and Movement in MS: A Balance Study
This study tests how thinking and movement interact in people with MS who have some balance problems. It aims to find ways to improve daily function.
Stockholm, Stockholm CountyAges 18–65 - NCT05983809Recruiting
Balance and walking rehab using technology for MS
This trial tests a new type of balance and walking training for people with multiple sclerosis. It uses technology to help improve your stability and gait, which may help you move more safely and confidently.
Roma, RMAges 18–65 - NCT06495138Recruiting
Eye exercises for dizziness in multiple sclerosis
This study tests a new type of eye exercise to help with dizziness and balance problems in people with multiple sclerosis (MS). The exercise involves moving your head and eyes in a specific way to retrain your balance system.
Atlanta, GeorgiaAges 18–89 - NCT05532943RecruitingPhase 1/Phase 2
Cord stem cell treatment for people with multiple sclerosis
This Phase 1/2 trial studies whether donated umbilical cord stem cells are safe and can improve multiple sclerosis. It aims to see if the treatment is workable for people who still have active MS despite standard therapies.
Taichung, Non-USAges 20–65 - NCT06592352RecruitingPhase 2
Modafinil for thinking problems in MS
This study tests whether the medication modafinil can improve thinking and memory problems in people with MS. If you have MS and notice cognitive changes like forgetfulness or trouble focusing, you may be eligible.
BragaAges 18–64 - NCT06676618Recruiting
Exercise training for multiple sclerosis patients
This study tests a multimodal exercise program for people with multiple sclerosis. It aims to improve mobility, strength, and overall well-being through guided exercises you can do at home.
Istanbul, BuyukcekmeceAges 20–65 - NCT06629428RecruitingEarly Phase 1
Study of ublituximab for walking and movement in multiple sclerosis
This trial tests if ublituximab can improve walking and other motor skills in people with active relapsing MS. You must be able to walk at least 25 feet and stand 30 seconds on your own.
Atlanta, GeorgiaAges 18–55 - NCT05124600Recruiting
Personalized MS app study for 21-day daily use
This study looks at an individualized health eLibrary app for people with multiple sclerosis (MS). You may use the app for 21 days and help researchers compare outcomes between a group using the app and a comparison group.
Champaign, IllinoisAges 18 years+ - NCT06592703RecruitingPhase 1
Stem cells for primary progressive MS
This study tests whether stem cells from donated fat tissue can slow down primary progressive multiple sclerosis. You would receive a single injection of the cells into your spinal fluid and be followed for up to 2 years.
CréteilAges 18–55 - NCT06569550Recruiting
Fatigue treatment study for multiple sclerosis
This trial tests a brain stimulation therapy designed to reduce fatigue in people with multiple sclerosis. If you experience moderate to severe fatigue and have a stable medication routine, this study might help determine if a non-invasive treatment can improve your energy levels.
Hvidovre, Capital RegionAges 18–65 - NCT06526364Recruiting
Multiple sclerosis study with smartphone app tracking
This study follows people with multiple sclerosis over time using a smartphone app and clinic visits. It aims to better understand the disease and improve care.
BaselAges 18 years+ - NCT06495593Enrolling by invitationPhase 4
Ocrelizumab's effect on immune cells in lymph nodes in MS
This study tests how ocrelizumab, a medication for MS, affects immune cells in your lymph nodes. It may help doctors understand how the drug works and why it helps some people more than others.
San Francisco, CaliforniaAges 18–65 - NCT06441617Enrolling by invitation
Online program to reduce fatigue in multiple sclerosis
This trial tests an online self-management program to help reduce fatigue in people with MS. You'll use a website or app over 24 weeks, and researchers will check how well it works.
Washington D.C., District of ColumbiaAges 22 years+ - NCT06433752Recruiting
Study of BRIUMVI for relapsing multiple sclerosis
This study looks at how well BRIUMVI (a medicine for relapsing multiple sclerosis) works for people in everyday life. Researchers want to see how people do when they first start the medication.
Birmingham, AlabamaAges 18 years+ - NCT06408259RecruitingPhase 3
Comparing ozanimod and fingolimod for children with MS
This study compares two oral medications, ozanimod and fingolimod, to see which one works better and is safer for children and teenagers with relapsing-remitting MS. Both drugs help reduce MS attacks and slow down the disease.
Loma Linda, CaliforniaAges 10–17 - NCT06390930Recruiting
Breathing bursts of lower oxygen for hand function in MS
This study tests whether breathing short bursts of reduced oxygen (acute intermittent hypoxia) can improve hand function and nerve health in people with relapsing-remitting MS who have some hand weakness.
Chicago, IllinoisAges 18–75 - NCT06341023Recruiting
Balance training for older adults with MS
This study tests a balance training program for people with MS who have mild walking and memory difficulties. It aims to improve balance and prevent falls.
Chicago, IllinoisAges 18–90 - NCT04121468RecruitingPhase 1/Phase 2
Metformin trial for vision nerve recovery in young people with MS
This study tests whether metformin can help “reset” damaged nerve cells in the brain and improve vision-related nerve problems in children and young adults with multiple sclerosis. Participants are assigned to metformin or a comparison treatment in a blinded (not everyone knows which) study.
Toronto, OntarioAges 10–25 - NCT05964829Recruiting
Test a leg sleeve to improve walking in multiple sclerosis
This trial studies whether using the Cionic “Neural Sleeve” can improve walking and leg movement in people with multiple sclerosis (MS). It may help if your MS affects mobility, and you can safely wear and tolerate the device during the day.
Cleveland, OhioAges 22–75
Hear when a new Multiple sclerosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for multiple sclerosis?
- Yes. Clin2 currently lists 428 recruiting multiple sclerosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a multiple sclerosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a multiple sclerosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Multiple Sclerosis, Relapsing-Remitting
- Multiple Sclerosis (MS) - Relapsing-remitting
- Multiple Sclerosis, Secondary Progressive
- Relapsing Multiple Sclerosis
- Multiple Sclerosis, Primary Progressive
- Progressive Multiple Sclerosis
- Multiple Sclerosis (MS) Primary Progressive
- Multiple Sclerosis (MS) Secondary Progressive
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.