Clinical trials
Multiple sclerosis clinical trials
A condition in which the immune system attacks the protective covering of nerves. We’re tracking 443 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06919900Recruiting
Learning fall-resistant skills in multiple sclerosis
This trial tests if practicing slips and trips can help people with multiple sclerosis learn to prevent falls. You will be exposed to controlled slips and trips to improve your balance and walking safety.
Atlanta, GeorgiaAges 45–89 - NCT06949696Recruiting
Dual-task training and cognitive rehab for MS patients
This study tests whether combining physical and mental exercises can improve walking and thinking for people with multiple sclerosis. It may help if you have mild disability and haven't had a recent relapse.
MersinAges 18–65 - NCT06981013Recruiting
Weighted Torso Study for Balance in MS
This study tests if adding weight to your torso affects how your muscles work during balance tests. It may help researchers understand how to improve balance for people with MS.
Saint Augustine, FloridaAges 18–75 - NCT06992115Recruiting
MIND diet study for people with multiple sclerosis
This trial tests whether the MIND diet, which is a healthy eating plan, can help people with multiple sclerosis (MS) manage their condition. It is designed for people with MS who currently don't follow the MIND diet very closely.
New York, New YorkAges 18–70 - NCT07012135Recruiting
Autonomic Function in Multiple Sclerosis
This study looks at how the nervous system controls automatic body functions (like heart rate and blood pressure) in people with multiple sclerosis. Researchers want to compare results between people with MS and healthy volunteers to understand how MS affects these functions.
Rochester, MinnesotaAges 18–50 - NCT07033975Recruiting
Specialized diet for multiple sclerosis
This trial is testing a specialized diet for people with multiple sclerosis (MS) who are not too severely disabled. You may be able to join if you have mild to moderate MS and do not have a diagnosed digestive disorder.
Diepenbeek, LimburgAges 30–65 - NCT07096700Recruiting
VR and wearable brace for multiple sclerosis rehabilitation
This trial tests whether combining virtual reality exercises with a leg brace can help people with multiple sclerosis improve their walking and balance. If you have mild to moderate disability and can use the Exoband brace, you may be eligible.
Bologna, BolognaAges 18–65 - NCT07115017Recruiting
Testing a new PET scan tracer for brain inflammation in MS
This study uses a new radioactive tracer called [18F]-FZTA during a PET scan to see inflammation in the brain. Researchers want to test this tracer in both healthy adults and people with multiple sclerosis (MS) to see if it can help detect MS activity.
St Louis, MissouriAges 18 years+ - NCT07116070Recruiting
Sarcopenia and muscle loss in multiple sclerosis patients
This study looks at muscle loss (sarcopenia) in people with multiple sclerosis. It aims to understand what factors are linked to muscle loss, which could help improve care.
Konya, SelcukluAges 18 years+ - NCT07174973Recruiting
New balance training for better stability in MS
This study tests two new balance-training programs for people with Multiple Sclerosis. One program combines balance exercises with mild electrical stimulation on the legs, while the other uses walking exercises on a treadmill with special visual feedback. Both aim to improve balance and help your brain make new connections.
Toronto, OntarioAges 18–65 - NCT07178431RecruitingPhase 1/Phase 2
CAR T-cell therapy for worsening multiple sclerosis
This trial tests a new treatment called MB-CART2019.1, which uses your own immune cells to fight multiple sclerosis. It is for people with progressive or worsening MS who have not responded well to other treatments.
BerlinAges 18–55 - NCT07193823Recruiting
Sexual function study for women with MS
This study looks at sexual health in women with relapsing-remitting multiple sclerosis. It aims to understand how MS might affect sexual function and to find ways to help.
Izmir, BornovaAges 25–50 - NCT07202195Recruiting
Using stimulation suits at home for MS symptoms
This trial tests whether wearing a special suit at home can help manage muscle stiffness (spasticity) or lack of coordination (ataxia) caused by multiple sclerosis. The suit delivers gentle stimulation to improve movement in your arms or legs.
SteenokkerzeelAges 18 years+ - NCT07222618Recruiting
Selfie videos to measure function in MS
This trial asks people with MS to record short 'selfie' videos of themselves doing everyday tasks, like walking or getting dressed. The goal is to find a better, more personal way to measure how MS affects daily function.
San Francisco, CaliforniaAges 18 years+ - NCT07225361RecruitingPhase 4
Ublituximab for early relapsing multiple sclerosis
This study tests ublituximab (Briumvi), a treatment given as an infusion, for people recently diagnosed with relapsing MS. The goal is to see if starting this treatment early helps control MS better.
Chicago, IllinoisAges 18–70 - NCT05359653RecruitingPhase 1/Phase 2
Clemastine to study MRI changes in relapsing MS
This early-phase study tests whether clemastine (a drug being studied for “myelin repair”) changes how MS looks on special MRI scans. It may help researchers understand if the treatment supports restoring nerve covering in people with relapsing-remitting MS.
San Francisco, CaliforniaAges 18–55 - NCT07252895Recruiting
Testing the EXOPULSE Suit for walking in multiple sclerosis
This trial tests whether the EXOPULSE Suit can help people with multiple sclerosis walk better. You will try the suit and we will measure how it affects your walking over time.
BerckAges 18 years+ - NCT07303790RecruitingEarly Phase 1
Study of GC012F for people with multiple sclerosis
This early phase trial tests a new treatment called GC012F for people with multiple sclerosis. It aims to see how safe and tolerable it is, and may offer a new option for those whose current treatments are not working well enough.
Hubei, HubeiAges 18 years+ - NCT07342777Recruiting
Exercise for Pain Relief in Multiple Sclerosis
This study tests whether exercise can help reduce pain in people with multiple sclerosis. If you have MS and moderate to severe pain, you may be asked to participate in a supervised exercise program.
Aarhus, DenmarkAges 18 years+ - NCT07497399RecruitingPhase 2
Testing a diabetes drug for weight loss in MS
This trial tests if a GLP-1 receptor agonist can help people with multiple sclerosis who have a high BMI. It may reduce inflammation and improve health.
Baltimore, MarylandAges 18–60 - NCT07355387Recruiting
Home-based balance training for multiple sclerosis
This study tests a 12-week home-based balance training program for people with multiple sclerosis. Sessions are done online with a helper present, and the goal is to improve walking and reduce fall risk.
Chicago, IllinoisAges 40–90 - NCT07388992Recruiting
Walking patterns in people with MS
This study uses special sensors to compare walking patterns in people with multiple sclerosis (MS) and healthy volunteers. The goal is to see how MS affects walking over time, which may lead to better ways to track and treat movement problems.
LilleAges 18–65 - NCT07389590RecruitingPhase 4
Switching MS drugs for wearing-off symptoms
This study tests whether switching from ocrelizumab to a similar drug, ublituximab, can help people with MS who experience 'wearing-off' symptoms before their next infusion. It may offer a new option to keep symptoms more stable between doses.
Baltimore, MarylandAges 18–65 - NCT01703429Recruiting
Alternative care program for people with multiple sclerosis
This study looks at how a complementary or alternative care approach affects people living with multiple sclerosis. It may help to understand whether this type of program improves symptoms or quality of life over time.
Kenmore, WashingtonAges 18–100
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Common questions
- Are there clinical trials for multiple sclerosis?
- Yes. Clin2 currently lists 443 recruiting multiple sclerosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a multiple sclerosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a multiple sclerosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Multiple Sclerosis, Relapsing-Remitting
- Multiple Sclerosis (MS) - Relapsing-remitting
- Multiple Sclerosis, Secondary Progressive
- Relapsing Multiple Sclerosis
- Multiple Sclerosis, Primary Progressive
- Progressive Multiple Sclerosis
- Multiple Sclerosis (MS) Primary Progressive
- Multiple Sclerosis (MS) Secondary Progressive
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.