Clinical trials
Musculoskeletal clinical trials
Below are recruiting musculoskeletal clinical trials, each written for real people, not researchers. We’re tracking 217 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06749509Enrolling by invitation
Musculoskeletal rehab courses and work ability study
This study looks at whether face-to-face or online rehabilitation courses help people with musculoskeletal disorders stay at work or return to work. It compares these courses to standard care.
HelsinkiAges 18 years+ - NCT06488547Recruiting
Stress and muscle health study for Greek workers
This trial looks at how stress affects muscle and bone health in employees. If you join, you'll answer questions and be measured with simple electronic devices. The goal is to find ways to help workers stay healthy.
Larissa, Biopolis- LarissaAges 19 years+ - NCT07447219Recruiting
Ergonomics program for dental workers
This study tests an ergonomics program designed to reduce muscle and bone pain in dental healthcare workers. If you are a practicing dental professional, this program may help you prevent work-related injuries.
Serdang, SelangorAges 25–65 - NCT07513142Enrolling by invitationPhase 4
Platelet-Rich Plasma vs. Steroids for Thigh Muscle Injuries
This study compares two injection treatments for thigh muscle injuries in young athletes: platelet-rich plasma (PRP), which uses your own blood cells to promote healing, versus corticosteroids, which reduce inflammation. The goal is to see which works better to get you back to sports.
Gulf Breeze, FloridaAges 15–30 - NCT03707288Recruiting
Exercise study for neck and low back pain in medical students
This study looks at neck and low back pain in medical students and asks participants to follow a set exercise plan for a period of time. It may help researchers understand what kind of exercise support could improve symptoms in students.
Kingston, KingstonAges Any age - NCT05122728Recruiting
Tracking injury risk after concussion and body movement changes
This study looks at how being recently concussion-affected changes musculoskeletal (muscle/joint) injury risk and recovery during physical activity. It compares a group who is currently recovering after concussion with a similar healthy group to better understand risk factors over time.
Athens, GeorgiaAges 18–40 - NCT06380530Recruiting
Computer-assisted surgical planning for limb deformity correction
This trial tests a new computer-assisted planning method to help surgeons better correct bone deformities in the arms or legs. It may lead to more precise surgeries and faster recovery.
Bologna, BOAges 2–40 - NCT07194239Recruiting
Lifestyle medicine for chronic pain in older adults
This trial tests if lifestyle changes like diet and exercise can reduce chronic muscle or joint pain in older adults. It focuses on people with long-lasting pain from conditions like arthritis.
Hong KongAges 60 years+ - NCT05700526Enrolling by invitation
3D-printed customized bone grafts for children’s limb problems
This trial is testing 3D-printed, customized bone grafts made from donor bone to help children and teens stabilize corrective surgery for limb bone alignment. It may help patients who need a planned bone cut (osteotomy) plus a large bone graft to hold the correction in place.
BolognaAges 2–18 - NCT07764354Recruiting
Patient education for sticking with home exercises
This study tests whether extra education helps people with chronic musculoskeletal conditions—like long-term back pain, knee arthritis, or partial rotator cuff tears—stick with their home exercise routines to feel better. If you have one of these conditions and are willing to follow a home exercise plan, this could help you manage pain.
Dammam, Eastern ProvinceAges Any age - NCT05780502Recruiting
Orthotic and rehab program for lower-limb musculoskeletal problems
This study tests an integrated brace (an exoskeletal orthosis) plus a rehabilitation plan for problems in the legs/lower limbs. It may help improve how you move and function while using a custom brace.
Charlotte, North CarolinaAges 18 years+ - NCT06074783RecruitingPhase 1/Phase 2
Stem cell therapy for muscle and joint injuries
This study tests a new therapy made from donor stem cells that may help repair damaged muscles, bones, tendons, and joints. It is for people whose injuries or degenerative conditions have not healed on their own.
Nassau, The BahamasAges 18 years+ - NCT06820073Recruiting
Stretching study for office workers with neck or back pain
This study tests if a gentle stretching method using a special hammock can help reduce neck and back discomfort for people who sit at work. It's looking for volunteers who have some aches but no serious diagnoses.
Zaragoza, ZaragozaAges 18–65 - NCT06535633Recruiting
Exercise program for older adults with chronic pain
This study looks at whether a community exercise program can help older adults with long-term muscle or joint pain. It is designed for people who are not already active and want to try a gentle, guided exercise program.
LimerickAges 50 years+ - NCT07001449Recruiting
Pain education for chronic muscle or joint pain
This study tests a type of pain education that focuses on communication to help people with long-term muscle or joint pain. It aims to see if learning about pain in a new way can help reduce symptoms and improve quality of life.
Lamia, Central GreeceAges 18–65 - NCT06709963Recruiting
Brain stimulation for older adults with chronic back or knee pain
This study tests a type of brain stimulation called intermittent theta burst stimulation to see if it can reduce pain and improve thinking in older adults with long-term back or knee pain. The treatment involves a non-invasive procedure that uses magnetic pulses to stimulate the brain.
Hong KongAges 60–85 - NCT06732687Recruiting
Exercise program to prevent injuries in school boys
This trial tests if a combination of bodyweight and jumping exercises can help prevent muscle and bone injuries in school-aged boys. It could be a good fit if your child is between 8 and 12 years old, has a normal weight, and hasn't had a recent injury.
Rawalpindi, Punjab ProvinceAges 8–12 - NCT06175884Recruiting
Communication skills for chronic muscle and joint pain
This trial tests how a physical therapist's communication style affects pain and function in people with long-term muscle or joint pain. Participants will fill out questionnaires and watch a video to see if better communication improves outcomes.
LamiaAges 18–65 - NCT06509087Recruiting
Combining CT and MRI for joint pain procedure
This study tests a procedure called transarterial microembolization for chronic shoulder or knee pain that hasn't improved with other treatments. It uses both CT and MRI to guide the procedure and see if it can help reduce pain.
TaipeiAges 20–80 - NCT03696134Recruiting
Study of musculoskeletal health, frailty, pain, and disability
This study looks at musculoskeletal health and wellbeing in adults, especially people who are frail or at risk of developing frailty-related problems like pain or limited ability to move. It may help researchers understand what puts people at risk and what could improve comfort and function.
NottinghamAges 18 years+ - NCT04800484Recruiting
Test how different AFO heel height and stiffness affect walking
This study looks at how changing the heel height and stiffness of an AFO (a brace you wear on your lower leg/foot) changes your walking pattern. The goal is to learn which brace settings may improve comfort and walking.
Iowa City, IowaAges 18–70 - NCT05220202Recruiting
Program for older vets with pain and depression
This trial tests a non-medicine (non-pharmacologic) home program to help older Veterans manage musculoskeletal pain and depressive symptoms at the same time. You may be assigned to one of two approaches, and you’ll need to be able to take part from home.
Dallas, TexasAges 60–99 - NCT05471752Recruiting
Study of special cells taken during orthopedic surgery
This study collects small cell samples from certain body tissues during planned orthopedic surgeries. The researchers will study these cells to understand their potential use in future treatments and to see if using them is safe and helpful.
MilanAges 18 years+ - NCT05701982Recruiting
Walking plus Tai Chi coach via video for COPD and pain
This study tests whether a phone/computer program that combines walking training with Tai Chi improves physical function (how well you move) in people who have COPD and long-term body or muscle pain. It may help you build strength, balance, and safer movement—especially if pain makes activity hard.
Boston, MassachusettsAges 40–100
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Common questions
- Are there clinical trials for musculoskeletal?
- Yes. Clin2 currently lists 217 recruiting musculoskeletal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.