Clinical trials
Musculoskeletal clinical trials
Below are recruiting musculoskeletal clinical trials, each written for real people, not researchers. We’re tracking 208 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05111925Recruiting
Testing after-injury and after-recovery readiness for full duty
This study looks at how well service members are able to return to full physical duty after a low-back or leg injury (or to see readiness in those without an injury). It may help improve return-to-duty planning by measuring changes before and after recovery.
Bethesda, MarylandAges 18–44 - NCT04580225Recruiting
Tested partial wrist fusion with or without bone removal
This study compares two surgical options for certain types of advanced wrist arthritis—one with partial wrist fusion alone, and one with partial wrist fusion plus removal of a small wrist bone. It may help find which approach works better for pain and function after surgery.
Calgary, AlbertaAges 18–75 - NCT04536103Recruiting
Accelerated MRI scans after ACL knee injury surgery
This trial tests a faster MRI scan method to measure healing in the knee after an ACL (anterior cruciate ligament) tear and reconstruction. It may help researchers compare scan quality while participants go through standard rehab.
Cleveland, OhioAges 18–50 - NCT04475640Recruiting
Genetic testing study for cancer patients in different ethnic groups
This study looks at cancer-related inherited gene changes using blood samples. It may help patients and doctors understand cancer risk and guide treatment planning, especially across different ethnic communities.
Scottsdale, ArizonaAges 18 years+ - NCT04251429Enrolling by invitation
Healthy workplace program for public healthcare workers
This trial studies a workplace program delivered by trained peers to improve health in public-sector healthcare facilities. You may be able to join if you are a direct employee of the agency that runs the facility.
Ages 18 years+ - NCT03510442Recruiting
Study of genetics and causes of systemic juvenile arthritis and Still's disease
This study aims to learn more about the causes and genetics of two related inflammatory conditions: systemic juvenile idiopathic arthritis (sJIA) in children and adult-onset Still's disease (AOSD) in adults. By studying patients and healthy volunteers, researchers hope to understand these diseases better and find better ways to treat them.
Bethesda, MarylandAges 1 day–100 years - NCT03442465Recruiting
Study of healing and function after bone reconstruction surgery
This study looks at how well people heal and how well they can move and use the repaired bone after reconstructive surgery for bone tumors. It may help doctors understand what recovery looks like and what could improve function over time.
Basking Ridge, New JerseyAges 4 years+ - NCT03441165Recruiting
Measure knee looseness during ACL and meniscus surgery
This trial checks how loose the knee feels during surgery for ACL reconstruction, ACL revision, or meniscus transplantation. The goal is to better assess knee stability during the operation, which may help surgeons choose the best repair.
Bologna, ItaliaAges 14–65 - NCT02471352Recruiting
Share skin samples for dermatology research
This study collects and stores biological samples (biospecimens) from people with skin conditions, people at risk, or healthy volunteers. It helps researchers better understand dermatologic diseases and support future skin research.
Bethesda, MarylandAges 1 day–100 years - NCT02504879Recruiting
Study of melorheostosis progression and genetic causes
This study follows adults with suspected or confirmed melorheostosis to understand how the condition develops and what outcomes to expect. It may help researchers better understand the disease and its genetic factors.
Bethesda, MarylandAges 18–90 - NCT02257866Recruiting
Study of blood vessel inflammation over time
This study looks at different types of blood vessel inflammation (vasculitis) to learn more about why they happen and how they progress. By joining, you may help doctors better understand these conditions and improve future treatments.
Bethesda, MarylandAges 3 years+ - NCT01631617RecruitingPhase 2
Atopic dermatitis treatments and how they affect skin
This Phase 2 study tests different treatments for atopic dermatitis (eczema) by looking at changes in skin health. It may help people find safer, more effective ways to control moderate to severe eczema and related skin infections.
Bethesda, MarylandAges 2–50 - NCT01422694Recruiting
Understanding spondyloarthritis over time
This study follows people with spondyloarthritis (an inflammatory arthritis that often affects the spine and joints) and their family members over time to better understand how the disease develops and progresses. It also includes a research stool sample test to learn about gut bacteria.
Bethesda, MarylandAges 2–99 - NCT00051857Recruiting
MRI Study of Muscle and Bone Function
This research study uses MRI scans (a safe imaging tool) to understand how bones, muscles, and joints work. Researchers are looking for both people with muscle or bone injuries and healthy volunteers to compare how the body moves and functions.
Bethesda, MarylandAges 5–95 - NCT00001372Recruiting
Understanding Lupus: Research Study at NIH
This research study aims to better understand systemic lupus erythematosus (SLE), an autoimmune disease where the body's immune system attacks its own tissues. Researchers will evaluate patients with lupus, study genetic factors, and perform optional imaging tests to learn how the disease affects blood vessels and the heart.
Bethesda, MarylandAges 3–120 - NCT00024479Recruiting
Understanding how rheumatic diseases develop over time
This research study follows people with known or suspected rheumatic diseases (like arthritis, lupus, or similar conditions) to learn how these conditions change and progress naturally. By tracking your health over time, researchers hope to better understand these diseases and improve treatments.
Bethesda, MarylandAges 18–100
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Common questions
- Are there clinical trials for musculoskeletal?
- Yes. Clin2 currently lists 208 recruiting musculoskeletal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.