Clinical trials
Chronic Musculoskeletal Pain clinical trials
Below are recruiting chronic musculoskeletal pain clinical trials, each written for real people, not researchers. We’re tracking 120 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06004804Recruiting
Psychological treatments for chronic pain in veterans
This study compares two group psychological treatments for chronic pain delivered over video conference. It aims to see if these treatments help reduce pain and improve quality of life for veterans.
West Los Angeles, CaliforniaAges 60–95 - NCT07218757Recruiting
Trial of emotional awareness therapy for veterans with chronic pain
This study tests if a type of therapy that helps you understand and express emotions related to pain (called Emotional Awareness and Expression Therapy) can reduce chronic pain in veterans. It is designed for veterans who have had muscle or joint pain for at least 3 months and rate their pain as moderate or greater.
Los Angeles, CaliforniaAges 18 years+ - NCT06870162Recruiting
Pain disengagement training: a writing study for chronic pain
This study tests a writing-based program to help people with chronic pain learn to disengage from pain-related thoughts. It aims to reduce pain catastrophizing and improve daily function.
Boston, MassachusettsAges 18 years+ - NCT07756229Recruiting
Physiotherapy for long-term neck pain
This study looks at how physiotherapy affects brain activity and symptoms in people with chronic neck pain lasting more than 3 months. It aims to see if physiotherapy can help reduce pain and improve function.
San Sebastián, GuipuzcoaAges 18 years+ - NCT07630350Enrolling by invitation
Virtual Reality for Young People With Chronic Pain
This study tests whether wearing virtual reality goggles can help young people (ages 7–21) manage chronic pain in their neck, shoulders, or arms. Researchers want to see if VR activities can reduce pain and improve daily life.
Allison Park, PennsylvaniaAges 7–21 - NCT06535633Recruiting
Exercise program for older adults with chronic pain
This study looks at whether a community exercise program can help older adults with long-term muscle or joint pain. It is designed for people who are not already active and want to try a gentle, guided exercise program.
LimerickAges 50 years+ - NCT07001449Recruiting
Pain education for chronic muscle or joint pain
This study tests a type of pain education that focuses on communication to help people with long-term muscle or joint pain. It aims to see if learning about pain in a new way can help reduce symptoms and improve quality of life.
Lamia, Central GreeceAges 18–65 - NCT06709963Recruiting
Brain stimulation for older adults with chronic back or knee pain
This study tests a type of brain stimulation called intermittent theta burst stimulation to see if it can reduce pain and improve thinking in older adults with long-term back or knee pain. The treatment involves a non-invasive procedure that uses magnetic pulses to stimulate the brain.
Hong KongAges 60–85 - NCT06175884Recruiting
Communication skills for chronic muscle and joint pain
This trial tests how a physical therapist's communication style affects pain and function in people with long-term muscle or joint pain. Participants will fill out questionnaires and watch a video to see if better communication improves outcomes.
LamiaAges 18–65 - NCT06509087Recruiting
Combining CT and MRI for joint pain procedure
This study tests a procedure called transarterial microembolization for chronic shoulder or knee pain that hasn't improved with other treatments. It uses both CT and MRI to guide the procedure and see if it can help reduce pain.
TaipeiAges 20–80 - NCT07732062Recruiting
Emotion-focused therapy for chronic pain patients using medical cannabis
This study tests a new type of talking therapy (vEAET-H) to see if it helps people with chronic pain who are already using medical cannabis. The goal is to find out if adding this therapy can improve pain and well-being.
Tel AvivAges 18 years+ - NCT05700682Recruiting
MRI-guided artery blockage procedure for long-term joint pain
This study tests whether an MRI scan that looks at blood flow can help target a joint embolization procedure to reduce chronic shoulder, hip, or knee pain. It first uses MRI to find signs of increased blood flow, then may use the findings to guide treatment if you qualify.
Palo Alto, CaliforniaAges 25–80 - NCT05701982Recruiting
Walking plus Tai Chi coach via video for COPD and pain
This study tests whether a phone/computer program that combines walking training with Tai Chi improves physical function (how well you move) in people who have COPD and long-term body or muscle pain. It may help you build strength, balance, and safer movement—especially if pain makes activity hard.
Boston, MassachusettsAges 40–100 - NCT05752396Recruiting
Study of Pain Patterns Over Time in Kids
This study follows kids who have a specific type of chronic pain (headaches, stomach pain, or muscle/joint pain) to better understand how pain changes over time. It also checks whether certain factors are linked to those pain patterns.
Cincinnati, OhioAges 10–19 - NCT05953155Recruiting
Yoga for chronic back pain with a poorer outlook
This trial studies whether a yoga program can reduce symptoms and improve function for people with long-lasting, non-specific back pain and a poorer prognosis. You may be eligible if your back pain has lasted at least 3 months and you meet certain pain and questionnaire scores.
Belo Horizonte, Minas GeraisAges 18–60 - NCT05963607Recruiting
Weighted blanket trial to reduce chronic pain
This study tests whether using a 15-pound weighted blanket can lower pain and improve sleep for Veterans with long-lasting, non-cancer musculoskeletal pain. It may help by reducing discomfort during rest and sleep.
San Diego, CaliforniaAges 18 years+ - NCT06058624Recruiting
Digital pain management program for veterans
This study tests a new digital program that helps veterans with long-term pain learn to accept and cope with it. You would use a computer at home to complete the program and share your feedback.
West Haven, ConnecticutAges 18 years+ - NCT06119698Recruiting
Improving Health for Older Adults With Pain Through Engagement
This study tests a program to help older adults with long-lasting bone, joint, or muscle pain become more active. Participants wear a smartwatch and get support to manage their pain and improve their health.
Boston, MassachusettsAges 55 years+ - NCT06297447Recruiting
Keeping it Simple: rehab for chronic pain
This study looks at how to better help people with ongoing muscle or joint pain who are getting rehabilitation through their local municipality. The goal is to learn what works best for you.
Holbæk, Region SjællandAges 18 years+ - NCT06311240Recruiting
Chronic pain therapy in hemodialysis patients
This study looks at whether a certain kind of therapy can help people on dialysis who have chronic pain. If you have kidney failure and have been on hemodialysis for at least 3 months, you may be able to join.
Terrassa, BarcelonaAges 18 years+ - NCT06395428RecruitingPhase 4
Haloperidol for severe back pain in the ER
This study tests whether the medication haloperidol, given in the emergency room, can help relieve severe back pain that started on its own (not from an injury). It compares haloperidol to a common pain reliever called ketorolac.
Kalamazoo, MichiganAges 18–65 - NCT06500780Recruiting
Pain and depression support for African Americans
This study tests a program that helps people with both long-term pain and depression. It includes coaching and support to help you feel better and manage your health. The study is for Black or African American adults.
Indianapolis, IndianaAges 18 years+ - NCT06512727Recruiting
Pain management study for Black older adults with long-term joint pain
This study tests two different approaches to help Black adults aged 50–92 manage chronic muscle or joint pain in their hips, knees, lower back, or ankles. It aims to find which method works better to reduce pain and improve daily life.
Gainesville, FloridaAges 50–92 - NCT06515925Recruiting
Virtual group program for managing chronic pain
This study tests a virtual group program that combines medical care with integrative approaches like mindfulness and gentle movement to help adults manage chronic musculoskeletal pain.
Malden, MassachusettsAges 18 years+
Hear when a new Chronic Musculoskeletal Pain trial opens
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Common questions
- Are there clinical trials for chronic musculoskeletal pain?
- Yes. Clin2 currently lists 120 recruiting chronic musculoskeletal pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic musculoskeletal pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic musculoskeletal pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.