Clinical trials
Musculoskeletal Diseases or Conditions clinical trials
Below are recruiting musculoskeletal diseases or conditions clinical trials, each written for real people, not researchers. We’re tracking 4,065 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05998694Recruiting
Monitoring a new aortic heart valve for safety and effectiveness
This trial tests how well a new replacement heart valve works and how safe it is. You might qualify if you need a planned first-time aortic valve replacement and are 60-70 years old (or younger if you cannot take blood thinners).
Kemerovo, Kemerovo OblastAges 60–70 - NCT06003855Recruiting
Oxygen-guided walking therapy for leg pain
This study tests if monitoring oxygen levels during supervised walking therapy helps people with leg pain from narrowed arteries. It may improve how far you can walk without pain.
Omaha, NebraskaAges Any age - NCT06005818RecruitingPhase 2
MRD-guided therapy for kidney cancer after surgery
This trial tests whether personalized monitoring of cancer DNA in your blood (MRD) can guide treatment decisions after kidney cancer surgery. If MRD is detected, you may receive extra immunotherapy to reduce the risk of cancer returning.
Birmingham, AlabamaAges 18 years+ - NCT06006637Recruiting
Measuring and reducing autism symptoms
This study tests a new platform designed to measure and reduce autism symptoms in children ages 2 to 8. It may help if your child has an autism diagnosis and is not taking psychiatric medications.
New York, New YorkAges 2–8 - NCT06013865RecruitingPhase 4
Empagliflozin for kidney transplant recipients
This trial tests if empagliflozin, a diabetes medicine that also protects the kidneys, can help people who have received a kidney transplant. It may be an option if you have reduced kidney function or diabetes after transplant.
Hines, IllinoisAges 19 years+ - NCT06013956RecruitingPhase 4
Personalized deep brain stimulation for Parkinson's
This study tests a personalized way to adjust deep brain stimulation (DBS) therapy in real time for people with Parkinson's disease. It aims to improve how DBS works by tailoring it to each person's needs.
Cleveland, OhioAges 18–80 - NCT06014424RecruitingPhase 2
CBD medication study for agitation in Alzheimer's
This study tests if a CBD medication can help reduce agitation in people with Alzheimer's disease. It's for adults 55 and older who have significant agitation and mild to moderate dementia.
Calgary, AlbertaAges 55 years+ - NCT06014515RecruitingEarly Phase 1
Single injection PET scan to study body metabolism
This study uses a single injection and a special type of PET scan to look at how your body's tissues use fuel (metabolism). It helps researchers learn more about normal and disease-related changes in the heart, liver, and other organs.
Sacramento, CaliforniaAges 18 years+ - NCT06017869RecruitingPhase 2
Mitochondria therapy for Pearson Syndrome in children
This trial tests a one-time infusion of your own blood cells mixed with donated mitochondria to see if it can help children with Pearson Syndrome grow better and improve their health. It is a new approach that aims to provide the energy your cells need.
Ramat Gan, IsraelAges 1–18 - NCT06024421RecruitingPhase 1
Testing high doses of favipiravir in healthy volunteers
This study tests the safety and how the body processes very high doses of the antiviral drug favipiravir in healthy people. It helps find the highest dose that is still safe before testing in patients.
ParisAges 18–75 - NCT06027294Recruiting
Blood flow and muscle function study for stroke survivors
This study looks at how blood flow affects muscle function after a stroke. It may help researchers understand recovery better and find new ways to improve movement.
Milwaukee, WisconsinAges 18–85 - NCT06029049RecruitingPhase 4
Comparing two muscle relaxants for faster breathing tube placement
This study tests two different muscle relaxant drugs—rocuronium and succinylcholine—to see which one helps doctors place a breathing tube faster during emergency anesthesia. It may be a good fit for people who need general anesthesia for surgery and have either a high body mass index or a difficult airway.
Houston, TexasAges 18 years+ - NCT06028828RecruitingPhase 2
Adapted conditioning for stem cell transplant
This trial tests a risk-adapted conditioning regimen (chemotherapy and/or radiation given before transplant) for people with certain blood cancers or bone marrow disorders who need a stem cell transplant from a donor. The goal is to tailor the conditioning strength to each patient’s risk, which may help improve outcomes and reduce side effects.
Orange, CaliforniaAges 18–70 - NCT06029348Recruiting
Brain health and resilience in middle age
This study looks at how well the brain's blood vessels work in midlife. It involves two visits to the University of Pittsburgh and includes an MRI and a mental math test.
Pittsburgh, PennsylvaniaAges 40–59 - NCT06038630RecruitingPhase 2
Xenon gas MRI study for lung and heart health
This study uses a special MRI scan (Xenon gas imaging) to look at how well your lungs and heart are working. It is for people with certain lung conditions, those getting blood transfusions or phlebotomy, or healthy volunteers.
Durham, North CarolinaAges 18 years+ - NCT06041620Recruiting
Gene-edited stem cell therapy for beta-thalassemia
This trial tests a new treatment that uses your own blood stem cells, edited with CRISPR technology, to reduce or eliminate the need for blood transfusions in people with beta-thalassemia.
Tianjin, Tianjin MunicipalityAges 3–35 - NCT06044077RecruitingPhase 3
Testing a new pneumonia vaccine in healthy people
This trial tests a new 23-valent pneumococcal vaccine to see if it safely protects healthy people against pneumonia and other infections caused by pneumococcal bacteria.
Chengdu, SichuanAges 2 years+ - NCT06044571Recruiting
Weight loss program for older adults via telehealth
This trial tests a weight loss program delivered through video calls to help adults aged 65-85 with obesity lose weight. It is designed for those with at least two other health conditions and who are ready to make changes.
Chapel Hill, North CarolinaAges 65–85 - NCT06044935Recruiting
Nicotinamide riboside for fat burning and metabolism
This study tests whether a supplement called nicotinamide riboside (a form of vitamin B3) helps the body burn fat more efficiently during exercise. It may be a good option if you are overweight or have a specific type of diabetes (MODY2) and want to see if a natural supplement can boost your metabolism.
Bethesda, MarylandAges 18–65 - NCT06052280Recruiting
Parkinson's physical therapy: in clinic vs. at home
This study compares in-person physical therapy with a home exercise program you can do using a computer or tablet. It aims to see if remote therapy works as well as coming to the clinic, which could make it easier for you to get the help you need.
CuneoAges 18 years+ - NCT06052501Recruiting
3D lip support study for full-arch implant teeth
This study uses 3D imaging to see how well your lips are supported after getting a full set of implant-supported teeth in your upper jaw. It may help improve future dental restorations for better appearance and function.
LisbonAges Any age - NCT06052969Recruiting
Pulse NanoMED MicroBeads after clot removal for stroke
This trial tests a new treatment called Pulse NanoMED MicroBeads for people who still have a blocked brain artery after a standard clot removal procedure (mechanical thrombectomy). The goal is to see if these tiny beads can clear the remaining blockage and improve blood flow to the brain.
Columbia, South CarolinaAges 18–85 - NCT06053619Recruiting
Virtual reality walking rehab for stroke patients who cannot walk
This trial tests whether adding virtual reality to robot-assisted walking therapy helps people who have had a stroke and cannot walk. It is for patients who had a first stroke in the past 15 days to 6 months.
LimogesAges 35–75 - NCT06055452RecruitingPhase 4
SGLT2 Inhibitors for Pre-Heart Failure with Hypertension
This trial tests if a medicine (SGLT2 inhibitor) given to people with high blood pressure and early signs of heart stress can help prevent heart failure. You may join if your blood pressure is controlled but tests show your heart is beginning to struggle.
Beijing, Beijing MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for musculoskeletal diseases or conditions?
- Yes. Clin2 currently lists 4,065 recruiting musculoskeletal diseases or conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal diseases or conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal diseases or conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.