Clinical trials
Musculoskeletal Diseases or Conditions clinical trials
Below are recruiting musculoskeletal diseases or conditions clinical trials, each written for real people, not researchers. We’re tracking 4,026 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Gilbert, ArizonaAges 18 years+ - NCT02791854Enrolling by invitation
Improving Care for Adults With Crohn’s or Ulcerative Colitis
This trial looks at ways to improve care for adults living with inflammatory bowel disease, including Crohn’s disease and ulcerative colitis. You may be invited if your clinic is part of an inflammatory bowel disease care network called IBD Qorus.
Los Angeles, CaliforniaAges 18–99 - NCT01852370Enrolling by invitationPhase 1/Phase 2
Lung and bone marrow transplant plan for immune system disorders
This early-phase study tests a step-by-step transplant approach: first replacing the lungs, then doing a bone marrow (stem cell) transplant to treat certain immune deficiency diseases. It may help people whose immune problem has led to severe, end-stage lung disease.
Pittsburgh, PennsylvaniaAges 5–45 - NCT01440218Enrolling by invitation
Study for rare illnesses and treatment reactions in families
This trial looks for answers in rare illnesses that either have no known cause or have not improved with usual treatments. It also studies rare harmful reactions that happen after medicines, vaccines, or medical devices, and may involve family members of the affected person.
La Jolla, CaliforniaAges Any age - NCT00001539Recruiting
Lyme disease study's treatment and recovery health
This study looks at the health of people who have had Lyme disease, including those with ongoing symptoms after treatment, and those who have recovered or never had it. It aims to understand the disease and find better ways to manage it.
Bethesda, MarylandAges 13–99 - NCT00344188Recruiting
Study of Leishmania infections
This trial studies people with Leishmania infections (a parasitic disease often from sand fly bites). Researchers aim to better understand and treat the infection, and you may benefit from expert care.
Bethesda, MarylandAges 3–100 - NCT00004568Recruiting
Study of inherited neurological conditions
This study is looking at people with inherited (genetic) neurological conditions, as well as their family members, to better understand these diseases. Participants will receive a thorough evaluation, which may help with diagnosis and research.
Bethesda, MarylandAges 2–120 - NCT00001971Recruiting
Evaluation of patients with liver disease
This research study evaluates people with liver disease or at risk for liver disease, and compares them with healthy volunteers. The goal is to better understand liver disease and improve how doctors diagnose and treat it.
Bethesda, MarylandAges 2–100 - NCT00001979Recruiting
Understanding Immune System Kidney Disease
This research study looks at kidney diseases caused by the immune system—conditions where your body's defense system mistakenly attacks the kidneys. Researchers will study your medical history, blood, and urine to better understand these diseases and potentially improve treatment.
Bethesda, MarylandAges 10–99 - NCT00977977RecruitingPhase 2
Rituximab plus cyclosporine for membranous kidney disease
This trial tests whether rituximab (an immune-targeting medicine) plus cyclosporine (another immune medicine) can better control protein leakage in the urine for people with idiopathic membranous nephropathy. It may help reduce long-lasting kidney damage risk when standard treatments like ACE inhibitor or ARB don’t control the protein level.
Bethesda, MarylandAges 18–90 - NCT00794352Recruiting
Studying immune brain and nerve conditions with tests and samples
This study looks at how immune-related brain or spinal cord illness shows up using exams, MRI scans, and sometimes a spinal fluid test (lumbar puncture), plus collected blood and other samples. It may help researchers better understand these conditions and improve future diagnosis or treatments.
Bethesda, MarylandAges 1 month–99 years - NCT04374721Recruiting
Circadian rhythm genes in adrenal and cortisol disorders
This study looks at how your body's internal clock genes may be affected by adrenal problems or Cushing's syndrome, and how they might change with treatment. It aims to better understand these conditions and potentially improve care.
Roma, RomaAges 18–80 - NCT04774536RecruitingPhase 1/Phase 2
CRISPR gene-edited bone marrow transplant for severe sickle cell
This Phase 1/2 study tests a CRISPR-edited bone marrow (stem cell) transplant to treat severe sickle cell disease. It aims to reduce dangerous sickle-related complications by changing the patient’s stem cells before transplant.
Davis, CaliforniaAges 12–35 - NCT07867184Enrolling by invitation
Firefighter lung health study
This study looks at how firefighting affects your lungs over time. By tracking your health and exposures, researchers hope to find ways to prevent lung problems in firefighters.
Bethesda, MarylandAges 18–65 - NCT07822334RecruitingPhase 1/Phase 2
Study of an investigational drug for chronic obstructive pulmonary disease
This study tests an experimental medication for chronic obstructive pulmonary disease (COPD) in two parts: first in healthy volunteers, then in people with COPD. It aims to see if the drug is safe and how well it works.
Wythenshawe, Greater ManchesterAges 18–80 - NCT07262983RecruitingPhase 1
Baricitinib for Job syndrome with lupus or eczema
This study tests if baricitinib, a pill that changes how your immune system works, is safe and tolerable for people with Job syndrome who also have lupus-like disease or severe eczema. It might offer a new treatment option for these skin and immune problems.
Bethesda, MarylandAges 12–120 - NCT07169630RecruitingPhase 1
PET scan study for Alzheimer's or mild cognitive impairment
This study uses a special PET scan to look at a brain protein called PDE4 in people with Alzheimer's disease or mild cognitive impairment. It may help researchers understand how this protein is involved in memory and thinking problems.
Bethesda, MarylandAges 50–100 - NCT07611578Recruiting
Dual task training for confidence in Parkinson's disease
This study tests a training program that combines physical tasks with thinking challenges (dual tasking). It may help people with Parkinson's feel more confident in their daily activities and improve their quality of life.
Santiago, Las CondesAges 18 years+ - NCT05003947RecruitingPhase 1
Stem cell infusion for Crohn’s or ulcerative colitis safety
This Phase 1 trial tests whether an IV infusion of donated (allogeneic) stem cells is safe in people with Crohn’s disease or ulcerative colitis. It focuses mainly on safety and tolerability, and it may offer a new treatment approach if you qualify.
Naples, FloridaAges Any age - NCT06831032Recruiting
Adaptive radiation for prostate cancer in lymph nodes
This trial tests a type of targeted radiation (SBRT) for prostate cancer that has come back only in certain lymph nodes around the belly or hip. The goal is to see if adapting the radiation plan during treatment can make the response last longer.
Toronto, OntarioAges 18 years+ - NCT03394365RecruitingPhase 3
Study of tabelecleucel for transplant patients with EBV-related lymphoma
This trial tests an investigational treatment called tabelecleucel for people who developed a type of lymphoma after an organ or stem cell transplant. The lymphoma is caused by the Epstein-Barr virus (EBV) and has not responded to standard therapy with rituximab or chemotherapy. Tabelecleucel uses special immune cells to fight the virus and the cancer.
Duarte, CaliforniaAges Any age - NCT07880275Recruiting
Memory disorders research study
This study collects health information and samples from people with memory problems and from healthy younger adults to better understand memory disorders. Participating may help researchers learn more about these conditions.
Seoul, Seodamun-guAges 19 years+ - NCT07880379RecruitingPhase 1
Brain scan for Parkinson's disease
This trial tests a new brain scan that may show a protein linked to Parkinson's disease. It could help doctors see the disease better and might lead to earlier diagnosis and better treatment.
New Haven, ConnecticutAges 40–80 - NCT07881627Recruiting
Amino acid nutrition during dialysis for malnutrition and anemia
This trial is testing whether giving a special amino acid solution during dialysis can improve nutrition in people with kidney disease who are on dialysis and also have malnutrition and anemia. Amino acids are the building blocks of protein, and this may help you gain strength and improve your overall health.
Bangli, BaliAges 18 years+
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Common questions
- Are there clinical trials for musculoskeletal diseases or conditions?
- Yes. Clin2 currently lists 4,026 recruiting musculoskeletal diseases or conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a musculoskeletal diseases or conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a musculoskeletal diseases or conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.