Lung and bone marrow transplant plan for immune system disorders
Part of Blood & lymphatic, Genetic & congenital, Hormones & metabolism, Immune system & allergy clinical trials.
This early-phase study tests a step-by-step transplant approach: first replacing the lungs, then doing a bone marrow (stem cell) transplant to treat certain immune deficiency diseases. It may help people whose immune problem has led to severe, end-stage lung disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You (or your parent/guardian) must be able and willing to understand the study and sign consent forms.
- Age 5 to 45 years at the time you sign consent.
- You must have a known immune system disorder where a bone marrow transplant is medically recommended.
- Your lung disease must be advanced enough that the lung transplant team says you are a candidate for a lung transplant in both lungs.
- Your heart, liver, and kidney results must meet the study’s thresholds (kidney function, liver enzymes, bilirubin, and heart pumping strength).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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