Clinical trials
Myofascial Pain clinical trials
Below are recruiting myofascial pain clinical trials, each written for real people, not researchers. We’re tracking 79 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07573527Recruiting
Online therapy for upper back muscle pain from trigger points
This study tests whether remote physical therapy (done online) can help relieve neck and upper back pain caused by tight knots in your rhomboid muscles. You would receive guided exercises and treatment through video calls instead of visiting a clinic in person.
Karachi, SindhAges 18–35 - NCT07692126Recruiting
Neck pain and hand strength: core vs shoulder exercises
This study compares two types of exercises to see which better improves hand grip strength and neck pain. If you have had chronic myofascial neck pain (trigger points) in the upper shoulder muscle for over 6 months, this trial may help find which exercise works best for you.
Giza, Giza GovernorateAges 25–45 - NCT07278570Recruiting
Tracking muscle stiffness with MRI during hands-on therapy for low back pain
This study uses a special MRI scan to see if hands-on therapy (manual therapy) helps reduce muscle stiffness and pain in people with chronic low back pain. It aims to find a better way to measure how well this treatment works.
Rochester, MinnesotaAges 18 years+ - NCT07694882Recruiting
Gentle pressure techniques for chronic neck pain
This study tests two different types of gentle pressure techniques (myofascial release) to see which one helps relieve long-term neck pain and improve everyday function. It is for people with chronic neck pain that isn't caused by a specific injury or disease.
Famagusta, HatayAges 18–45 - NCT04704297RecruitingPhase 4
Trigger point shots for low back muscle pain
This trial tests whether injecting sore “trigger points” in low back muscles helps improve chronic low back pain. It compares treatments in people with specific low back muscle pain patterns and excludes several other causes of pain.
Tacoma, WashingtonAges 18 years+ - NCT05851326Recruiting
Ultrasound and gentle stimulation for stubborn muscle pain
This trial tests whether low-energy ultrasound and electrical/magnetic stimulation can reduce long-lasting myofascial pain in the low back, neck, or tension-type headaches. It may help if your pain has lasted at least 3 months and is still noticeable despite your current treatment plan.
GrazAges 18–99 - NCT07494162Recruiting
Acupuncture for chronic low back pain with muscle knots
This trial tests if acupuncture can help chronic low back pain by looking at changes in muscle metabolism and blood flow. It compares real acupuncture with a sham (fake) procedure to see if there is a true benefit.
Sacramento, CaliforniaAges 18 years+ - NCT07547605RecruitingPhase 4
Comparing PRP, Steroid, and Combined Injections for Neck and Shoulder Pain
This study tests three different injection treatments for upper trapezius myofascial pain (a specific type of muscle knot in your neck/shoulder area). Researchers will compare platelet-rich plasma (PRP, made from your own blood), a steroid injection, and a combination of both to see which works best for pain relief.
Kyrenia, KeryneiaAges 18–65 - NCT07469345Enrolling by invitation
Teeth Grinding and Pelvic Pain in Young Men
This study looks at how teeth grinding (bruxism) is linked to pelvic pain, erectile function, and anxiety in young adult men. It aims to understand if these issues are connected, which could help develop better treatments.
KonyaAges 18–30 - NCT05604066Enrolling by invitation
MRI scan to study muscle pain stiffness in low back or leg
This study uses a special MRI scan (magnetic resonance elastography) to measure how stiff muscles are in people with long-lasting low back or leg muscle pain. It may help researchers better understand myofascial pain—pain caused by tight, tender spots in muscle.
Rochester, MinnesotaAges 18 years+ - NCT06892041Recruiting
MRI study for jaw muscle pain
This trial uses a special MRI scan to measure jaw muscle pain. It aims to better understand this condition and may help improve future treatments.
New York, New YorkAges 18–65 - NCT07490366Recruiting
Exercise vs needle treatment for shoulder muscle pain
This study compares three treatments for long-term shoulder muscle pain: exercises, dry needling (tiny needles into tight muscle spots), and a numbing shot between muscle layers. It aims to find which works best for myofascial pain syndrome.
Istanbul, IstanbulAges 18–55 - NCT05972837Recruiting
Home electrical stimulation for long-lasting neck muscle pain
This trial studies whether a home-based electrical stimulation device placed on the neck can reduce pain for people with long-lasting neck muscle pain. It may help if your pain has lasted at least 2 months and is moderate to severe.
New Taipei CityAges 20–60 - NCT07689396Recruiting
What affects treatment expectations for muscle pain?
This study tests how your expectations about treatment affect your recovery from myofascial pain (a type of muscle pain with tender spots). You will be in physical therapy and answer questions about your pain and outlook.
KonyaAges 18 years+ - NCT07511751Recruiting
Comparing treatments for myofascial pain syndrome
This trial compares three different treatments to find which works best for long-term back pain caused by myofascial pain syndrome, a condition where tight muscle knots cause pain. It is for people who have not found relief with standard treatments.
Adapazarı, SakaryaAges 18–65 - NCT05354869Recruiting
Electrical stimulation therapy for pelvic floor muscle pain
This trial tests a treatment that uses gentle electrical stimulation through the vagina to reduce long-term pelvic pain caused by tight pelvic floor muscles. You might join if your pain has lasted over 6 months and exam shows specific muscle “trigger points.”
Los Angeles, CaliforniaAges 18–65 - NCT07322445Recruiting
Study of neck and shoulder pain with special MRI
This study uses special MRI scans to look at muscles and nerves in people with long-term neck or shoulder pain caused by trigger points (tender spots in muscles). The goal is to understand what happens in the body with this type of pain—so doctors can find better ways to treat it.
St Louis, MissouriAges 18–80 - NCT07098754Recruiting
Physical therapy for neck pain and posture improvement
This study compares different physical therapy techniques to improve neck posture and reduce pain in people with myofascial pain syndrome. It may help if you have mild to moderate neck pain from muscle knots and are open to physiotherapy.
Bahawalpur, Punjab ProvinceAges 20–40 - NCT07119255Recruiting
PRP acupuncture for long-term neck pain from muscle tightness
This study tests whether a treatment called platelet-rich plasma (PRP) acupuncture — using your own blood proteins — can reduce chronic neck pain caused by a common muscle condition. It may be a good option if you have had neck pain for months and want a non-surgical approach.
JakartaAges 18–59 - NCT07181447Recruiting
Light test for muscle-based pelvic pain
This study uses a light device on the skin to detect muscle trigger points in women with long-term pelvic pain. The goal is to see if near-infrared spectroscopy (NIRS) can help diagnose myofascial pelvic pain more easily.
Los Angeles, CaliforniaAges 18 years+ - NCT04732507Enrolling by invitationPhase 2
Trigger point injections: test fewer needlings for pain relief
This Phase 2 study tests whether doing a smaller number of needle “treatments” during trigger point injections works as well for myofascial pain. If you’ve tried safer treatments without success (or can’t do physical therapy), you may be eligible to help answer the best treatment approach.
Tucson, ArizonaAges 18 years+ - NCT06338514Recruiting
Dry needling for upper back muscle pain
This study tests if dry needling helps reduce shoulder pain caused by muscle knots in the upper back. It may be an option if you have not had recent back surgery or treatments.
KütahyaAges 18–80 - NCT07685340Recruiting
Cupping vs Massage Tool for Chronic Low Back Pain
This trial tests two hands-on therapies—dry cupping and a special massage technique—to see which works better for long-term low back pain caused by muscle knots. You may be able to join if your pain has lasted over 3 months and you have trigger points.
Rawalpindi, Punjab ProvinceAges 25–45 - NCT06492148Recruiting
Myofascial Release for Period Pain in Women
This study tests a gentle hands-on technique called myofascial release to see if it can reduce period pain in women who have primary dysmenorrhea (painful periods without an underlying condition). If you have moderate to severe cramps and don't use hormonal birth control, you may be able to join.
AnkaraAges 18–35
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Common questions
- Are there clinical trials for myofascial pain?
- Yes. Clin2 currently lists 79 recruiting myofascial pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a myofascial pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a myofascial pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.