Clinical trials
Myofascial Pain Syndrome clinical trials
Below are recruiting myofascial pain syndrome clinical trials, each written for real people, not researchers. We’re tracking 47 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07058636Recruiting
Nerve block plus trigger point shots for neck pain relief
This study tests if adding a nerve block to standard trigger point injections provides better relief for people with chronic neck pain caused by myofascial pain syndrome.
AnkaraAges 18–65 - NCT06982456Enrolling by invitation
Manual therapy for neck pain in physiotherapy students
This study tests if manual therapy techniques help students with localized neck pain feel better. It focuses on pain in the upper shoulder muscle.
MurciaAges 18–40 - NCT06892041Recruiting
MRI study for jaw muscle pain
This trial uses a special MRI scan to measure jaw muscle pain. It aims to better understand this condition and may help improve future treatments.
New York, New YorkAges 18–65 - NCT06807177Enrolling by invitation
Collagen injections for chronic neck pain
This trial tests if collagen injections into the neck can reduce chronic muscle pain and whether certain blood markers can show how well the treatment works. It may help if you have had neck pain for more than 12 weeks.
WarsawAges 18–65 - NCT06338488Recruiting
Dry needling for shoulder pain from muscle knots
This trial tests if dry needling (inserting thin needles into muscle knots) can reduce shoulder pain caused by a condition called myofascial pain syndrome. It may help if you have a specific muscle knot in your shoulder blade area and significant pain.
Kütahya, TürkiyeAges 18–80 - NCT06338514Recruiting
Dry needling for upper back muscle pain
This study tests if dry needling helps reduce shoulder pain caused by muscle knots in the upper back. It may be an option if you have not had recent back surgery or treatments.
KütahyaAges 18–80 - NCT05851326Recruiting
Ultrasound and gentle stimulation for stubborn muscle pain
This trial tests whether low-energy ultrasound and electrical/magnetic stimulation can reduce long-lasting myofascial pain in the low back, neck, or tension-type headaches. It may help if your pain has lasted at least 3 months and is still noticeable despite your current treatment plan.
GrazAges 18–99 - NCT07496099Recruiting
Comparing two muscle-release therapies for low back pain
This study compares two types of gentle muscle-release techniques—post-isometric relaxation and myofascial release—to see which better relieves low back pain caused by lower cross syndrome, a common muscle imbalance. If you have ongoing back pain and tight hamstrings, this trial may offer a drug-free treatment option.
Karachi, SindhAges 18–45 - NCT07322445Recruiting
Study of neck and shoulder pain with special MRI
This study uses special MRI scans to look at muscles and nerves in people with long-term neck or shoulder pain caused by trigger points (tender spots in muscles). The goal is to understand what happens in the body with this type of pain—so doctors can find better ways to treat it.
St Louis, MissouriAges 18–80 - NCT06991387Recruiting
Myofascial release for text neck pain
This study tests a hands-on therapy called myofascial release to see if it can quickly ease neck pain and related symptoms from 'text neck' (pain from using devices too much). If you are a young adult who spends a lot of time on your phone and has neck pain, you might be a good fit.
Karabük, Karabük ProvinceAges 18–40 - NCT07525921Recruiting
Dry Needling for Calf Pain in Amateur Football Players
This study tests whether dry needling—inserting thin needles into tight muscle knots in the calf—can reduce pain and improve running speed and performance in young football players. Researchers want to see if this treatment helps athletes play better and feel less discomfort.
Islamabad, Punjab ProvinceAges 18–25 - NCT07390851Recruiting
Magnesium with lidocaine for jaw and neck muscle trigger points
This trial tests whether adding magnesium to lidocaine makes trigger point injections more effective for jaw, face, or upper shoulder pain. The results will be measured by pain scales and muscle activity tests.
Giza, Giza GovernorateAges 18–70 - NCT06492148Recruiting
Myofascial Release for Period Pain in Women
This study tests a gentle hands-on technique called myofascial release to see if it can reduce period pain in women who have primary dysmenorrhea (painful periods without an underlying condition). If you have moderate to severe cramps and don't use hormonal birth control, you may be able to join.
AnkaraAges 18–35 - NCT07444112Recruiting
Myofascial release for text neck in university students
This trial tests if a hands-on therapy called myofascial release can help university students with text neck (neck pain from looking down at phones). It aims to reduce pain and improve neck function.
Lahore, Punjab ProvinceAges 18–30 - NCT07138807Recruiting
Neck exercises for female nurses with neck pain
This study compares two types of neck exercises to see which works better for reducing neck pain and disability in female nurses. You may be able to join if you are a nurse with moderate neck pain and a tender spot in your upper back muscle, and haven't had treatment for it in the past month.
Faisalabad, Punjab ProvinceAges 18–30 - NCT04445545Recruiting
Laser treatment for tight neck trigger points
This trial tests whether high-intensity laser therapy applied to specific “trigger points” in the neck muscles can help people with painful tight spots. You may be eligible if you have those trigger points and meet safety rules about recent neck/shoulder problems and skin and nerve conditions.
Santiago, Las CondesAges 18 years+ - NCT06664359Recruiting
Safer trigger point injections using ultrasound guidance
This study is testing a safer way to give trigger point injections — shots that relieve painful muscle knots — in the upper back. Researchers will use ultrasound to guide the needle and measure how close it is to the lungs, to avoid complications.
AnkaraAges 18–65 - NCT07044869Recruiting
Comparing two hand therapies for piriformis syndrome in women
This study compares two gentle hands-on treatments – a 'facilitated positional release' technique and a 'manual myofascial release' technique – to see which better relieves pain from piriformis syndrome in women.
IslamabadAges 25–50 - NCT06780904Recruiting
Dry needling plus stretching for neck pain relief
This study tests if combining dry needling with gentle stretching or muscle energy techniques works better for treating neck pain caused by muscle knots (trigger points). It aims to find a simple, effective way to reduce pain and improve movement.
Kandy, Central ProvinceAges 18–60 - NCT06718413RecruitingPhase 2
Study on shoulder pain after stroke
This study tests a treatment for shoulder stiffness and pain caused by muscle tightness after a stroke. It focuses on people who still have some limited shoulder movement and may help improve range of motion and comfort.
Baltimore, MarylandAges 18 years+ - NCT07714031Recruiting
Wrist Release Therapy for Overuse Syndrome
This study tests a special hands-on therapy technique for people with wrist pain from overuse, like computer workers. It may help improve movement and reduce pain without surgery.
Faisalabad, Punjab ProvinceAges 20–50 - NCT06753487Recruiting
Comparing two gentle therapies for piriformis syndrome in women
This trial tests two hands-on treatments (Facilitated Positional Release and Manual Myofascial Release) to see which works better for women with piriformis syndrome. If you're a woman aged 25–50 with buttock or hip pain for at least 2 months, this study might help you find relief.
Rawalpindi, Punjab ProvinceAges 25–50 - NCT06754982Recruiting
Timing of pain, stiffness, and function in plantar fasciitis after muscle release
This trial tests whether a hands-on therapy called myofascial release can help with morning pain, stiffness, and walking in people with plantar fasciitis. It aims to see how these symptoms change over time after treatment.
Talca, Maule RegionAges 18–60
Hear when a new Myofascial Pain Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for myofascial pain syndrome?
- Yes. Clin2 currently lists 47 recruiting myofascial pain syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a myofascial pain syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a myofascial pain syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.