Clinical trials
Myofascial Pain clinical trials
Below are recruiting myofascial pain clinical trials, each written for real people, not researchers. We’re tracking 77 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07576244Recruiting
Core exercises and massage therapy for postpartum back pain
This study tests whether core-strengthening exercises combined with a hands-on massage technique called myofascial induction therapy can help reduce back pain after vaginal delivery. It may help you recover faster and manage pain without medication.
Sialkot, Punjab ProvinceAges 20–45 - NCT07138807Recruiting
Neck exercises for female nurses with neck pain
This study compares two types of neck exercises to see which works better for reducing neck pain and disability in female nurses. You may be able to join if you are a nurse with moderate neck pain and a tender spot in your upper back muscle, and haven't had treatment for it in the past month.
Faisalabad, Punjab ProvinceAges 18–30 - NCT04445545Recruiting
Laser treatment for tight neck trigger points
This trial tests whether high-intensity laser therapy applied to specific “trigger points” in the neck muscles can help people with painful tight spots. You may be eligible if you have those trigger points and meet safety rules about recent neck/shoulder problems and skin and nerve conditions.
Santiago, Las CondesAges 18 years+ - NCT07525921Recruiting
Dry Needling for Calf Pain in Amateur Football Players
This study tests whether dry needling—inserting thin needles into tight muscle knots in the calf—can reduce pain and improve running speed and performance in young football players. Researchers want to see if this treatment helps athletes play better and feel less discomfort.
Islamabad, Punjab ProvinceAges 18–25 - NCT07861906Recruiting
Wearable device for jaw muscle pain
This study tests a 24-hour wearable device that tracks jaw muscle activity to better understand and manage chronic jaw muscle pain. You would wear the device for a day to see how your muscles behave, which could help improve future treatments.
Downers Grove, IllinoisAges 18 years+ - NCT07847541RecruitingPhase 2
Botulinum toxin injections for jaw muscle pain
This trial tests whether botulinum toxin (Botox) injections can reduce pain in the jaw muscles for people with temporomandibular joint (TMJ) disorders that haven't improved with other treatments. It may help if you have ongoing jaw pain and muscle tightness.
IslamabadAges 18–60 - NCT06664359Recruiting
Safer trigger point injections using ultrasound guidance
This study is testing a safer way to give trigger point injections — shots that relieve painful muscle knots — in the upper back. Researchers will use ultrasound to guide the needle and measure how close it is to the lungs, to avoid complications.
AnkaraAges 18–65 - NCT07390851Recruiting
Magnesium with lidocaine for jaw and neck muscle trigger points
This trial tests whether adding magnesium to lidocaine makes trigger point injections more effective for jaw, face, or upper shoulder pain. The results will be measured by pain scales and muscle activity tests.
Giza, Giza GovernorateAges 18–70 - NCT07270276Recruiting
Dry needling for shoulder muscle pain
This study tests if dry needling (a therapy that uses thin needles to release muscle knots) can help with shoulder muscle pain. It uses special tests to measure how the treatment affects your muscles and pain.
Boston, MassachusettsAges 18–80 - NCT06316583Recruiting
Dry needling for painful periods study
This trial tests whether dry needling (a type of acupuncture) can help relieve primary dysmenorrhea (painful periods without another cause). It compares the effects on specific acupoints to see which works best.
Beijing, Beijing MunicipalityAges 18–30 - NCT06912438Enrolling by invitation
Emotional release after dry needling for jaw and head pain
This study tests whether a dry needling technique (trigger point needling) can help release emotional tension and reduce pain from muscle knots in the head and neck. It may be a good option if you have jaw or headache pain related to muscle tightness.
Tel Aviv, IsraelAges 18 years+ - NCT07241559Recruiting
Low back pain treatment study: injection and mobilization
This study tests two treatments for chronic low back pain: a special injection of dextrose (a sugar solution) guided by ultrasound, and a technique to mobilize the fascia (connective tissue) in the lower back. It aims to see if these help people who haven't found relief from standard treatments.
Ankara, AltındağAges 18–65 - NCT06696898Recruiting
Stretching with and without muscle release for sciatica
This study tests if adding myofascial release (a type of hands-on therapy for tight muscles) to a standard self-stretching program helps relieve sciatica pain and improve movement. It's for people with long-standing (chronic) one-sided sciatica.
Lahore, Punjab ProvinceAges 25–50 - NCT07496099Recruiting
Comparing two muscle-release therapies for low back pain
This study compares two types of gentle muscle-release techniques—post-isometric relaxation and myofascial release—to see which better relieves low back pain caused by lower cross syndrome, a common muscle imbalance. If you have ongoing back pain and tight hamstrings, this trial may offer a drug-free treatment option.
Karachi, SindhAges 18–45 - NCT06780904Recruiting
Dry needling plus stretching for neck pain relief
This study tests if combining dry needling with gentle stretching or muscle energy techniques works better for treating neck pain caused by muscle knots (trigger points). It aims to find a simple, effective way to reduce pain and improve movement.
Kandy, Central ProvinceAges 18–60 - NCT07027644Recruiting
Combined therapy for chronic neck pain relief
This trial tests whether combining a muscle-relaxation technique with cupping therapy is more effective than either alone for treating chronic neck pain caused by muscle knots in the upper trapezius. Participants must have had these knots for more than 6 months.
GizaAges 18–40 - NCT07347041Recruiting
Trigger point injections for hip osteoarthritis pain
This study tests if injecting pain-relieving medication into tight muscle knots (called trigger points) can reduce hip pain from osteoarthritis. It is for people who still have pain despite trying other treatments.
Beijing, Beijing MunicipalityAges 45 years+ - NCT07347054Recruiting
Trigger point injection for shoulder arthritis pain
This study tests whether injecting a medication into painful knots in the shoulder muscle can reduce pain from shoulder arthritis. It may be a good option if you have had shoulder pain for at least 3 months and other treatments haven't worked well enough.
Beijing, Beijing MunicipalityAges 45 years+ - NCT06875804Recruiting
Compressive release for knee cap tracking in knee pain
This trial tests a hands-on therapy called compressive myofascial release for the muscle on the outside of your thigh. It aims to see if it helps with kneecap tracking problems that cause pain during daily activities.
Lahore, Punjab ProvinceAges 20–40 - NCT07470307Recruiting
Exercise for chronic low back pain: Pilates vs. strength training
This trial compares dynamic lumbar strengthening exercises to Pilates, both combined with myofascial release, for people with ongoing low back pain. It aims to find which approach works better for reducing pain and improving function.
Lahore, Punjab ProvinceAges 25–35 - NCT06718413RecruitingPhase 2
Study on shoulder pain after stroke
This study tests a treatment for shoulder stiffness and pain caused by muscle tightness after a stroke. It focuses on people who still have some limited shoulder movement and may help improve range of motion and comfort.
Baltimore, MarylandAges 18 years+ - NCT07854041Recruiting
Release techniques for kneecap pain
This study tests two hands-on therapies to ease kneecap pain. It may help if your pain has lasted at least three months and gets worse with stairs, running, or sitting for a long time.
Lahore, Punjab ProvinceAges 15–40 - NCT07588087Recruiting
Shoulder Release Therapy for Frozen Shoulder Pain
This study tests whether adding a specific muscle-release technique to shoulder exercises helps reduce pain and improve movement in frozen shoulder (adhesive capsulitis). Frozen shoulder causes stiffness and pain that limits arm movement; this trial explores whether combining two physical therapy methods works better than standard care.
Islamabad, Punjab ProvinceAges 35–70 - NCT07347028Recruiting
Trigger point injections for knee osteoarthritis pain
This trial tests whether injecting medication into muscle knots (trigger points) can reduce knee pain in people with knee osteoarthritis. It may be an option if other treatments haven't helped enough.
Beijing, Beijing MunicipalityAges 45 years+
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Common questions
- Are there clinical trials for myofascial pain?
- Yes. Clin2 currently lists 77 recruiting myofascial pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a myofascial pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a myofascial pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.