Clinical trials
Nervous System Diseases clinical trials
Below are recruiting nervous system diseases clinical trials, each written for real people, not researchers. We’re tracking 264 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07188077Recruiting
Study of immune changes in brain lymphoma
This trial looks at the immune system and metabolism of people with primary central nervous system lymphoma (a type of brain cancer) to find differences that might help with future treatments. It does not test a new drug, but collects samples and medical information.
Fuzhou, FujianAges 18–75 - NCT06446245RecruitingPhase 2
Doxycycline for brain tuberculosis
This trial tests whether adding the antibiotic doxycycline to standard treatment can improve recovery in patients with tuberculosis of the brain (TB meningitis). It may help reduce brain swelling and damage.
Medan, MedanAges 21 years+ - NCT05954845Recruiting
Colonic biopsy study in spinal cord injury gut health
This study looks at how the gut (especially nerve function in the bowel and the gut’s protective lining) works in people with spinal cord injury. It uses planned colonoscopy or rectum/sigmoid exams with small tissue samples to understand whether changes in the gut could contribute to health problems.
NantesAges 18–80 - NCT02979951Recruiting
IV fosfomycin for serious bacterial infections
This trial studies whether IV (through a vein) fosfomycin can treat severe bacterial infections in adults. It may help people whose infection is covered by the standard fosfomycin use and who need hospital-level care.
Hall in TirolAges 18 years+ - NCT07143045Recruiting
Zorifertinib for lung cancer that has spread to the brain
This trial tracks how well zorifertinib works as a first treatment for people with a specific type of advanced lung cancer that has spread to the brain or spinal cord lining. Participants may receive zorifertinib or another standard treatment, and researchers will monitor their response over time.
Hefei, AnhuiAges 18 years+ - NCT05278208RecruitingPhase 1/Phase 2
Lutathera for high-grade brain tumors that returned or got worse
This trial tests if Lutathera, a radioactive drug that targets certain tumors, can help children and young adults with high-grade brain tumors or meningiomas that have come back or are growing. It aims to see if the treatment is safe and works.
Aurora, ColoradoAges 4–39 - NCT04771520RecruitingPhase 2
Avapritinib for tumors with specific KIT or PDGFRA changes
This Phase 2 trial studies avapritinib, a targeted medicine, for people whose cancer has specific KIT or PDGFRA genetic changes. It may help shrink or slow growth of certain advanced cancers, including some brain tumors, when standard treatments have not worked or for specific glioblastoma cases.
Houston, TexasAges 18 years+ - NCT04732065RecruitingPhase 1
ONC206 for certain brain tumors in children and young adults
This Phase 1 study tests ONC206, a new targeted medicine, for diffuse midline gliomas (DMG) with a specific gene change (H3K27 altered) and for some other recurrent brain/spinal cord cancers. It is designed to find the right dose and see whether it can control or shrink tumors after initial treatment or when the cancer returns.
San Francisco, CaliforniaAges 2–21 - NCT07332481RecruitingPhase 3
Testing enpatoran for lupus affecting the skin
This trial tests if a drug called enpatoran can help people with lupus that causes skin rashes, like discoid lupus or subacute cutaneous lupus. It may be for those with or without systemic lupus.
Los Angeles, CaliforniaAges 18–75 - NCT07840196RecruitingPhase 1
Investigational drug NG004 for recent spinal cord injury
This trial tests a new drug called NG004 given by injection around the spinal cord. It aims to help people with recent incomplete spinal cord injuries recover function. The drug is given within the first month after injury and may be an option for those who meet the health criteria.
BayreuthAges 18–75 - NCT06553625Recruiting
RF ablation study for pain or CNS conditions
This study observes how well a Boston Scientific radiofrequency (RF) system works for treating pain or central nervous system (CNS) conditions. It helps researchers understand real-world benefits for patients scheduled for this procedure.
CologneAges Any age - NCT04472130Recruiting
Neurodegenerative disease registry for adults
This study collects health information from adults with neurodegenerative diseases to help researchers learn more about these conditions and improve future care.
Hong KongAges 18–80 - NCT06792799RecruitingEarly Phase 1
CAR-NK cells for B-cell autoimmune diseases
This early phase trial tests a new treatment made from immune cells (CAR-NK cells) that target and destroy overactive B cells. It may help people with lupus, certain kidney diseases, or nephrotic syndrome that hasn't responded to standard therapies.
Hangzhou, ZhejiangAges 3 years+ - NCT05349006RecruitingPhase 3
Azathioprine for first attack in MOG antibody disease
This Phase 3 trial studies whether azathioprine can help prevent problems after a first attack of MOG antibody–related inflammation of the brain/spinal cord. It’s for adults with a recent first episode and confirmed MOG antibodies.
BordeauxAges 18 years+ - NCT06418048Recruiting
Infectious disease registry and biobank trial
This study collects medical information and optional biological samples (like blood or saliva) from people with an active or suspected infection. The goal is to build a large database that can help researchers better understand infectious diseases and develop new ways to diagnose and treat them.
MilanAges 18 years+ - NCT06941129RecruitingPhase 1
CAR T-cell therapy for resistant autoimmune diseases
This trial tests a new type of immune therapy called CAR T-cells that target two markers on your B cells (CD19 and BCMA). It is for people with certain autoimmune diseases that have not improved or have come back after standard treatments. The goal is to see if this therapy can help control the disease.
TianjinAges 18 years+ - NCT06828042RecruitingPhase 1/Phase 2
CAR-γδT cells for refractory autoimmune diseases
This trial tests a new type of immune cell therapy (CAR-γδT cells) that targets a protein called CD19 on your own B cells. It is for people with certain autoimmune diseases that have not gotten better with standard treatments. The goal is to see if this therapy can safely control the disease.
BeijingAges 18–80 - NCT06794008RecruitingPhase 2
CAR-T cell therapy for hard-to-treat autoimmune diseases
This trial tests a new treatment using your own immune cells (called CAR-T cells) designed to target and attack cells that cause autoimmune diseases. It is for people with lupus, Sjögren's syndrome, inflammatory myopathy, scleroderma, Behcet's disease, ANCA-associated vasculitis, IgG4-related disease, antiphospholipid syndrome, or thrombotic thrombocytopenic purpura who have not improved with standard therapies.
Beijing, Beijing MunicipalityAges 18–65 - NCT06925542RecruitingPhase 1
Study of CTX112 for adults with autoimmune disease
This trial tests an experimental cell therapy called CTX112 for people with lupus, scleroderma, or inflammatory myositis that hasn't responded well to standard treatments. The goal is to see if it's safe and if it can help control the disease.
La Jolla, CaliforniaAges 18–70 - NCT07087873Recruiting
Testing brain stimulation for memory problems in inflammatory diseases
This trial tests if a gentle electrical current applied to the scalp can improve memory and thinking in people with certain inflammatory conditions that affect the brain and spinal cord.
Beijing, Beijing MunicipalityAges 18–60 - NCT07029386Recruiting
Brain stimulation for thinking problems in MS and NMOSD
This trial tests a gentle brain stimulation technique (transcranial electrical stimulation) to see if it can improve thinking and memory problems in people with inflammatory brain diseases like MS or NMOSD. It may help if you feel your thinking has slowed down.
BeijingAges 18–65 - NCT06942611Recruiting
Electrical brain stimulation for chronic pain from nerve inflammation
This study tests a noninvasive brain stimulation technique (transcranial electrical stimulation) to see if it can reduce chronic pain in people with conditions like multiple sclerosis or neuromyelitis optica. It aims to offer a new, drug-free option for pain relief without major side effects.
BeijingAges 18–65 - NCT06649058RecruitingPhase 2
Study on combining drugs and radiation for brain metastases
This trial is for people with cancer that has spread to the brain (brain metastases). It tests a new approach where you start a systemic therapy (drugs that travel through your body) and later add focused radiation to the brain tumors, instead of treating them right away. The goal is to see if this sequence works well and avoids unnecessary side effects.
Houston, TexasAges 18 years+ - NCT07526350RecruitingEarly Phase 1
MTS109 for Hard-to-Treat Autoimmune Diseases
This early-stage trial tests a new treatment called MTS109 for autoimmune diseases (like lupus, muscle inflammation, scleroderma, vasculitis, or Sjögren's syndrome) that haven't responded well to standard medications. The goal is to see if MTS109 can help control disease that keeps flaring or getting worse despite current treatments.
Shanghai, Shanghai MunicipalityAges 18–65
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Common questions
- Are there clinical trials for nervous system diseases?
- Yes. Clin2 currently lists 264 recruiting nervous system diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a nervous system diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a nervous system diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.