Study on combining drugs and radiation for brain metastases
Treatments studied
Part of Brain & nervous system, Cancer clinical trials.
This trial is for people with cancer that has spread to the brain (brain metastases). It tests a new approach where you start a systemic therapy (drugs that travel through your body) and later add focused radiation to the brain tumors, instead of treating them right away. The goal is to see if this sequence works well and avoids unnecessary side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have at least one brain tumor that is 5 mm or larger, which has not been treated with focused radiation before.
- Your cancer must have spread to the brain from another primary cancer (like breast, lung, melanoma, etc.).
- You should be in generally good health, able to be up and about (ECOG score 0 or 1).
- You must not have symptoms from brain tumors that need more than 2 mg of dexamethasone (a steroid) per day.
- You must not have had whole-brain radiation in the past.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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