Clinical trials
Obesity and Cardiovascular Risk clinical trials
Below are recruiting obesity and cardiovascular risk clinical trials, each written for real people, not researchers. We’re tracking 66 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04040777Recruiting
Cardiometabolic risk registry for adults
This study is a health registry that collects information about risk factors for heart and metabolic problems in adults. It may help doctors better understand who is at higher risk and guide future prevention strategies.
Pilar, Buenos AiresAges 18 years+ - NCT07779343Recruiting
Multidisciplinary support for adults living with obesity
This study tests a programme that combines medical, dietary, and behavioural support to help adults with obesity lose weight and improve their health. It looks at how well the programme works in everyday clinic settings.
AlgiersAges 18–65 - NCT06714058Recruiting
Heart risk in people with obesity
This study looks at heart health risks in people with obesity who have not had heart disease before. It aims to understand how obesity affects cardiometabolic risk factors.
Bologna, BOAges 18 years+ - NCT07447362Recruiting
Managing heart health risks in adults
This study checks if a program to manage heart health risks works better than usual care. If you have a risk factor like high blood pressure, diabetes, or smoking, you may qualify.
Santiago, Santiago MetropolitanAges 18 years+ - NCT07404150Enrolling by invitation
Lifestyle program for women with obesity
This trial tests a year-long lifestyle program designed to help women with obesity improve their eating, well-being, and health habits. You will meet with a group for support and guidance.
Calgary, AlbertaAges 35–75 - NCT07297290RecruitingPhase 3
Testing Metformin for Weight Loss in Obesity
This trial tests whether metformin, a common diabetes medicine, can help people with obesity lose weight. It is for people who do not have diabetes and have not used weight loss treatments in the past year.
Enugu, Enugu StateAges 20–59 - NCT06967389Recruiting
Helping kids with severe obesity reduce heart risks
This trial tests whether semaglutide can lower heart disease risks in children with extreme obesity. It aims to improve weight and heart health over time.
Lexington, KentuckyAges 12–17 - NCT07742917Recruiting
Personalized lifestyle program for weight management
This program tests a personalized lifestyle plan designed to help you manage your weight and improve your health. It uses your genetic information and other personal data to tailor the support you receive.
Abu DhabiAges 25–50 - NCT07783802RecruitingPhase 2
Study of clazakizumab for adults with high inflammation and heart risk
This study tests whether clazakizumab can reduce the risk of heart attacks or strokes in people with high levels of inflammation (measured by a blood test called hsCRP) and conditions like heart disease, obesity, diabetes, high blood pressure, or kidney disease. If you qualify, you'll receive either the study drug or a placebo to see if it helps lower your risk.
Huntsville, AlabamaAges 18 years+ - NCT07404189Enrolling by invitation
Obesity management using a digital health platform
This trial tests whether adding a digital health app (Nutu™) to primary care obesity treatment helps people lose weight. It is for patients already enrolled in the FLOW program at UAB.
Birmingham, AlabamaAges 18 years+ - NCT07238556Recruiting
Digital exercise program for cardiovascular risk
This study tests a new digital tool that helps clinicians prescribe personalized exercise plans to patients with cardiovascular risk factors like high blood pressure, diabetes, or obesity. Participation involves using the tool and following an exercise plan for a few months to see if it improves health.
Farmington, ConnecticutAges 18–64 - NCT07551960Enrolling by invitation
Testing a Health Risk Prevention Platform for Adults
This study tests a digital platform called STELA that helps adults reduce their risk of heart disease and stroke by identifying and managing modifiable health factors like diet, exercise, and stress. You'll complete health assessments online to see if this preventive approach works.
Třinec, Moravian-Silesian RegionAges 18–80 - NCT07673822Enrolling by invitation
Heart, kidney, and metabolic disease study in Korea
This study looks at how common heart, kidney, and metabolic problems are in Korea by using health insurance records. It will help doctors understand how often these conditions happen together.
SeoulAges 19 years+ - NCT07463196RecruitingPhase 1
Study of ACI-19764 for healthy people and those with heart risks
This trial tests an experimental drug called ACI-19764 to see how safe it is, how the body handles it, and how it affects the immune system. It's for healthy adults and for adults with heart-related risk factors like obesity or type 2 diabetes.
GroningenAges 18–75 - NCT07255300Recruiting
Fasting-mimicking diet for aging and health in adults
This study tests whether a special low-calorie diet that mimics fasting can help reduce risk factors for aging and age-related diseases. It is for healthy adults aged 30 to 65 who are willing to follow this diet for several days each month.
Varapodio, Calabria, ItalyAges Any age - NCT07343804Recruiting
Dental root canal and heart disease risk study
This trial tests whether treating a tooth infection with a root canal can lower blood markers linked to heart risk in people with stable heart disease.
Rohtak, HaryanaAges 30 years+ - NCT06693934Recruiting
Prevention program for young adults at risk of diabetes
This trial offers a prevention program for young adults aged 18 to 44 who have at least one risk factor for diabetes but do not already have diabetes. The program aims to help prevent or delay the onset of diabetes.
Hong KongAges 18–44 - NCT00001853Recruiting
Heart disease risk study in Black adults
This study looks at how obesity and blood fat (triglyceride) levels affect heart disease risk differently in Black men and women. You may join if you're a healthy Black adult between 18 and 70, without diabetes.
Bethesda, MarylandAges 18–70 - NCT07581431RecruitingPhase 1
Testing ISM8969 in healthy and obese adults with heart disease risk
This early-stage trial tests a new drug called ISM8969 to see if it's safe and how the body handles it. Participants are either healthy adults or adults who are overweight with risk factors for heart disease, like high blood pressure or high cholesterol.
Melbourne, VictoriaAges 18–80 - NCT04036357Recruiting
Study of liver fat disease with heart and metabolism problems
This study looks at people with fatty liver disease and common health issues like obesity, diabetes, high blood pressure, or abnormal cholesterol. It may help researchers understand how liver fat and heart/metabolism problems relate and how they affect health over time.
RomeAges 18–80 - NCT06619444Recruiting
Resistance exercise and heart health in overweight adults
This study looks at how different amounts of resistance training (like lifting weights) affect heart health in people who are overweight and don't exercise much. It may help find the best exercise dose to improve cardiovascular health.
Pittsburgh, PennsylvaniaAges 40 years+ - NCT06949722Recruiting
Can better sleep help your heart?
This study tests if improving poor sleep can reduce your risk of heart disease. You will wear a ring to track your sleep and get support to build healthier sleep habits.
SingaporeAges 40–70 - NCT07478653Recruiting
Dental health study for teens with severe obesity
This study looks at whether gum health is linked to heart health in teens with severe obesity. It may help find ways to reduce heart risks by improving dental care.
Lexington, KentuckyAges 12–17 - NCT06446531RecruitingPhase 1
Preventing diabetes progression in Hispanic adults
This trial tests if a medication can prevent or slow the progression from prediabetes to type 2 diabetes and reduce heart risk. It is for Hispanic adults who are overweight and have prediabetes.
San Antonio, TexasAges 18 years+
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Common questions
- Are there clinical trials for obesity and cardiovascular risk?
- Yes. Clin2 currently lists 66 recruiting obesity and cardiovascular risk studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity and cardiovascular risk trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity and cardiovascular risk trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.