Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,500 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06293703Recruiting
Leg length ratio and weight loss after gastric bypass
This study looks at how the length of different parts of your small intestine affects weight loss after Roux-en-Y gastric bypass surgery. It may help doctors tailor the surgery for better results.
Cleveland, OhioAges 18–70 - NCT06302803Recruiting
Modified intermittent eating for weight loss trial
This trial tests a modified intermittent eating plan to help people with obesity lose weight and keep it off. It compares different eating schedules to see which works best for long-term weight control.
Guangzhou, GuangdongAges 18–75 - NCT06305208Recruiting
UK registry for weight loss endoscopy procedures
This study collects information from patients in the UK who have a weight loss procedure done through an endoscope (a thin tube down the throat). It helps doctors learn more about how well these procedures work and how safe they are.
LondonAges 18–99 - NCT06308757Recruiting
Studying a very low calorie keto diet for fatty liver disease with scarring
This trial tests whether a very low calorie ketogenic diet (a strict low-carb, high-fat diet) can help people with non-alcoholic steatohepatitis (NASH) who have liver scarring. Participants will follow this diet for a year and have two liver biopsies to see if their liver health improves.
BolognaAges 18 years+ - NCT06309563Recruiting
Essential amino acid diet for severe obesity
This study tests whether replacing some foods with essential amino acids (protein building blocks) can improve metabolism in people with severe obesity. It aims to find a non-surgical way to boost weight loss.
Oggebbio, VerbaniaAges 45–65 - NCT06309576Recruiting
Study on body weight regulation using liquid meals
This study tests how the body regulates weight by having participants drink only a special liquid meal for two days. It may help researchers understand weight changes in people with low or high body weight.
Baton Rouge, LouisianaAges 18–40 - NCT06323070Recruiting
Watermelon vs. low-fat cookies for wellness
This trial compares eating watermelon or low-fat cookies to see how they affect your overall wellness. It will help determine if one snack is better for your health.
San Diego, CaliforniaAges 18–50 - NCT06323538Recruiting
Plant-based diets and health (COPLANT)
This study looks at how different plant-based diets affect your health. Researchers will collect information through questionnaires and blood samples to understand the benefits of eating more plants.
ViennaAges 18–69 - NCT07332741RecruitingPhase 2
Food as medicine for better blood pressure
This study tests a program that provides healthy food and support to help people with high blood pressure and a BMI of 30 or higher eat better and control their blood pressure. If you join, you'll get guidance on the DASH diet (a heart-healthy eating plan) and text messages to help you stay on track.
Chicago, IllinoisAges Any age - NCT06858761Recruiting
Robot-assisted weight loss surgery: cost and results study
This study looks at whether using a robot during weight loss surgery is worth the cost. It compares outcomes for people having their first bariatric surgery or a repeat surgery for complications.
BordeauxAges 18–70 - NCT06329349Recruiting
Metabolic flexibility and lifestyle change study
This study looks at how your body's metabolism responds to lifestyle changes like diet or exercise. If you are an adult with obesity (BMI over 30) and no major health issues, you may be able to join a program that helps you understand your body's energy use.
PragueAges 25–45 - NCT06329544Recruiting
Study of a high-fructose diet and gut health
This trial tests how a high-fructose diet affects your gut bacteria and overall metabolic health. It is for people who already know they don't absorb fructose well (fructose malabsorbers) and want to understand how this sugar impacts their body.
New York, New YorkAges 25–45 - NCT06338631Recruiting
Early kidney check in people with excess weight
This study looks for early signs of kidney problems in people with excess weight, even if they are otherwise healthy. It aims to understand how weight affects kidneys before any disease develops.
MilanAges 18–60 - NCT06341179Recruiting
Does more sleep help children learn and manage weight?
This study tests whether helping children sleep longer each night can help them learn better and manage their weight. It is for children ages 6–12 who are above a healthy weight and sleep 9 hours or less per night.
CopenhagenAges 6–12 - NCT06354088RecruitingPhase 1
Study of alpelisib for insulin resistance
This study tests a single dose of a drug called alpelisib (a PI3K inhibitor) to see how it affects insulin and blood sugar in people who are either insulin sensitive or insulin resistant. The goal is to understand why some people become resistant to insulin, which may help find new treatments for diabetes and related conditions.
New York, New YorkAges 18–70 - NCT06364644Recruiting
Reducing heart failure risk in low-income adults with diabetes
This study looks at how low income and diabetes together raise the risk of heart failure. It offers a program to help you manage your health and reduce that risk.
Baltimore, MarylandAges 30–70 - NCT06366399Recruiting
Timing of resistance exercise for weight management
This study tests if doing resistance exercises (like lifting weights) in the morning or afternoon is better for weight management. You may qualify if you are between 50 and 74 years old, are overweight but generally healthy, and have not been very active with strength training.
Salt Lake City, UtahAges 50–74 - NCT06370845RecruitingEarly Phase 1
Smell test to find natural odor in spinal fluid
This study investigates whether a natural smell can be detected in the fluid around your brain and spine (cerebrospinal fluid) after you sniff it. It aims to understand how smells enter the brain in people with different body weights who are already scheduled for a routine spinal tap.
BaselAges 18–60 - NCT06372015Recruiting
Diet program vs bariatric surgery for liver health
This study compares two ways to help people with obesity and liver problems: a special diet program or weight-loss surgery. Researchers will look at changes in fats, immune system, and genetic markers to see which approach works better.
Castellana Grotte, BariAges 18 years+ - NCT06374368Recruiting
Small bowel diversion surgery for obesity
This trial tests a surgery called small bowel diversion to help people with obesity lose weight. It may also improve blood sugar control for those with type 2 diabetes.
OstravaAges 18–65 - NCT06382298Recruiting
Cottonseed oil vs. similar oil for heart health
This study compares the effects of cottonseed oil versus a similar oil on heart health. It is for people with high cholesterol or who are overweight and want to see if changing cooking oils can improve their cholesterol levels.
Athens, GeorgiaAges 25–75 - NCT06384313Recruiting
Butyrate supplement for preventing diabetes
This study tests if a special type of fat (butyrate) can help prevent diabetes in people who are overweight and have early signs of blood sugar problems. You would take a supplement for several weeks to see if it improves how your body handles sugar.
Maastricht, LimburgAges 20–70 - NCT06390189Recruiting
Inflammation resolution in heart and metabolic health
This study examines how your body naturally resolves inflammation, which is important for heart health and conditions like diabetes. It involves blood draws and tests to understand how inflammation works.
AarhusAges 18–75 - NCT06390345Recruiting
Telehealth lifestyle and exercise for COPD and sleep apnea
This study tests a telehealth program that combines lifestyle coaching and exercise to help people with both COPD and sleep apnea improve their breathing and daily function. It may be a good fit if you are overweight, have a history of smoking, and feel short of breath during light activity.
Boise, IdahoAges 18 years+
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,500 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.