Clinical trials
Overweight or Obesity clinical trials
Below are recruiting overweight or obesity clinical trials, each written for real people, not researchers. We’re tracking 1,536 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07575932RecruitingPhase 2
Testing New Weight Loss Medications PF-08653945 and PF-08653944
This study tests two new experimental medications designed to help adults lose weight and improve weight-related health conditions like high blood pressure and sleep apnea. Participants will take one of these medications to see if it's safe and effective.
Chandler, ArizonaAges 18 years+ - NCT05770570RecruitingPhase 2
Diet and activity texting support for Mexican American drivers
This Phase 2 study tests a structured program using texts and recordings to help people improve diet and physical activity for weight loss. It focuses on specific Spanish-speaking groups and also includes a separate track for taxi/FHV drivers.
New York, New YorkAges 21 years+ - NCT05038683Recruiting
Child weight program study: new treatment vs usual care
This trial tests a structured obesity treatment program for children compared with the usual (conventional) approach. It may help your child get support to improve healthy weight habits.
Ballerup Municipality, BallerupAges 6–11 - NCT07595549RecruitingPhase 3
Testing Berobenatide for Weight Loss in Overweight Adults
This study tests a new medicine called berobenatide to help people with overweight or obesity lose weight. The medicine may also help improve related health conditions like high blood pressure, high cholesterol, or type 2 diabetes.
Canoga Park, CaliforniaAges 18 years+ - NCT07578584RecruitingPhase 1
Safety study of NNC0497-0040 in healthy and overweight adults
This early-stage study tests a new investigational medication in three groups: healthy adults with normal weight, adults who are overweight or obese, and men with type 1 diabetes who are also overweight. The research aims to understand how safe the medication is and how the body processes it.
NeussAges 18–55 - NCT05277558Recruiting
MRI and brain testing in teens at risk for type 2 diabetes
This study looks at brain health in teens with normal weight, overweight, or obesity who are at risk for type 2 diabetes. It may help researchers understand how weight and diabetes risk affect the brain, using MRI scans and learning/memory tests.
St Louis, MissouriAges 12–17 - NCT07009171RecruitingPhase 2
Testing KDS2010 for weight loss in overweight or obese adults
This study tests a new medication called KDS2010 for people who are overweight or have obesity. The goal is to see if it helps with weight loss when combined with diet and exercise.
Suwon, Gyeonggi-doAges 18 years+ - NCT07075146RecruitingPhase 3
Comparing two HIV treatments for people with overweight or obesity
This trial compares two different daily pill combinations for people newly starting HIV treatment who are overweight or have obesity. It aims to see which one works better for controlling the virus and managing weight.
Mexico CityAges 18–70 - NCT07227051Recruiting
Phone app and fitness tracker for weight loss study
This study tests a smartphone app and fitness tracker to help people lose weight by monitoring their diet and activity. Participants get feedback and support through the app.
Milwaukee, WisconsinAges 18 years+ - NCT07229027Recruiting
Global overweight and obesity registry study
This study aims to develop better ways to measure how overweight or obesity affects your life, including severity, quality of life, and costs. You will fill out surveys to help researchers understand your experience.
Milton KeynesAges 18 years+ - NCT07255274Recruiting
Sleep help for teens with overweight or obesity
This study tests whether a behavior-based sleep program can help teenagers aged 13–17 who are overweight or have obesity and also have sleep problems. The goal is to see if improving sleep can help with weight management.
CovilhaAges 13–17 - NCT07340125Recruiting
Pistachio snacking and metabolic flexibility study
This study tests whether eating pistachios as a snack can improve how your body uses energy and manages metabolism. It looks at people who are overweight, sleep poorly, and don't exercise much.
Columbia, South CarolinaAges 25–45 - NCT07342855Recruiting
Healthy lifestyle program for children with obesity
This trial looks at how a community healthy lifestyle program helps children with obesity. Your family would join a program that supports healthy eating and physical activity, and researchers will track your child's progress.
Dallas, TexasAges 6–14 - NCT07243171RecruitingPhase 1/Phase 2
Oral Ecnoglutide for overweight or obesity
This trial tests an oral medication called Ecnoglutide to help people with overweight or obesity lose weight. It is for Chinese adults who are not diabetic and have a stable weight.
Beijing, Beijing MunicipalityAges 18–65 - NCT07575399RecruitingPhase 3
Switching to a New Weight-Loss Medication From Current GLP-1
This trial tests whether switching from your current GLP-1 medication (like Ozempic or Wegovy) to a new drug called maridebart cafraglutide works as well or better for weight management. You must have already lost at least 10% of your body weight on your current GLP-1 and be doing well with it.
Pelham, AlabamaAges 18–99 - NCT07775404RecruitingPhase 3
Weight loss medication for Asian adults with obesity or overweight
This study tests an investigational medication called elecoglipron for weight loss in Asian adults who are overweight or have obesity, with or without type 2 diabetes. It may help participants lose weight and improve health.
BaotouAges 18 years+ - NCT07784725RecruitingPhase 3
Study of a weight loss injection for adults with obesity
This study tests a new medicine to help adults with obesity or overweight lose weight. It's for people who have had trouble losing weight in the past and don't have diabetes.
Dothan, AlabamaAges 18 years+ - NCT06672549RecruitingPhase 3
Weight loss medication study for children with obesity
This trial tests a medication for children and teens with obesity or overweight who have not been able to lose enough weight with diet and exercise alone. It aims to see if a new treatment can help them safely lose weight and improve related health problems.
Tucson, ArizonaAges 6–17 - NCT06672939RecruitingPhase 3
Orforglipron for Weight Loss in Teens
This study tests a once-daily pill (orforglipron) to help adolescents with obesity or overweight plus related health problems lose weight. It offers a new option for teens who have struggled to lose weight with diet and exercise alone.
Oxnard, CaliforniaAges 12–17 - NCT06937086RecruitingPhase 3
Mirikizumab plus tirzepatide for UC with obesity
This study tests whether adding mirikizumab to the weight-loss drug tirzepatide helps people with moderate-to-severe ulcerative colitis who also have obesity or overweight. It aims to see if the combination reduces bowel inflammation and helps with weight management.
Dothan, AlabamaAges 18–70 - NCT06937099RecruitingPhase 3
Testing two drugs for Crohn's with weight issues
This trial tests two study drugs, mirikizumab and tirzepatide, in people with moderate to severe Crohn's disease who also have overweight or obesity. The goal is to see if these treatments can help control Crohn's symptoms and inflammation.
Dothan, AlabamaAges 18–70 - NCT07662122RecruitingPhase 2
Testing a new weight loss medication in adults with obesity or overweight
This trial tests an investigational drug called BI 3034701 to see if it helps people lose weight. It is for adults who are obese or overweight with at least one weight-related health problem.
Birmingham, AlabamaAges 18–74 - NCT07738614RecruitingPhase 1
Testing an investigational weight loss medicine for adults with overweight or obesity
This study tests an experimental medicine (eloralintide) to see if it can help people with overweight or obesity lose weight without having diabetes. The medicine works by affecting hormones that help control appetite and body weight.
San Antonio, TexasAges 18–65 - NCT07685808RecruitingPhase 2
Testing a weight loss injection for people with overweight or obesity
This study tests an injectable medication called Olatorepatide to help people with overweight or obesity lose weight. It is only for people without diabetes who meet specific body mass index (BMI) requirements.
Walnut Creek, CaliforniaAges 18 years+
Hear when a new Overweight or Obesity trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Overweight or Obesity trials by city
Studies with a site in or near these metro areas.
Overweight or Obesity trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for overweight or obesity?
- Yes. Clin2 currently lists 1,536 recruiting overweight or obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a overweight or obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a overweight or obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.