Clinical trials
Obesity clinical trials
Excess body weight that increases the risk of many other health conditions. We’re tracking 1,433 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06782529RecruitingPhase 4
Knee injection study for patients with obesity and arthritis
This study tests if steroid injections for knee arthritis work in people with obesity. It may help you manage pain and avoid surgery.
Jacksonville, FloridaAges 55–85 - NCT06785064Recruiting
Helping with long-term weight loss maintenance support
This study tests an extended care program designed to help people keep weight off after losing it. You would join with a buddy (friend or family member) and attend online sessions via Zoom, along with a few in-person check-ins at the university.
Birmingham, AlabamaAges 18 years+ - NCT05838950Recruiting
Short high-intensity exercise program for cardiometabolic health
This trial studies whether a structured, short high-intensity exercise program can improve health markers related to weight, blood sugar, and blood fats in young adults with obesity. It may help you see if this kind of exercise leads to measurable health improvements.
Syracuse, New YorkAges 18–25 - NCT06781229Recruiting
Gum bacteria in people preparing for weight loss surgery
This trial looks at the bacteria in the mouths of people with a BMI of 30 or higher who are scheduled for weight-loss surgery. The goal is to understand how gum health and body weight are connected.
ToulouseAges 18 years+ - NCT06776081Recruiting
Weight loss, fat cell particles, and blood vessel health
This trial looks at how weight loss changes tiny particles released from fat cells and whether that improves blood vessel function. It may help understand how losing weight can protect your heart.
Boulder, ColoradoAges 40 years+ - NCT06049420Recruiting
Lifestyle medicine for rural patients with chronic disease
This trial tests whether exercise therapy can help people with two or more chronic conditions like obesity, diabetes, or heart disease. It's designed for rural patients and requires a referral from your doctor.
Lewisburg, West VirginiaAges 18–64 - NCT06753669Recruiting
Mothers' action project for child health
This study looks at how to help mothers from South Asian communities support their child's health and development. You and your child would join a program that provides guidance and resources over 12 months.
New York, New YorkAges 1–45 - NCT06759701RecruitingEarly Phase 1
Weight loss drug before prostate cancer surgery pilot study
This study tests if taking tirzepatide (a weight loss medicine) before prostate removal surgery is safe and helpful for overweight men with intermediate-risk prostate cancer. It aims to see if losing weight can improve surgery outcomes.
Houston, TexasAges 18 years+ - NCT06750120Recruiting
Improving nutrition during pregnancy in Guatemala
This study tests ways to improve nutrition in pregnant women in Guatemala. It aims to help both mother and baby stay healthy.
Tecpán Guatemala, Departamento de ChimaltenangoAges 16 years+ - NCT06730113Recruiting
Young adults with type 2 diabetes and heart health study
This study looks at how type 2 diabetes starting in youth affects the heart over time. It also includes teens and young adults who are overweight or lean, and their biological parents, to compare heart health across these groups.
Washington D.C., District of ColumbiaAges 12–25 - NCT06169033Recruiting
Can belly fat scans predict weight-loss surgery success?
This study looks at how fat around your belly and inside your abdomen, seen on a CT scan, can predict how well bariatric (weight-loss) surgery will work for people with type 2 diabetes.
BeijingAges 16–70 - NCT06338631Recruiting
Early kidney check in people with excess weight
This study looks for early signs of kidney problems in people with excess weight, even if they are otherwise healthy. It aims to understand how weight affects kidneys before any disease develops.
MilanAges 18–60 - NCT05443100Recruiting
Testing whole-body cold therapy for metabolic, neurologic, or fibromyalgia pain
This trial studies whether a whole-body cold therapy called “WBC” can help people with certain metabolic conditions, neurologic conditions, or fibromyalgia. You may be able to join if you meet age and weight requirements and don’t have certain medical or safety risks.
Oggebbio, Verbano-Cusio-OssolaAges 18–65 - NCT06719102Recruiting
Support for mothers and caregivers with new babies
This study looks at how mothers and other caregivers can help their babies grow and thrive. You and your baby would be videotaped during some play and feeding sessions to understand your interactions better.
Austin, TexasAges birth–90 years - NCT06724172Recruiting
Comparing health programs for pregnant mothers from diverse backgrounds
This study tests two different health programs for pregnant women to see which one helps mothers and babies more. You may join if you are early in your pregnancy, identify as Black, Hispanic, or have Medicaid, and speak English or Spanish.
Palo Alto, CaliforniaAges 18 years+ - NCT06724406Recruiting
Family weight loss program for Black adults
This study tests a family-centered weight loss program for Black adults and their family members. You and a family member or partner will work together to lose weight and improve health.
Chapel Hill, North CarolinaAges 18–75 - NCT06707012RecruitingPhase 4
Metformin plus antidepressants for depression in obesity
This trial tests whether adding metformin (a diabetes medicine) to usual antidepressant treatment can help improve depression in people who are overweight or obese. It is for adults age 18–44 who are newly diagnosed with depression and do not have diabetes.
Karachi, SindhAges 18–45 - NCT06715787Recruiting
Perinatal support program for pregnant people
This trial tests a support program for pregnant individuals who qualify for certain food assistance benefits. It aims to see if the program helps with pregnancy and infant health.
Los Angeles, CaliforniaAges 18 years+ - NCT06714929Recruiting
School water study for students in grades K-5
This study looks at how a new water program in schools might affect student health and hydration. It includes watching what kids drink at lunch, checking teeth and body weight for older students, and asking 4th and 5th graders and staff about their drinks.
Henrico, VirginiaAges 4 years+ - NCT06705400Recruiting
The Bloom Study: A Healthy Start for Mom and Baby
This study follows first-time mothers and their babies from pregnancy to early childhood, using digital tools to support a healthy start. It aims to learn how to improve health and well-being for both mom and baby.
CopenhagenAges birth–6 months - NCT06686537RecruitingPhase 2
Study on metabolism and hormones in women
This study looks at how metabolism and hormones are connected in women. It tests a treatment to see if it can improve metabolic health related to the menstrual cycle.
Aurora, ColoradoAges 18–38 - NCT06686875Enrolling by invitation
Chronic belly pain after sleeve gastrectomy study
This study looks at long-term belly pain in people who had a sleeve gastrectomy 3 months to 5 years ago. It aims to understand the pain better to help future patients.
WarsawAges 18 years+ - NCT06691100Recruiting
How one workout changes gut bugs in women
This study looks at how a single workout changes the bacteria in your gut. It compares women who are very fit with women who don't exercise much, and includes women with different body types.
Washington D.C., District of ColumbiaAges 21–40 - NCT03699228Recruiting
Low-dose chest CT study for adults in China
This study is looking at people ages 30 to 90 who are willing to get a low-dose chest CT scan. It may help researchers improve how health data is collected and understood from scans.
Wuhu, AnhuiAges 30–90
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Common questions
- Are there clinical trials for obesity?
- Yes. Clin2 currently lists 1,433 recruiting obesity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a obesity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a obesity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.